Celosia L. is richly distributed in China and there are
about 60 species in the world. The chemical constituents of Celosia L.
include flavonoids, triterpenoid saponins, steroids, organic acids, and cyclic
peptides. Which have a variety of effects such as antimicrobial,
hepatoprotective and antitumour. To provide a scientific foundation for the
subsequent phase of research and development for Celosia L.,30 years of pertinent global literature is
summarized, analyzed, and categorized. An overview of 75 chemical constituents,
pharmacological activities, and clinical applications is provided.
References
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Zhang, T. (2013) Research on the Chemical Composition of Celosia cristata L. Thesis, Heilongjiang University of Traditional Chinese Medicine, Harbin.
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Li, X., Huang, B., Tan, G., et al. (2023) Comparison of Different Extraction Methods of Total Flavonoids from Celosia cristata L. Guangdong Chemical Industry, 50, 68-72.
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Wang, J., Zhang, X. and Huang, Z. (2008) Simultaneous Determination of Quercetin, Lignans and Kaempferol in Celosia cristata L. by RP-HPLC. Northwest Journal of Pharmacy, 6, 354-356.
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Wen, Y., Islam, M.T. and Tahara, S. (2006) Phenolic Constituents of Celosia cristata L: Susceptible to Spinach Root Rot Pathogen Aphanomyces cochlioides. Bioscience, Biotechnology, and Biochemistry, 70, 2567-2570. https://doi.org/10.1271/bbb.60272
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Wang, Y., Lou, Z., Wu, Q., et al. (2010) A Novel Hepatoprotective Saponin from Celosia cristata L. Fitoterapia, 81, 1246-1252. https://doi.org/10.1016/j.fitote.2010.08.011
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Li, G., Sun, D., He, M., et al. (2020) Study on the HPLC Fingerprinting and Determination of Flavonoid Content of Celosia cristata L. Journal of Traditional Chinese Medicine, 26, 64-71.
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Weng, D., Wang, H. and Weng, J. (2000) Studies on Flavonoids in the Sequence of Common Celosia cristata L. Botanical Bulletin, 6, 565-568.
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Rub, R.A., Pati, M.J., Siddiqui, A.A., et al. (2016) Characterization of Anticancer Principles of Celosia argentea L. (Amaranthaceae). Pharmacognosy Research, 8, 97-104. https://doi.org/10.4103/0974-8490.172659
[13]
Shen, S., Ding, X., Ouyang, M.A., et al. (2010) A New Phenolic Glycoside and Cytotoxic Constituents from Celosia argentea L. Journal of Asian Natural Products Research, 12, 821-827. https://doi.org/10.1080/10286020.2010.503652
[14]
Wang, Y. (2012) Research on the Chemical Composition and Biological Activity of Celosia cristata L. Seeds and Torn Root Vegetables. Thesis, Second Military Medical University, Chongqing.
[15]
Sun, Z., Gao, G., Xia, Y., et al. (2011) A New Hepoprotective Saponin from Semen Celosia cristatae. Fitoterapia, 82, 591-594. https://doi.org/10.1016/j.fitote.2011.01.007
[16]
Xue, Q., Sun, Z., Guo, M., et al. (2011) Two New Compounds from Semen Celosiae and Their Protective Effects against CCL4-Induced Hepatotoxicity. Natural Product Research, 25, 772-780. https://doi.org/10.1080/14786410902833948
[17]
Wu, Q., Wang, Y. and Guo, M. (2011) Triterpenoid Saponins from the Seeds of Celosia argentea L. and Their Anti-Inflammatory and Antitumor Activities. Chemical and Pharmaceutical Bulletin (Tokyo), 59, 666-671. https://doi.org/10.1248/cpb.59.666
[18]
Pang, X., Yan, H., Wang, Z., et al. (2014) New Oleanane-Type Triterpenoid Saponins Isolated from the Seeds of Celosia argentea L. Journal of Asian Natural Products Research, 16, 240-247. https://doi.org/10.1080/10286020.2013.879120
[19]
Feng, C., Shi, L., Chen, D., et al. (2017) Study on the Chemical Composition of Haemostatic Effective Parts of Celosia cristata L. Chinese Herbal Medicine, 48, 653-656.
[20]
Qin, T. and Zhang, J. (2021) Progress in the Study of Plant Cyclic Peptide Bioactivity and Its Mechanism of Action. Chinese Herbal Medicine, 52, 255-266.
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Guo, J., Shen, S., Zhang, X., et al. (2021) Chemical Compounds with a Neuroprotective Effect from the Seeds of Celosia argentea L. Food & Function, 12, 83-96. https://doi.org/10.1039/D0FO02033H
[22]
Xue, Q., Guo, M. and Zhang, G. (2006) Studies on the Chemical Composition of Celosia argentea L. Pharmaceutical Services and Research, No. 5, 345-347.
[23]
Morita, H., Suzuki, H. and Kobayashi, J. (2004) Celogenamide A, a New Cyclic Peptide from the Seeds of Celosia argentea L. Journal of Natural Products, 67, 1628-1630. https://doi.org/10.1021/np049858i
[24]
Suzuki, H., Morita, H., Iwasaki, S., et al. (2003) New Antimitotic Bicyclic Peptides, Celogentins D-H, and J, from the Seeds of Celosia argentea L. Tetrahedron, 59, 5307-5315. https://doi.org/10.1016/S0040-4020(03)00762-2
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Zhang, Y., Gu, Y., Zhao, R., et al. (2017) Anti-Inflammatory Effects of n-Butanol Extract of Celosia cristata L. Journal of Changchun University of Traditional Chinese Medicine, 33, 706-708.
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Deng, M., Chen, L. and He, J., (2022) Effects of Celosia cristata L. Flavonoids on TMAO/NF-κB/NFATc1 Levels in Osteoporotic Rats. Chinese Journal of Osteoporosis, 28, 1485-1490.
[47]
Jiang, X. (2005) Study on the Effect of Celosia L. diffusa on Aging Animal Models. Yunnan Journal of Traditional Chinese Medicine, 1, 33-41.
[48]
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