|
|
老年髋部骨折围术期血栓形成的危险因素
|
Abstract:
髋部骨折是老年人群中最常见的骨折类型，多因老年人骨质疏松、易跌倒等原因造成。一旦发生髋部骨折，即使立即手术治疗，也需卧床制动恢复，年龄、创伤，身体机能等多方面原因导致该类患者在围术期易形成下肢深静脉血栓，本文就既往文献对老年髋部骨折围术期下肢深静脉血栓的形成做出探讨，旨在为临床预防围术期血栓形成提供参考。
Hip fractures are the most common type of fracture in the elderly population, often caused by factors such as osteoporosis and susceptibility to fall in the elderly. Once a hip fracture occurs, even immediate surgical treatment requires bed rest and immobilization for recovery. Due to various factors such as age, trauma, and physical function, these patients are prone to developing lower limb deep vein thrombosis during the perioperative period. This article explores the formation of lower limb deep vein thrombosis during the perioperative period of elderly hip fractures based on previous literature, aiming to provide reference for clinical prevention of perioperative thrombosis.
| [1] | 车宇虹, 等. 老年髋部骨折围手术期风险因素及风险管理方式分析[J]. 解放军预防医学杂志, 2019, 37(7): 182-183. |
| [2] | Haleem, S., et al. (2008) Mortality Following Hip Fracture: Trends and Geographical Variations over the Last 40 Years. Injury, 39, 1157-1163. https://doi.org/10.1016/j.injury.2008.03.022 |
| [3] | The Hip Fracture Accelerated Surgical Treatment and Care Track (HIP ATTACK) Investigators (2014) Accelerated Care versus Standard Care among Patients with Hip Fracture: The HIP ATTACK Pilot Trial. CMAJ, 186, E52-E60. https://doi.org/10.1503/cmaj.130901 |
| [4] | Bhandari, M. and Swiontkowski, M. (2017) Management of Acute Hip Fracture. The New England Journal of Medicine, 377, 2053-2062. https://doi.org/10.1056/NEJMcp1611090 |
| [5] | Berry, S.D., et al. (2018) Association of Clinical Outcomes with Surgical Repair of Hip Fracture vs Nonsurgical Management in Nursing Home Residents with Advanced Dementia. JAMA Internal Medicine, 178, 774-780. https://doi.org/10.1001/jamainternmed.2018.0743 |
| [6] | Neuman, M.D., et al. (2014) Survival and Functional Outcomes after Hip Fracture among Nursing Home Residents. JAMA Internal Medicine, 174, 1273-1280. https://doi.org/10.1001/jamainternmed.2014.2362 |
| [7] | Raskob, G.E., et al. (2014) Thrombosis: A Major Contributor to Global Disease Burden. Arteriosclerosis, Thrombosis, and Vascular Biology, 34, 2363-2371. https://doi.org/10.1161/ATVBAHA.114.304488 |
| [8] | Arshad, N., et al. (2017) Time Trends in Incidence Rates of Venous Thromboembolism in a Large Cohort Recruited from the General Population. European Journal of Epidemiology, 32, 299-305. https://doi.org/10.1007/s10654-017-0238-y |
| [9] | Radcliff, T.A., et al. (2008) Patient Risk Factors, Operative Care, and Outcomes among Older Community-Dwelling Male Veterans with Hip Fracture. The Journal of Bone & Joint Surgery, 90, 34-42. https://doi.org/10.2106/JBJS.G.00065 |
| [10] | Navarrete, S., et al. (2023) Pathophysiology of Deep Vein Thrombosis. Clinical and Experimental Medicine, 23, 645-654. https://doi.org/10.1007/s10238-022-00829-w |
| [11] | 冯永海, 李宏云, 秦超. 黄芪注射液联合丹参注射液治疗慢性阻塞性肺疾病临床研究及对患者氧化应激水平的影响[J]. 陕西中医, 2018, 39(8): 1048-1050. |
| [12] | 吴林沁, 程波. 骨创伤患者围术期静脉血栓栓塞的危险因素研究进展[J]. 系统医学, 2020, 5(19): 194-198. |
| [13] | Shuster, R., et al. (2018) Variables Associated with Pulmonary Thromboembolism in Injured Patients: A Systematic Review. Injury, 49, 1-7. https://doi.org/10.1016/j.injury.2017.08.024 |
| [14] | Xu, H., et al. (2019) A Nested Case-Control Study on the Risk Factors of Deep Vein Thrombosis for Chinese after Total Joint Arthroplasty. Journal of Orthopaedic Surgery and Research, 14, Article 188. https://doi.org/10.1186/s13018-019-1231-9 |
| [15] | He, S.-Y., et al. (2022) Incidence and Risk Factors of Preoperative Deep Venous Thrombosis Following Hip Fracture: A Retrospective Analysis of 293 Consecutive Patients. European Journal of Trauma and Emergency Surgery, 48, 3141-3147. https://doi.org/10.1007/s00068-021-01861-3 |
| [16] | Do Carmo, L.S., et al. (2013) A High-Fat Diet Increases Interleukin-3 and Granulocyte Colony-Stimulating Factor Production by Bone Marrow Cells and Triggers Bone Marrow Hyperplasia and Neutrophilia in Wistar Rats. Experimental Biology and Medicine, 238, 375-384. https://doi.org/10.1177/1535370213477976 |
| [17] | Purdy, J.C. and Shatzel, J.J. (2021) The Hematologic Consequences of Obesity. European Journal of Haematology, 106, 306-319. https://doi.org/10.1111/ejh.13560 |
