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Viral Hepatitis B and C: Epidemiological, Clinical and Paraclinical Aspects in the Internal Medicine Department of KARA University Hospital in Togo

DOI: 10.4236/ojim.2024.141012, PP. 131-139

Keywords: Hepatitis B, Hepatitis C, Internal Medicine, Kara University Hospital

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Abstract:

Introduction: Viral hepatitis B and C constitute real public health problems worldwide. The objective of this work was to describe the epidemiological, clinical and paraclinical aspects of viral hepatitis B and c in the internal medicine department of Kara University Hospital. Method: this was a retrospective descriptive study carried out in the Internal Medicine department of Kara University Hospital, over a period of 3 years from March 2020 to April 2023. It included all patients seen in consultation or hospitalized for hepatitis viral B and/or C. Results: A total of 57 patients were included in our study. The average age was 44.30 years ± 16.75 and the M/F sex ratio was 1.38. Married people were in the majority 63.2%. The circumstances of the discovery of viral hepatitis B and C were dominated by abdominal pain in 35.1% of cases and hepatomegaly in 29.8% of cases and in 33.3% of cases, it was during screening voluntary. Patients with viral hepatitis B only accounted for 64.9% of cases; those with only viral hepatitis C represented 31.6% of cases and 3.5% of cases had HVB/HCV co-infection. We recorded 36.8% complications including 52.4% liver cirrhosis and 47.6% hepatocellular carcinomas. During the evolution, there were 03 deaths. Conclusion: the prevalence of hepatitis B and C virus carriage in patients followed in internal medicine at Kara University Hospital is high. It is therefore essential to put in place treatment and prevention strategies against these viruses.

