Background and objective: Chronic rhinosinusitis (CRS), a common disease worldwide, has a major impact on patients’ quality of life (QoL). In recent years, the measurement of health-related QoL has made it possible to assess the patient’s state of health, the severity of the CRS and the treatment. The aim of this study was to assess the QoL of patients with CRS in a hospital setting in Kinshasa. Methods: This was a cross-sectional analytical study conducted from June 2020 to May 2021 in the ENT service of the Kinshasa University Hospital and the Monkole Hospital Center. The study involved 113 patients aged at least 18 years, whose QOL was compared with that of a control group consisting of 100 non-patients. QOL was assessed using the Sino-Nasal Outcome Test (SNOT-22) Questionnaire. Results: The mean age of the patients was 41.0 years (18 - 74 years) and that of the controls was 39.1 years (19 - 77 years). More than half of the participants were university graduates. The median SNOT-22 score was 44 (14 - 78) in patients and 7 (1 - 40) in controls. Compared with subjects without CRS, patients with CRS had significantly higher scores in all four domains of the SNOT-22. Around 9 out of 10 patients had a severely impaired QoL compared with 2 out of 10 controls. Considering mildly impaired QoL, we found that in the otological and sleep domains, scores were not significantly different between patients and controls. In the case of severely impaired QoL, however, only the otological domain showed a non-significant difference in scores between the two groups. Conclusion: CRS is a real public health problem in our environment and significantly alters the QoL of patients suffering from it, with repercussions on their professional productivity; hence the need for better management.
References
[1]
Fokkens, W., Lund, V., Mullol, J., Bachert, C., et al. (2012) European Position Paper on Rhinosinusitis and Nasal Polyps 2012. Rhinology Supplement, 23, 1-298.
[2]
Fokkens, W., Lund, V., Hopkins, C., Hellings, P.W., et al. (2020) European Position Paper on Rhinosinusitis and Nasal Polyps 2020. Rhinology, 29, 1-464.
[3]
Desrosiers, M., Evans, G., Keith, P., Wright, D., et al. (2011) Les lignes directrices canadiennes sur la prise en charge de la rhinosinusite: Rhinosinusite chronique. Journal d’oto-rhino-laryngologie et de chirurgie cervico-faciale, 40, 168-188.
[4]
Akdis, C., Hellings, P. and Agache, I. (2015) Global Atlas of Allergic Rhinitis and Chronic Rhinosinusitis: Chronic Rhinosinusitis. European Academy of Allergy and Clinical Immunology, 283-365.
[5]
DeConde, A.S. and Soler, Z.M. (2016) Chronic Rhinosinusitis: Epidemiology and Burden of Disease. American Journal of Rhinology and Allergy, 30, 134-139. https://doi.org/10.2500/ajra.2016.30.4297
[6]
Hirsch, A., Stewart, W., Sundaresan, A., Young, A., et al. (2017) Nasal and Sinus Symptoms and Chronic Rhinosinusitis in a Population-Based Sample. Allergy, 72, 274-281. https://doi.org/10.1111/all.13042
[7]
Hastan, D., Fokkens, W.J., Bachert, C., Newson, R.B., et al. (2011) Chronic Rhinosinusitis in Europe—An Underestimated Disease. A GA2LEN Study. Allergy, 66, 1216-1223. https://doi.org/10.1111/j.1398-9995.2011.02646.x
[8]
Kim, Y., Kim, N., Seong, S., Kim, K.R., Lee, G. and Kim, K.S. (2011) Prevalence and Risk Factors of Chronic Rhinosinusitis in Korea. American Journal of Rhinology and Allergy, 25, 117-121. https://doi.org/10.2500/ajra.2011.25.3630
[9]
Shi, J.B., Fu, Q.L., Zhang, H., Cheng, L., et al. (2015) Epidemiology of Chronic Rhinosinusitis: Results from a Cross-Sectional Survey in Seven Chinese Cities. Allergy, 70, 533-539. https://doi.org/10.1111/all.12577
[10]
Pilan, R., Pinna, F., Bezerra, T.F., Mori, R.L., et al. (2012) Prevalence of Chronic Rhinosinusitis in Sao Paulo. Rhinology, 50, 129-138. https://doi.org/10.4193/Rhino11.256
[11]
Homood, M.A., Alkhayrat, S.M., Kulaybi, K.M., Mohajer, A.A., et al. (2017) Prevalence and Risk Factors of Chronic Sinusitis among People in Jazan Region’ KSA. The Egyptian Journal of Hospital Medicine, 69, 2463-2468. https://doi.org/10.12816/0041695
[12]
Mainasara, M.G., Labaran, A.S., Kirfi, A.M., Fufore, M.B., et al. (2015) Clinical Profile and Management of Chronic Rhinosinusitis among Adults in North-Western Nigeria. The American Journal of Innovative Research and Applied Sciences, 1, 133-136.
