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肝门部胆管癌治疗现状与进展
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Abstract:
肝门部胆管癌是指一种发生在胆囊管开口以上的肝总管至左、右肝管部位的黏膜上皮癌，其起源于胆管上皮细胞的恶性肿瘤。它的早期诊断难度大，预后差，在临床治疗上还面临着不小的考验。目前肝门部胆管癌的主要治疗手段是手术治疗，而化学治疗是其辅助治疗手段。术前，需要精准评估病人的病情，充分准备，严阵以待；在手术过程中，成功治疗的关键是要保证肿瘤被安全、有效和规范的切除。综合治疗的运用，提高了病人的生存期。以肿瘤科学理念为指导，综合运用手术、化疗、靶向治疗、免疫治疗、生物治疗等多种模式，是肝门部胆管癌治疗的未来发展趋势。
Hilar cholangiocarcinoma is a kind of mucosal epithelial carcinoma that occurs from the hepatic duct opening above the gallbladder duct opening to the left and right hepatic ducts. Its early diag-nosis is difficult, the prognosis is poor, and it is still facing no small test in clinical treatment. At present, the main treatment of hilar cholangiocarcinoma is surgery, and chemotherapy is its auxil-iary treatment. Before surgery, it is necessary to accurately assess and prepare the patient's condi-tion and be fully prepared. During the operation, the key to successful treatment is to ensure the safe, effective and standardized removal of the tumor. The application of comprehensive treatment has improved the survival time of patients. Guided by the scientific concept of cancer, the compre-hensive application of surgery, chemotherapy, targeted therapy, immunotherapy, biological thera-py and other modes is the future development trend of the treatment of hilar cholangiocarcinoma.
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