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特鲁索综合征一例并文献复习
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Abstract:
特鲁索综合征(Trousseau’s syndrome)为一组以深静脉血栓为主要临床表现的综合征,是恶性肿瘤合并血栓中最常见的一种并发症,最常见的有包括静脉血栓栓塞(venous thromboembolism, VTE)、动脉血栓栓塞(arterial thromboembolism, ATE)和弥散性血管内凝血,增加了肿瘤患者的死亡率。可与恶性肿瘤先后发生,目前发病机制尚未明确,治疗上可予低分子肝素抗凝,预后多不良。本文报道1例肺癌患者突发梗死致肢体无力的病例,并结合相关文献,总结肺癌相关脑卒中临床特征,探讨该病早期诊疗价值,以期临床上尽早诊断及治疗。
Trousseau’s syndrome is a group of syndromes with deep venous thrombosis as the main clinical manifestation. It is the most common complication of malignant tumor complicated with throm-bosis. The most common complications include venous thromboembolism (VTE), arterial throm-boembolism (ATE) and disseminated intravascular coagulation, which increase the mortality of tu-mor patients. It can occur successively with malignant tumors. At present, the pathogenesis is not clear. Low molecular weight heparin anticoagulation can be used in the treatment, and the progno-sis is poor. This article reported a case of limb weakness caused by sudden infarction in a patient with lung cancer. Combined with relevant literature, the clinical characteristics of lung can-cer-related stroke were summarized, and the value of early diagnosis and treatment of the disease was discussed in order to diagnose and treat it as soon as possible.
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