[13]
Abrahama, Z.S., Gabriel, R., Kahinga, A.A., Ntunaguzi, D., et al. (2019) Prevalence of Chronic Rhinosinusitis at Muhimbili National Hospital, Dar es Salaam. South Sudan Medical Journal, 12, 97-100.
[14]
Sabwe, M., Lungungu, K. and Ndungi, M. (1999) Les sinusites: Evaluation de la fréquence et des moyens de prise en charge thérapeutique. Congo Médical, 2, 869-874.
[15]
Campbell, A.P., Hoehle, L.P., Phillips, K.M., Caradonna, D.S., et al. (2018) Le contrôle des symptômes dans la rhinosinusite chronique est un facteur prédictif indépendant de la baisse de productivité. Annales françaises d’oto-rhino-laryngologie et de pathologie cervico-faciale, 135, 230-234. https://doi.org/10.1016/j.aforl.2018.04.002
[16]
Schalek, P. (2011) Rhinosinusitis—Its Impact on Quality of Life. In: Marseglia, G.L. and Caimmi, D.P., Eds., Peculiar Aspects of Rhinosinusitis, IntechOpen, London, 112. https://doi.org/10.5772/25349
[17]
Pham, L.D., Vo, T.Q., Nguyen, H.B., Pham, A.T., et al. (2019) Assessment of Cost of Illness and Quality of Life in Chronic Rhinosinusitis Patients with Surgical Treatment. Health Economics and Community-Oriented Practice in Vietnam, 69, 10-19.
[18]
Charafeddine, R. (2014) Qualité de vie liée à la santé. Enquête de santé 2013. Rapport 1: Santé et Bien-être. WIV-ISP, Bruxelles, 1019-1049.
[19]
Segrestan, C. (2005) Score de qualité de vie: Indicateurs. https://www.afidtn.com>909_template
[20]
Klonaris, D., Doulaptsi, M., Karatzanis, A., Velegrakis, S., et al. (2019) Assessing Quality of Life and Burden of Disease in Chronic Rhinosinusitis: A Review. Rhinology Online, 2, 6-13. https://doi.org/10.4193/RHINOL/18.067
[21]
Lange, B., Holst, R., Thilsing, T., Baelum, J. and Kjeldsen, A. (2013) Quality of Life and Associated Factors in Persons with Chronic Rhinosinusitis in the General Population. Clinical Otolaryngology, 38, 474-480. https://doi.org/10.1111/coa.12189
[22]
Marambaia, P., Lima, M., Santos, K., Gomes, A., et al. (2013) Evaluation of the Quality of Life of Patients with Chronic Rhinosinusitis by Means of the SNOT-22 Questionnaire. Brazilian Journal of Otorhinolaryngology, 79, 54-58. https://doi.org/10.5935/1808-8694.20130010
[23]
Kim, D.H., Han, K. and Kim, S.W. (2016) Effect of Chronic Rhinosinusitis with or without Nasal Polyp on Quality of Life in South Korea: 5th Korea National Health and Nutrition Examination Survey Korean. Clinical and Experimental Otorhinolaryngology, 9, 150-156. https://doi.org/10.21053/ceo.2015.01053
[24]
Nyaiteera, V., Nakku, D., Nakasagga, E., Llovet, E., et al. (2018) The Burden of Chronic Rhinosinusitis and Its Effect on Quality of Life among Patients Re-Attending an Otolaryngology Clinic in South Western Uganda. BMC Ear, Nose and Throat Disorders, 18, Article No. 10. https://doi.org/10.1186/s12901-018-0058-z
[25]
Kosugi, E.M., Chen, V.G., Fonseca, V.M.G., Cursino, M.M.P., Mendes Neto, J.A. and Gregório, L.C. (2011) Translation, Cross-Cultural Adaptation and Validation of SinoNasal Outcome Test (SNOT): 22 to Brazilian Portuguese. Brazilian Journal of Otorhinolaryngology, 77, 663-669. https://doi.org/10.1590/S1808-86942011000500021
