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促皮肤伤口愈合的生物材料研究进展
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Abstract:
皮肤伤口愈合是一个复杂的多阶段生物学过程，严重的皮肤损伤或患者全身健康状况不良等情况会显著降低皮肤的愈合能力，容易形成慢性创面。传统的伤口敷料功能单一，无法促进伤口愈合。近年来，生物材料由于其强大的功能，受到了广泛关注和研究。某些生物材料本身具有生物黏附、抗菌、促血管生成等作用，还可以根据需要调整生物材料的理化性质以及负载的生物活性物质，这些特点对于设计伤口敷料是有利的。目前已经研发出了许多基于生物材料的新型伤口敷料。本文将对促皮肤伤口愈合的生物材料研究进展进行综述。
Skin wound healing is a complex multi-stage biological process. Severe skin injury or poor general health of patients can significantly reduce the skin healing ability, and it is easy to form chronic wounds. Traditional wound dressings have a single function and cannot promote wound healing. In recent years, biomaterials have received extensive attention and research due to their powerful functions. Some biomaterials themselves have the effects of biological adhesion, antibacterial, and angiogenesis, and their physical and chemical properties and loaded bioactive substances can be adjusted according to needs. These characteristics are beneficial for the design of wound dressings. Many new biomaterial-based wound dressings have been developed. This article reviews the re-search progress of biomaterials for skin wound healing.
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