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Burkitt Lymphoma Presenting as Ileocolic Intussusception in an Adult

DOI: 10.4236/ojbd.2023.134014, PP. 121-132

Keywords: Burkitt Lymphoma, Adult Intussusception, Prognostication

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Abstract:

Adult intussusception is rare, highly associated with a malignant lead point, and often requires emergent surgical management. We report the case of a 44-year-old male who presented with generalized abdominal pain and was found to have early ileocolic intussusception secondary to a large ileocecal mass. Biopsies of the mass and an enlarged cardiophrenic lymph node, as well as pleural fluid cytology were all consistent with Burkitt lymphoma (BL). Curiously, the patient’s abdominal exam was reassuring, and the intussusception and malignant bowel obstruction resolved over 36 hours with conservative management alone. With a Burkitt lymphoma international prognostic index (BL-IPI) score of 2, the patient proceeded to treatment with combination chemoimmunotherapy and attained a complete response after four cycles. There was no bowel perforation or recurrent intussusception throughout treatment. Thus, this report marks the first reported case of adult BL-associated intussusception to resolve with non-invasive management and establishes a precedent for conservative management in select patients.

References

[1]  Marinis, A., Yiallourou, A., Samanides, L., Dafnios, N., Anastasopoulos, G., Vassiliou, I. and Theodosopoulos, T. (2009) Intussusception of the Bowel in Adults: A Review. World Journal of Gastroenterology, 15, 407-411.
https://doi.org/10.3748/wjg.15.407
[2]  Sarma, D., Prabhu, R. and Rodrigues, G. (2012) Adult Intussusception: A Six-Year Experience at a Single Center. Annals of Gastroenterology, 25, 128-132.
[3]  Olszewski, A.J., Jakobsen, L.H., Collins, G.P., Cwynarski, K., Bachanova, V., Blum, K.A., Boughan, K.M., Bower, M., Dalla Pria, A., Danilov, A., et al. (2021) Burkitt Lymphoma International Prognostic Index. Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology, 39, 1129-1138.
https://doi.org/10.1200/JCO.20.03288
[4]  López, C., Burkhardt, B., Chan, J.K.C., Leoncini, L., Mbulaiteye, S.M., Ogwang, M.D., Orem, J., Rochford, R., Roschewski, M. and Siebert, R. (2022) Burkitt Lymphoma. Nature Reviews Disease Primers, 8, Article No. 78.
https://doi.org/10.1038/s41572-022-00404-3
[5]  Roschewski, M., Staudt, L.M. and Wilson, W.H. (2022) Burkitt’s Lymphoma. The New England Journal of Medicine, 387, 1111-1122.
https://doi.org/10.1056/NEJMra2025746
[6]  King, R.L., Hsi, E.D., Chan, W.C., Piris, M.A., Cook, J.R., Scott, D.W. and Swerdlow, S.H. (2023) Diagnostic Approaches and Future Directions in Burkitt Lymphoma and High-Grade B-Cell Lymphoma. Virchows Archiv, 482, 193-205.
https://doi.org/10.1007/s00428-022-03404-6
[7]  Alaggio, R., Amador, C., Anagnostopoulos, I., Attygalle, A.D., Araujo, I.B.O., Berti, E., Bhagat, G., Borges, A.M., Boyer, D., Calaminici, M., et al. (2022) The 5th Edition of the World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms. Leukemia, 36, 1720-1748.
https://doi.org/10.1038/s41375-022-01620-2
[8]  Campo, E., Jaffe, E.S., Cook, J.R., Quintanilla-Martinez, L., Swerdlow, S.H., Anderson, K.C., Brousset, P., Cerroni, L., de Leval, L., Dirnhofer, S., et al. (2022) The International Consensus Classification of Mature Lymphoid Neoplasms: A Report from the Clinical Advisory Committee. Blood, 140, 1229-1253.
[9]  Teras, L.R., DeSantis, C.E., Cerhan, J.R., Morton, L.M., Jemal, A. and Flowers, C.R. (2016) 2016 US Lymphoid Malignancy Statistics by World Health Organization Subtypes. CA: A Cancer Journal for Clinicians, 66, 443-459.
https://doi.org/10.3322/caac.21357