[26]
Hopkins, C., Gillett, S., Slack, R., Lund, V.J. and Browne, J.P. (2009) Psychometric Validity of the 22-Item Sinonasal Outcome Test. Clinical Otolaryngology, 34, 447-454. https://doi.org/10.1111/j.1749-4486.2009.01995.x
[27]
Idugboe, O.J., Adeyemo, A. and Totyen, L.E. (2019) The Correlation between SNOT-22 and Visual Analogue Scale in the Assessment of Symptom Severity in Chronic Rhinosinusitis. International Journal of Otorhinolaryngology, 5, 24-30. https://doi.org/10.11648/j.ijo.20190501.16
[28]
Alobid, I., Bernal-Sprekelsen, M. and Mullol, J. (2008) Chronic Rhinosinusitis and Nasal Polyps: The Role of Generic and Specific Questionnaires on Assessing Its Impact on Patient’s Quality of Life. Allergy, 63, 1267-1279. https://doi.org/10.1111/j.1398-9995.2008.01828.x
[29]
Dorlodot, C., Horoi, M., Lefebvre, P., Collet, S., et al. (2015) French Adaptation and Validation of the Sino-Nasal Outcome Test-22: A Prospective Cohort Study on Quality of Life among 422 Subjects. Clinical Otolaryngology, 40, 29-35. https://doi.org/10.1111/coa.12315
[30]
Levy, J.M., Mace, J.C., Rudmik, L., Soler, Z.M. and Smith, T.L. (2017) Low SNOT-22 Scores in Chronic Rhinosinusitis: Why Do Patients Seek Treatment? Laryngoscope, 127, 22-28. https://doi.org/10.1002/lary.26157
[31]
Njifou, N.A., Mfe Ndongo, B.L., Kuiffo, C. and Mpessa, E.M. (2018) Les Rhinosinusites Chroniques à l’Hôpital Laquintinie de Douala. Health Sciences and Diseases, 19, 99-103.
[32]
Bewick, J., Morris, S., Hopkins, C., Erskine, S. and Philpott, C.M. (2018) Health Utility Reporting in Chronic Rhinosinusitis Patients. Clinical Otolaryngology, 43, 90-95. https://doi.org/10.1111/coa.12903
[33]
Philpott, C., Erskine, S., Hopkins, C., Coombes, E., et al. (2016) A Case-Control Study of Medical, Psychological and Socioeconomic Factors Influencing the Severity of Chronic Rhinosinusitis. Rhinology, 54, 134-140. https://doi.org/10.4193/Rhino15.272
[34]
Hoehle, L.P., Phillips, K.M., Bergmark, R.W., Caradonna, D.S., et al. (2016) Symptoms of Chronic Rhinosinusitis Differentially Impact General Health-Related Quality of Life. Rhinology, 54, 316-322. https://doi.org/10.4193/Rhino16.211
[35]
Lange, B., Thilsing, T., Baelum, J. and Kjeldsen, A.D. (2016) The Sinonasal Outcome Test 22 Score in Persons without Chronic Rhinosinusitis. Clinical Otolaryngology, 41, 127-130. https://doi.org/10.1111/coa.12481
[36]
Yeolekar, A.M., Dasgupta, K.S., Khode, S., Joshi, D. and Gosrani, N. (2013) A Study of SNOT 22 Scores in Adults with No Sinonasal Disease. Journal of Rhinolaryngo-Otologies, 1, 6-10. https://doi.org/10.12970/2308-7978.2013.01.01.2
[37]
Gillett, S., Hopkins, C., Slack, R. and Browne, J.P. (2009) A Pilot Study of the SNOT 22 Score in Adults with No Sinonasal Disease. Clinical Otolaryngology, 34, 467-469. https://doi.org/10.1111/j.1749-4486.2009.01975.x