| [18] | Ageno, W., et al. (2008) Cardiovascular Risk Factors and Venous Thromboembolism: A Meta-Analysis. Circulation, 117, 93-102. https://doi.org/10.1161/CIRCULATIONAHA.107.709204 |
| [19] | Wilkerson, W.R. and Sane, D.C. (2002) Aging and Thrombosis. Seminars in Thrombosis and Hemostasis, 28, 555-568. https://doi.org/10.1055/s-2002-36700 |
| [20] | Macdonald, P.S., et al. (2003) Short-Term Natural History of Isolated Gastrocnemius and Soleal Vein Thrombosis. Journal of Vascular Surgery, 37, 523-527. https://doi.org/10.1067/mva.2003.149 |
| [21] | Gillet, J.L., Perrin, M.R. and Allaert, F.A. (2007) Short-Term and Mid-Term Outcome of Isolated Symptomatic Muscular Calf Vein Thrombosis. Journal of Vascular Surgery, 46, 513-519. https://doi.org/10.1016/j.jvs.2007.04.040 |
| [22] | Kearon, C. (2003) Natural History of Venous Thromboembolism. Circulation, 107, I22-I30. https://doi.org/10.1161/01.CIR.0000078464.82671.78 |
| [23] | Kline, J.A., et al. (2014) Systematic Review and Meta-Analysis of Pregnant Patients Investigated for Suspected Pulmonary Embolism in the Emergency Department. Academic Emergency Medicine, 21, 949-959. https://doi.org/10.1111/acem.12471 |
| [24] | Patel, P., et al. (2020) Systematic Review and Meta-Analysis of Outcomes in Patients with Suspected Deep Vein Thrombosis. Blood Advances, 4, 2779-2788. https://doi.org/10.1182/bloodadvances.2020001558 |
| [25] | Chopard, R., Albertsen, I.E. and Piazza, G. (2020) Diagnosis and Treatment of Lower Extremity Venous Thromboembolism: A Review. JAMA, 324, 1765-1776. https://doi.org/10.1001/jama.2020.17272 |
| [26] | 于天为, 李玮馨, 苏日古噶. 血栓弹力图与常规凝血四项评价临床患者凝血功能的对比[J]. 实用妇科内分泌电子杂志, 2020, 7(30): 179 193. |
| [27] | 熊泳梅, 赖冬, 林斯恩. 血栓弹力图与常规凝血四项评价临床患者凝血功能的对比[J]. 临床合理用药杂志, 2019, 12(34): 168-169. |
| [28] | Mukai, M. and Oka, T. (2018) Mechanism and Management of Cancer-Associated Thrombosis. Journal of Cardiology, 72, 89-93. https://doi.org/10.1016/j.jjcc.2018.02.011 |
| [29] | Gade, I.L., et al. (2017) The Impact of Initial Cancer Stage on the Incidence of Venous Thromboembolism: The Scandinavian Thrombosis and Cancer (STAC) Cohort. Journal of Thrombosis and Haemostasis, 15, 1567-1575. https://doi.org/10.1111/jth.13752 |
| [30] | Stein, P.D., et al. (2006) Incidence of Venous Thromboembolism in Patients Hospitalized with Cancer. The American Journal of Medicine, 119, 60-68. https://doi.org/10.1016/j.amjmed.2005.06.058 |
| [31] | Tan, L., et al. (2016) Incidence and Risk Factors for Venous Thromboembolism Following Surgical Treatment of Fractures below the Hip: A Meta-Analysis. International Wound Journal, 13, 1359-1371. https://doi.org/10.1111/iwj.12533 |
| [32] | Pedersen, A.B., et al. (2010) Risk Factors for Venous Thromboembolism in Patients Undergoing Total Hip Replacement and Receiving Routine Thromboprophylaxis. The Journal of Bone & Joint Surgery, 92, 2156-2164. https://doi.org/10.2106/JBJS.I.00882 |
| [33] | Moja, L., et al. (2012) Timing Matters in Hip Fracture Surgery: Patients Operated within 48 Hours Have Better Outcomes. A Meta-Analysis and Meta-Regression of over 190,000 Patients. PLOS ONE, 7, e46175. https://doi.org/10.1371/journal.pone.0046175 |
| [34] | Mamtora, P.H., et al. (2020) Peri-Operative Management of Frailty in the Orthopedic Patient. Journal of Orthopaedics, 22, 304-307. https://doi.org/10.1016/j.jor.2020.05.024 |
| [35] | Inoue, T., et al. (2020) Undernutrition, Sarcopenia, and Frailty in Fragility Hip Fracture: Advanced Strategies for Improving Clinical Outcomes. Nutrients, 12, Article 3743. https://doi.org/10.3390/nu12123743 |
| [36] | Ebrahimian, S., et al. (2022) Association of Frailty with Outcomes of Resection for Colonic Volvulus: A National Analysis. PLOS ONE, 17, e0276917. https://doi.org/10.1371/journal.pone.0276917 |
| [37] | Phan, K., et al. (2017) Frailty Is Associated with Morbidity in Adults Undergoing Elective Anterior Lumbar Interbody Fusion (ALIF) Surgery. The Spine Journal, 17, 538-544. https://doi.org/10.1016/j.spinee.2016.10.023 |
| [38] | Yoon, J.Y., et al. (2020) Venous Thromboembolism after Delayed Surgery for a Hip Fracture: A Retrospective Cohort Study. Geriatrics & Gerontology International, 20, 1151-1156. https://doi.org/10.1111/ggi.14055 |
