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结直肠恶性肿瘤病人合并糖尿病与否预后的差异
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Abstract:
结直肠癌是消化系统的恶性肿瘤之一，在我国的发病率及死亡率呈逐渐上升的趋势，严重危害人们的健康。糖尿病是一种以高血糖为特征的代谢性疾病，是由于胰岛素分泌缺陷或其生物作用受损，或两者兼有引起，可导致各种组织的慢性损害及功能障碍。而合并糖尿病的结直肠恶性肿瘤病人预后更差。本篇综述重点说明了合并糖尿病的患者从生存期，发生机制，其他器官及营养状态几个方面与没有糖尿病的结直肠癌患者进行对比，说明二者预后的差异。
Colorectal cancer is one of the malignant tumors of the digestive system. In our country, the mor-bidity and mortality show a gradually rising trend. It does great harm to people’s health. Diabetes is a metabolic disease characterized by high blood sugar, which is caused by defective insulin secre-tion or impaired biological action, or both, and can lead to chronic damage and dysfunction of vari-ous tissues. The prognosis of colorectal cancer patients with diabetes mellitus is worse. This review focuses on the comparison of survival time, pathogenesis, other organs and nutritional status of pa-tients with colorectal cancer with and without diabetes, indicating the difference in prognosis be-tween the two patients.
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