Introduction: Venous thromboembolism (VTE) is a nosological group which mainly
includes deep vein thrombosis (DVT) and pulmonary embolism (PE), it is
frequently associated with high morbidity and mortality. We initiated this
study with the aim of studying VTE in a cardiological hospital environment in a
regional hospital in Mali. Methodology: This was a descriptive study
with prospective recruitment over 1 year from June 20, 2019 to June 20, 2020,
covering patients hospitalized and followed in consultation in the cardiology
department of the Ségou regional hospital in Mali. Results:We collected 31 cases of VTE out of 366 patients, representing a frequency of 8.47%. The sex ratio was 0.88. VTE risk factors were dominated by
immobilization (29.03%), pregnancy and postpartum (16.12%), heart failure
(16.12%). The reason for consultation was dyspnea (93.54%) followed by chest
pain (83.87%). On admission the clinical manifestations were
tachycardia (74.19%), tachypnea (90.32%), muffled heart sounds (70.96%), global
heart failure syndrome (51.6%).
According to VTE probability scores; 51.61% of patients had an intermediate
clinical probability according to the simplified Wells score for PE and 54.84%
had an intermediate clinical probability for the simplified Geneva score for
DVT. D-Dimers were only performed in 12 patients (38.70%) and were elevated in
all. A chest CT angiogram showed PE in 90% of patients (n = 28/31). Venous
Doppler ultrasound of the lower limbs showed venous thrombosis in 3 patients. Conclusion: Venous thromboembolism, although underdiagnosed, is common in our health
structures. Prevention, particularly heparinoprophylaxis and early recovery in
a hospital environment, remains the effective means of combating this
condition.
References
[1]
Caillard, G. and Clerel, M. (2001) Travel ant Risk of Venous Thrombosis. Lancet, 357, 554-555. https://doi.org/10.1016/S0140-6736(05)71698-6
[2]
Owono Etoundi, P., Esiéne, A., Bengono Bengono, R., Amengle, L., Afane Ela, A. and Ze Minkande. J. (2015) Venous Thromboembolic Disease. Epidemiological Aspects and Risk Factors in a Cameroonian Hospital. Health Sciences and Diseases, 16, 1-4.
[3]
Prandoni, P. (2008) Prevention and Treatment of Venous Thromboembolism with Low Molecular Weight Heparins: Clinical Implications of the Recent European Guidelines. Thrombosis Journal, 6, Article No. 13.
https://doi.org/10.1186/1477-9560-6-13
[4]
Goldhaber, S.Z. (2012) Venous Thromboembolism: Epidemiology and Magnitude of the Problem. Best Practice & Research Clinical Haematology, 25, 235-242.
https://doi.org/10.1016/j.beha.2012.06.007
[5]
Bertnard, E., Charle, D., Chouvet, J., Coulibaly, A.O., Ekkra, A., Kerfelec, I., et al. (1979) On the Rarity of Thromboembolic Pathology in Tropical Regions. Summary of Tropical Cardiovascular Pathology, Paris, 319 p.
[6]
Bertnard, E, Charle, D., Chouvet, J., Coulibaly, A.O., Ekkra, A. and Renambot, J. (1989) Venous Thrombosis of the Lower Limbs. Summary of Tropical Cardiovascular Pathologies by Sandoz Editions, Paris, 322 p.
[7]
Coulibaly, S., Menta, I., Diall, I.B., Ba, O.H., Diakité, M., Sidibé, S., et al. (2018) Venous Thromboembolic Disease in the Cardiology Department of Point G University Hospital in Bamako. Health Sciences and Diseases, 19, 27-30.
[8]
Menta, I., Walbane, M., Ba, H.O., Traore, D., Coulibaly, S., Camara, Y., Sangare, I., Diall, I.B., Sidibe, S., Sidibe, N., Diakite, M., Thiam, C., Toure, K. and Sanogo, K. (2019) Deep Venous Thrombosis in Hospitalization in the Department of Cardiology of the Gabriel Touré University Hospital. Annals of Vascular Medicine, 2, 1-4.
[9]
Camara, Y., Ba, H.O., Sangaré, I., Sidibé, N., Thiam ep Doumbia, C., Kéita ep Maiga, A., et al. (2022) Thromboembolic Disease: Epidemioclinical and Therapeutic Aspects at Kati University Hospital. Health Sciences and Diseases, 22, 86-89.
[10]
Ello, F.N., Bawe, L.D., Kouakou, G.A., Mossou, C.M., Adama, D., Kassi, A.N., et al. (2018) Thromboembolic Manifestations in 36 West African Patients Infected with HIV. Pan African Medical Journal, 31, 1-9.
[11]
Diall, I.B., Coulibaly, S., Minta, I., Ba, H., Diakite, M., Sidibe, N., Sangare, I., Diakite, S., Sanogo, K. and Diallo, B.A. (2011) Etiology, Clinic and Evolution of Pulmonary Embolism in 30 Cases. Mali Medical, 26, 1-4.
[12]
Le Gal, G., Righini, M., Roy, P.M., et al. (2005) Differential Value of Risk Factors and Clinical Signs for Diagnosing Pulmonary Embolism According to Age. Journal of Thrombosis and Haemostasis, 3, 2457-2464.
https://doi.org/10.1111/j.1538-7836.2005.01598.x
[13]
Goldhaber, S.Z., Visani, L. and De Rosa, M. (1999) Acute Pulmonary Embolism: Clinical Outcomes in the International Cooperative Pulmonary Embolism Registry (ICOPER). Lancet, 353, 1386-1389. https://doi.org/10.1016/S0140-6736(98)07534-5
[14]
Menta, I., Ba, H.O., Fofana, C.A., Sidibé, N., Sogodogo, A. and Sanogo, K.M. (2015) Thrombophlebitis of Limbs in the Cardiology Department of the Gabriel Touré University Hospital. Mali Medical, 30, 3-6.
[15]
Damorou, F., Baragou, S., Pio, M., Afassinou, Y.M., N’da, N.W., Pessinaba, S., Tchérou, T., Attiogbé, H., Ehlan, K., Goeh-Akue, E. and Yayehd, K. (2014) Morbidity and Hospital Mortality from Cardiovascular Diseases in a Tropical Environment: Example of a Hospital Center in Lomé (Togo). The Pan African Medical Journal, 17, Article 62. https://doi.org/10.11604/pamj.2014.17.62.2237