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Medical Diagnosis 2024
粒细胞集落刺激因子在生殖领域的应用
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Abstract:
胚胎植入的成功需要植入胚胎与宿主子宫内膜之间复杂的生物学相互作用，在这一复杂的过程中涉及到大量的分子和因子。粒细胞集落刺激因子(G-CSF)被证实在妊娠过程中发挥着多种生理作用，然而，目前对于G-CSF对妊娠的影响尚无统一定论。本文综述了G-CSF在生殖领域中应用的发展进程，并讨论其安全性，以期为G-CSF在临床的应用提供更为广泛的思路。
The success of embryo implantation requires complex biological interactions between the im-planted embryo and the host endometrium, which involves many molecules and factors. Granulo-cyte colony-stimulating factor (G-CSF) has been shown to play various physiological roles during pregnancy. However, there is no consensus on the effect of G-CSF on pregnancy. This article reviews the development process of the application of G-CSF in the reproductive field. It discusses its safety, to provide a broader idea for the clinical application of G-CSF.
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