All Title Author
Keywords Abstract

Publish in OALib Journal
ISSN: 2333-9721
APC: Only $99


Relative Articles


Fate and Behavior of Tetracycline Resistance Genes in Activated Carbon Adsorption

DOI: 10.4236/jwarp.2024.161001, PP. 1-16

Keywords: Antibiotic Resistance Genes, Adsorption, Activated Carbon, Drinking Water Treatment

Full-Text   Cite this paper   Add to My Lib


The accessibility of tetracycline resistance gene (tetG) into the pores of activated carbon (AC), as well as the impact of the pore size distribution (PSD) of AC on the uptake capacity of tetG, were investigated using eight types of AC (four coal-based and four wood-based). AC showed the capability to admit tetG and the average reduction of tetG for coal-based and wood-based ACs at the AC dose of 1 g·L-1 was 3.12 log and 3.65 log, respectively. The uptake kinetic analysis showed that the uptake of the gene followed the pseudo-second-order kinetics reaction, and the uptake rate constant for the coal-based and wood-based ACs was in the range of 5.97 × 10-12 - 4.64 × 10-9 and 7.02 × 10-11 - 1.59 × 10-8 copies·mg-1·min-1, respectively. The uptake capacity analysis by fitting the obtained experiment data with the Freundlich isotherm model indicated that the uptake constant (KF) values were 1.71 × 103 - 8.00 × 109 (copies·g-1)1-1/n for coal-based ACs and 7.00 × 108 - 3.00 × 1010 (copies·g-1)1-1/n for wood-based ones. In addition, the correlation analysis between KF values and pore volume as well as pore surface at different pore size regions of ACs showed that relatively higher positive correlation was found for pores of 50 - 100 Å, suggesting ACs with more pores in this size region can uptake more tetG. The findings of this study are valuable as reference for optimizing the adsorption process regarding antibiotic resistance-related concerns in drinking water treatment.


