Castleman’s disease (CH) is a rare chronic lymphoproliferative disease whose etiology is often unclear and whose definitive diagnosis can be made immunopathologically. CH was first described by Castleman et al. in 1956 as a non-lymphoproliferative disease. It can be easily misdiagnosed as a gastrointestinal stromal tumor (GIST), which is submucosal in the abdomen, especially when found in the perigastric area. Although patients are often asymptomatic, the diagnosis is usually made by abdominal ultrasonography (USG) and computer tomography (CT) performed for routine screening. Preoperative diagnosis is very difficult due to nonspecific imaging findings and rarity. In our patient who was diagnosed with CH after USG, CT, EUS (endoscopic ultrasonography) and laparoscopic excision and immunopathological analysis, we see the contribution of EUS to our diagnosis in the preoperative period in addition to routine diagnostic tests.
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