Introduction:Studiesshowed a high prevalence of metabolic abnormalities including dyslipidemia,
type 2 diabetes in cases of low testosterone in men and which are associated with
increased cardiovascular risk.Hypogonadism
represents the second cause of endocrine osteoporosis. Objectives: The objectives
of our work were: to determine the main causes of hypogonadism in women and men;
to assess the frequency of metabolic and osteosdensitometric abnormalities in the
hypogonadal population. Patients and methods: A retrospective descriptive
study was carried out over 7 years on 120 patients, hospitalized in the Endocrinology
department of the Hassan II University Hospital of Fez-Morocco for hypogonadism.
The patients selected were those who had symptoms of hypogonadism confirmed in men
by: low total testosterone for Tanner stage in adolescents, <3ng/ml or
lower limit of normal for adults; in women, hypoestrogenia <30pg/l. Gonadotropin
dosage, karyotype, pelvic or testicular ultrasound and pituitary MRI, for etiological
diagnosis, were performed. Bone densitometry was performed for bone impact and lipid
profile for metabolic profile. Results:Out of 120 patients, there were 77 women and 43 men.
The average age was 31.51 years. In men, the main causes were central hypogonadism
in 67.4% and primary testicular failure in 32.6%. In women, central hypogonadism
was also the most common cause noted in 63.7% and premature ovarian failure was
observed in 36.4%.HypoHDL was significantly
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