[1]  Li, S., Zhang, C., Li, F., Hua, T., Zhou, Q. and Ho, S.-S. (2021) Technologies towards Antibiotic Resistance Genes (ARGs) Removal from Aquatic Environment: A Critical Review. Journal of Hazardous Materials, 411, Article 125148.
[2]  Davies, J. and Davies, D. (2010) Origins and Evolution of Antibiotic Resistance. Microbiology and Molecular Biology Reviews, 74, 417-433.
[3]  Li, B., Qiu, Y., Song, Y., Lin, Y., Lin, H. and Yin, H. (2019) Dissecting Horizontal and Vertical Gene Transfer of Antibiotic Resistance Plasmid in Bacterial Community using Microfluidics. Environment International, 131, Article 105007.
[4]  Kumar, S.B., Arnipalli, S.R. and Ziouzenkova, O. (2020) Antibiotics in Food Chain: The Consequences for Antibiotic Resistance. Antibiotics, 9, Article 688.
[5]  Tian, Y., Yao, S., Zhou, L., Hu, Y., Lei, J., Wang, L., Zhang, J., Liu, Y. and Zui, C. (2022) Efficient Removal of Antibiotic-Resistant Bacteria and Intracellular Antibiotic Resistance Genes by Heterogeneous Activation of Peroxymonosulfate on Hierarchical Macro-Mesoporous Co3O4-SiO2 with Enhanced Photogenerated Charges. Journal of Hazardous Materials, 430, Article 127414.
[6]  Sanganyado, E. and Gwenzi, W. (2019) Antibiotic Resistance in Drinking Water Systems: Occurrence, Removal, and Human Health Risks. Science of the Total Environment, 669, 785-797.
[7]  Chu, G., Qi, W., Chen, W., Zhang, Y., Gao, S., Wang, Q., Gao, C. and Gao, M. (2024) Metagenomic Insights into the Nitrogen Metabolism, Antioxidant Pathway, and Antibiotic Resistance Genes of Activated Sludge from a Sequencing Batch Reactor under Tetracycline Stress. Journal of Hazardous Materials, 462, Article 132788.
[8]  Chen, J., Su, Z., Dai, T., Huang, B., Mu, Q., Zhang, Y. and Wen, D. (2019) Occurrence and Distribution of Antibiotic Resistance Genes in the Sediments of the East China Sea bays. Journal of Environmental Sciences, 81, 156-167.
[9]  Lu, J., Zhang, Y., Wu, J., Wang, J., Zhang, C. and Lin, Y. (2019) Occurrence and Spatial Distribution of Antibiotic Resistance Genes in the Bohai Sea and Yellow Sea Areas, China. Environmental Pollution, 252, 450-460.
[10]  Cheng, J., Yang, Y., Liu, Y., Tang, M., Wang, R., Tian, Y. and Jia, C. (2019) Bacterial Community Shift and Antibiotics Resistant Genes Analysis in Response to Biodegradation of Oxytetracycline in Dual Graphene Modified Bioelectrode Microbial Fuel Cell. Bioresource Technology, 276, 236-243.
[11]  Jones, R.N., Flonta, M., Gurler, N., Cepparulo, M., Mendes, R. and Castanheira, M. (2014) Resistance Surveillance Program Report for Selected European Nations (2011). Diagnostic Microbiology and Infectious Disease, 78, 429-436.
[12]  Zhang, L., Ji, L., Liu, X., Zhu, X., Ning, K. and Wang, Z. (2022) Linkage and Driving Mechanisms of Antibiotic Resistome in Surface and Ground Water: Their Responses to Land Use and Seasonal Variation. Water Research, 215, Article 118279.
[13]  Huang, L., Xu, Y., Xu, J., Ling, J., Zheng, L., Zhou, X. and Xie, G. (2019) Dissemination of Antibiotic Resistance Genes (ARGs) by Rainfall on a Cyclic Economic Breeding Livestock Farm. International Biodeterioration & Biodegradation, 138, 114-121.
[14]  Szekeres, E., Baricz, A., Chiriac, C.M., Farkas, A., Opris, O., Soran, M.-L., Andrei, A.-S., Rudi, K., Balcázar, J.L., Dragos, N. and Coman, C. (2017) Abundance of Antibiotics, Antibiotic Resistance Genes and Bacterial Community Composition in Wastewater Effluents from Different Romanian Hospitals. Environmental Pollution, 225, 304-315.
[15]  Rafraf, I.D., Lekunberri, I., Sànchez-Melsió, A., Aouni, M., Borrego, C.M. and Balcázar, J.L. (2016) Abundance of Antibiotic Resistance Genes in Five Municipal Wastewater Treatment Plants in the Monastir Governorate, Tunisia. Environmental Pollution, 219, 353-358.
[16]  Su, H.-C., Liu, Y.-S., Pan, C.-G., Chen, J., He, L.-Y. and Ying, G.-G. (2018) Persistence of Antibiotic Resistance Genes and Bacterial Community Changes in Drinking Water Treatment System: From Drinking Water Source to Tap Water. Science of the Total Environment, 616-617, 453-461.
[17]  Xu, L., Canales, M., Zhou, Q., Karu, K., Zhou, X., Su, J., Campos, L.C. and Ciric, L. (2023) Antibiotic Resistance Genes and the Association with Bacterial Community in Biofilms Occurring during the Drinking Water Granular Activated Carbon (GAC) Sandwich Biofiltration. Journal of Hazardous Materials, 460, Article 132511.