References

[1]  World Health Organization (2017) Hepatitis B—Aide-Mémoire No. 204, World Health Organization, Geneva.
https://www.who.int/fr/campaigns/world-hepatitis-day/2021/fact-sheets
[2]  Daw, M.A. and El-Bouzedi, A. (2014) Prevalence of Hepatitis B and Hepatitis C Infection in Libya: Results from a National Population Based Survey. BMC Infectious Diseases, 14, Article No. 17.
https://doi.org/10.1186/1471-2334-14-17
[3]  Te, H.S. and Jensen, D.M. (2010) Epidemiology of Hepatitis B and C Viruses: A Global Overview. Clinics in Liver Disease, 14, 1-21.
https://doi.org/10.1016/j.cld.2009.11.009
[4]  Iino, S. (2002) Natural History of Hepatitis B and C Virus Infections. Oncology, 62, 18-23.
https://doi.org/10.1159/000048271
[5]  Parry, J. (2010) At Last a Global Response to Viral Hepatitis. Bulletin of the World Health Organization, 88, 801-802.
https://doi.org/10.2471/BLT.10.011110
[6]  El-Serag, H.B. (2007) Epidemiology of Hepatocellular Carcinoma in USA. Hepatology Research, 37, S88-S94.
https://doi.org/10.1111/j.1872-034X.2007.00168.x
[7]  El-Serag, H. and Rudolph, K. (2007) Hepatocellular Carcinoma: Epidemiology and Molecular Carcinogenesis. Gastroenterology, 132, 2557-2576.
https://doi.org/10.1053/j.gastro.2007.04.061
[8]  Lavanchy, D. (2004) Hepatitis B Virus Epidemiology, Disease Burden, Treatment, and Current and Emerging Prevention and Control Measures. Journal of Viral Hepatitis, 11, 97-107.
https://doi.org/10.1046/j.1365-2893.2003.00487.x
[9]  Kodjoh, N. (2015) Fighting Viral Hepatitis B and C in Africa Focus on Benin. Médecine et Santé Tropicales, 25, 141-144.
https://doi.org/10.1684/mst.2015.0439
[10]  Kolou, M., Nadjir, L.K., Anyovi, F., et al. (2018) Seroprevalence of Viral Hepatitis B and C in the General Population of Lome. Journal de la Recherche Scientifique de l’Université de Lomé, 20, 225-233.
[11]  Bagny, A., Lawson-Ananissoh, L., Bouglouga, O., et al. (2019) Characteristics and Prognosis of Patients with Hepatocellular Carcinoma at Campus Teaching Hospital of Lome. Open Journal of Gastroenterology, 9, 203-210.
https://doi.org/10.4236/ojgas.2019.911023
[12]  Tao, I., Compaoré, T.R., Diarra, B., et al. (2014) Seroepidemiology of Hepatitis B and C Viruses in the General Population of Burkina Faso. Hepatitis Research and Treatment, 2014, E781843.
https://doi.org/10.1155/2014/781843
[13]  Ilunga, A.K.K., Inkale, C.B., Kilara, T., et al. (2023) Blood Safety in the Democratic Republic of the Congo: Literature Review. Open Journal of Blood Diseases, 13, 102-120.
https://doi.org/10.4236/ojbd.2023.133013
[14]  Diallo, S., Fall, M.P., Bassène, M.L., et al. (2022) Hepatitis C: Epidemiological, Clinical and Therapeutic Aspects in Dakar (Senegal). Open Journal of Gastroenterology, 12, 98-106.
https://doi.org/10.4236/ojgas.2022.124010
[15]  Kilonzo, S.B., Nkandala, I., Jaka, H., et al. (2023) Antiviral Therapy Eligibility and Low Treatment Coverage among Hepatitis B Virus Infected Patients in Tanzania. Open Journal of Gastroenterology, 13, 299-312.
https://doi.org/10.4236/ojgas.2023.1310027
[16]  Toumin, C., Ibrahim, K., Mamoudou, C., et al. (2021) Clinical and Paraclinical Aspects of Chronic Viral Hepatitis B in Patients Seen in Consultation at the Internal Medicine Department of Treichville University Hospital. Health Sciences and Diseases, 22, 16-19.
https://doi.org/10.5281/hsd.v22i11.3098
[17]  Cissoko, Y., Dao, K., Dollo, I., et al. (2023) Seroprevalence of Viral Hepatitis B and C at the Gao Regional Hospital (Northern Mali). Health Sciences and Diseases, 24, 45-49.
[18]  Zemour, L., Belghitri, A., Amani, N., et al. (2021) Prognostic Factors for Viral Hepatitis B in Oran: Prediction with Cox Model. Journal of Infectious Diseases and Epidemiology, 7, 221.
https://doi.org/10.23937/2474-3658/1510221
[19]  Traoré, K.A. (2015) Aspects épidémiologiques et caractérisation moléculaire des souches du virus de l’hépatite E (VHE) au Burkina Faso.
https://theses.hal.science/tel-01249594
[20]  Kpossou, A.R., Sehounou, J., et al. (2019) Viral Hepatitis B and C: Epidemiological and Clinical Aspects at the National Hospital and University Center of Cotonou. Médecine d’Afrique Noire, 66, 12-13.
[21]  Courouce, A.M. and Pillonel, J. (1996) Estimation of risk of virus transmission in hepatitis B and C and human retrovirus via transfusion of labile blood derivatives. Transfusion Clinique et Biologique, 3, 13-18.
[22]  Fattovich, G., Bortolotti, F. and Donato, F. (2008) Natural History of Chronic Hepatitis B: Special Emphasis on Disease Progression and Prognostic Factors. Journal of Hepatology, 48, 335-352.
https://doi.org/10.1016/j.jhep.2007.11.011
[23]  Beasley, R.P., Lin, C.C. and Chien, C.S. (1981) Hepatocellular Carcinoma and Hepatitis B Virus. A Prospective Study of 22,707 Men in Taiwan Region. The Lancet, 2, 1129-1233.
https://doi.org/10.1016/S0140-6736(81)90585-7
[24]  Mallem, L., Safir, A., Amani, N., et al. (2019) Risk Factors for Hepatic Fibrosis in Chronic B Virus Carriers Monitored at Oran University Hospital. Algerian Journal of Health Sciences, 1, 21-26.
[25]  Kitab, B., Essaid, El Feydi, A., Afifi, R., et al. (2012) Variability in the Precore and Core Promoter Regions of HBV Strains in Morocco: Characterization and Impact on Liver Disease Progression. PLOS ONE, 7, e42891.
https://doi.org/10.1371/journal.pone.0042891

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