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食管癌治疗及预后相关基因研究
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Abstract:
食管癌是消化道最常见的恶性肿瘤之一。食管癌的发病率和死亡率都很高。我国是食管癌最多的新发病例国家。食管癌预后较差，对人民健康的危害严重。虽然近年来在食管癌研究和治疗领域取得了一定进展，总的5年生存率仍较低。我国食管癌发病率呈明显的地区差异，我国新疆地区发病率高于全国。中国人群食管癌的病理类型以鳞状上皮细胞癌为主。本文回顾食管癌近年的研究进展，对食管癌放疗预后相关基因进行汇总，为食管癌研究领域的预防和控制工作提供研究参考。
Esophageal cancer is one of the most common malignant tumors in the digestive tract. Its morbidity and mortality rates are high. China has the largest number of newly reported cases of esophageal cancer in the world. This disease has a poor prognosis and does serious harm to human health. De-spite the availability of various treatment modalities, the overall 5-year survival rate remains low. In China, the incidence of EC has notable difference in regions. The incidence in the Xinjiang Uygur Autonomous region is higher than the average of China. Esophageal squamous cell carcinoma re-mains the most popular esophageal cancer in China. Furthermore, this article presents a review of the research progress in recent years regarding relevant gene for treating esophageal cancer. This paper offers a helpful reference for developing a prevention and control strategy of esophageal cancer.
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