[18]  Hu, Y., Zhang, T., Jiang, L., Luo, Y., Yao, S., Zhang, D., Lin, K. and Cui, C. (2019) Occurrence and Reduction of Antibiotic Resistance Genes in Conventional and Advanced Drinking Water Treatment Processes. Science of the Total Environment, 669, 777-784.
[19]  Anggreini, S., Rosadi, M.Y., Yamada, T., Hudori, H., Deng, Z. and Li, F. (2023) Characteristics of Organic Matter released from Drinking Water Treatment Sludge under Different Storage Conditions: Evaluation Based on Activated Carbon Adsorbability. Chemosphere, 339, Article 139679.
[20]  Li, F., Yuasa, A., Chiharada, H. and Matsui, Y. (2003) Polydisperse Adsorbability Composition of Several Natural and Synthetic Organic Matrices. Journal of Colloid and Interface Science, 265, 265-275.
[21]  Ebie, K., Li, F., Azuma, Y., Yuasa, A. and Hagishita, T. (2001) Pore Distribution Effect of Activated Carbon in Adsorbing Organic Micropollutants from Natural Water. Water Research, 35, 167-179.
[22]  Golea, D.M., Jarvis, P., Jefferson, B., Moore, G., Sutherland, S., Parsons, S.A. and Judd, S.J. (2020) Influence of Granular Activated Carbon Media Properties on Natural Organic Matter and Disinfection By-Product Precursor Removal from Drinking Water. Water Research, 174, Article 115613.
[23]  Sun, L., Ding, Y., Yang, B., He, N. and Chen, T. (2020) Effect of Biological Powdered Activated Carbon on Horizontal Transfer of Antibiotic Resistance Genes in Secondary Effluent. Environmental Engineering Science, 37, 365-372.
[24]  Sun, L., Shi, P., He, N., Zhang, Q. and Duan, X. (2019) Antibiotic Resistance Genes Removal and Membrane Fouling in Secondary Effluents by Combined Processes of PAC/BPAC-UF. Journal of Water and Health, 17, 910-920.
[25]  Li, F., Yuasa, A., Ebie, K., Azuma, Y., Hagishita, T. and Matsui, Y. (2002) Factors Affecting the Adsorption Capacity of Dissolved Organic Matter onto Activated Carbon: Modified Isotherm Analysis. Water Research, 36, 4592-4604.
[26]  Tan, Y.L., Islam, M.A., Asif, M. and Hameed, B.H. (2014) Adsorption of Carbon Dioxide by Sodium Hydroxide-Modified Granular Coconut Shell Activated Carbon in a Fixed Bed. Energy, 77, 926-931.
[27]  Li, W., Li, J., Bhat, S.A., Wei, Y., Deng, Z. and Li, F. (2021) Elimination of Antibiotic Resistance Genes from Excess Activated Sludge Added for Effective Treatment of Fruit and Vegetable Waste in a Novel Vermireactor. Bioresource Technology, 325, 124695.
[28]  Agarwal, S. and Rani, A. (2017) Adsorption of Resorcinol from Aqueous Solution onto CTAB/NaOH/Flyash Composites: Equilibrium, Kinetics and Thermodynamics. Journal of Environmental Chemical Engineering, 5, 526-538.
[29]  Li, S., Li, Z., Ke, B., He, Z., Cui, Y., Pan, Z., Li, D., Huang, S., Lai, C. and Su, J. (2019) Magnetic Multi-Walled Carbon Nanotubes Modified with Polyaluminium Chloride for Removal of Humic Acid from Aqueous Solution. Journal of Molecular Liquids, 279, 241-250.
[30]  Li, N., Ma, X., Zha, Q., Kim, K., Chen, Y. and Song, C. (2011) Maximizing the Number of Oxygen-Containing Functional Groups on Activated Carbon by using Ammonium Persulfate and Improving the Temperature-Programmed Desorption Characterization of Carbon Surface Chemistry. Carbon, 49, 5002-5013.
[31]  Yu, W., Zhan, S., Shen, Z., Zhou, Q. and Yang, D. (2017) Efficient Removal Mechanism for Antibiotic Resistance Genes from Aquatic Environments by Graphene Oxide Nanosheet. Chemical Engineering Journal, 313, 836-846.
[32]  Varga, M., ELAbadsa, M., Tatár, E. and Mihucz, V.G. (2019) Removal of Selected Pharmaceuticals from Aqueous Matrices with Activated Carbon under Batch Conditions. Microchemical Journal, 148, 661-672.
[33]  Kalam, S., Abu-Khamsin, S.A., Kamal, M.S. and Patil, S. (2021) Surfactant Adsorption Isotherms: A Review. ACS Omega, 6, 32342-32348.
[34]  Pelekani, C. and Snoeyink, V.L. (1999) Competitive Adsorption in Natural Water: Role of Activated Carbon Pore Size. Water Research, 33, 1209-1219.
[35]  Hu, Z. and Srinivasan, M.P. (2001) Mesoporous High-Surface-Area Activated Carbon. Microporous and Mesoporous Materials, 43, 267-275.


comments powered by Disqus

Contact Us


WhatsApp +8615387084133

WeChat 1538708413