[10]  Mbulaiteye, S.M., Anderson, W.F., Bhatia, K., Rosenberg, P.S., Linet, M.S. and Devesa, S.S. (2010) Trimodal Age-Specific Incidence Patterns for Burkitt Lymphoma in the United States, 1973-2005. International Journal of Cancer, 126, 1732-1739.
https://doi.org/10.1002/ijc.24934
[11]  Bociek, R.G. (2005) Adult Burkitt’s Lymphoma. Clinical Lymphoma, 6, 11-20.
https://doi.org/10.3816/CLM.2005.n.021
[12]  Gou, H.F., Zang, J., Jiang, M., Yang, Y., Cao, D. and Chen, X.C. (2012) Clinical Prognostic Analysis of 116 Patients with Primary Intestinal Non-Hodgkin Lymphoma. Medical Oncology, 29, 227-234.
https://doi.org/10.1007/s12032-010-9783-x
[13]  Čubranić, A., Golčić, M., Fučkar-Čupić, D., Brozović, B., Gajski, D. and Brumini, I. (2019) Burkitt Lymphoma in Gastrointestinal Tract: A Report of Two Cases. Acta Clinica Croatica, 58, 386-390.
https://doi.org/10.20471/acc.2019.58.02.25
[14]  Otter, R., Bieger, R., Kluin, P.M., Hermans, J. and Willemze, R. (1989) Primary Gastrointestinal Non-Hodgkin’s Lymphoma in a Population-Based Registry. British Journal of Cancer, 60, 745-750.
https://doi.org/10.1038/bjc.1989.351
[15]  Shirwaikar Thomas, A., Schwartz, M. and Quigley, E. (2019) Gastrointestinal Lymphoma: The New Mimic. BMJ Open Gastroenterology, 6, e000320.
https://doi.org/10.1136/bmjgast-2019-000320
[16]  Koniaris, L.G., Drugas, G., Katzman, P.J. and Salloum, R. (2003) Management of Gastrointestinal Lymphoma. Journal of the American College of Surgeons, 197, 127-141.
https://doi.org/10.1016/S1072-7515(03)00002-4
[17]  Vaidya, R., Habermann, T.M., Donohue, J.H., Ristow, K.M., Maurer, M.J., Macon, W.R., Colgan, J.P., Inwards, D.J., Ansell, S.M., Porrata, L.F., et al. (2013) Bowel Perforation in Intestinal Lymphoma: Incidence and Clinical Features. Annals of Oncology, 24, 2439-2443.
https://doi.org/10.1093/annonc/mdt188
[18]  Vaidya, R. and Witzig, T.E. (2014) Incidence of Bowel Perforation in Gastrointestinal Lymphomas by Location and Histology. Annals of Oncology, 25, 1249-1250.
https://doi.org/10.1093/annonc/mdu135
[19]  Evens, A.M., Danilov, A., Jagadeesh, D., Sperling, A., Kim, S.H., Vaca, R., Wei, C., Rector, D., Sundaram, S., Reddy, N., et al. (2021) Burkitt Lymphoma in the Modern Era: Real-World Outcomes and Prognostication across 30 US Cancer Centers. Blood, 137, 374-386.
https://doi.org/10.1182/blood.2020006926
[20]  Honjo, H., Mike, M., Kusanagi, H. and Kano, N. (2015) Adult Intussusception: A Retrospective Review. World Journal of Surgery, 39, 134-138.
https://doi.org/10.1007/s00268-014-2759-9
[21]  Yalamarthi, S. and Smith, R.C. (2005) Adult Intussusception: Case Reports and Review of Literature. Postgraduate Medical Journal, 81, 174-177.
https://doi.org/10.1136/pgmj.2004.022749
[22]  Al-Radaideh, A.M., Omari, H.Z. and Bani-Hani, K.E. (2018) Adult Intussusception: A 14-Year Retrospective Study of Clinical Assessment and Computed Tomography Diagnosis. Acta Gastro-Enterologica Belgica, 81, 367-372.
[23]  Bar-Ziv, J. and Solomon, A. (1991) Computed Tomography in Adult Intussusception. Gastrointestinal Radiology, 16, 264-266.
https://doi.org/10.1007/BF01887362
[24]  Gayer, G., Apter, S., Hofmann, C., Nass, S., Amitai, M., Zissin, R. and Hertz, M. (1998) Intussusception in Adults: CT Diagnosis. Clinical Radiology, 53, 53-57.
https://doi.org/10.1016/S0009-9260(98)80035-4
[25]  Kim, Y.H., Blake, M.A., Harisinghani, M.G., Archer-Arroyo, K., Hahn, P.F., Pitman, M.B. and Mueller, P.R. (2006) Adult Intestinal Intussusception: CT Appearances and Identification of a Causative Lead Point. Radiographics, 26, 733-744.
https://doi.org/10.1148/rg.263055100
[26]  Barussaud, M., Regenet, N., Briennon, X., de Kerviler, B., Pessaux, P., Kohneh-Sharhi, N., Lehur, P.A., Hamy, A., Leborgne, J., Le Neel, J.C., et al. (2006) Clinical Spectrum and Surgical Approach of Adult Intussusceptions: A Multicentric Study. International Journal of Colorectal Disease, 21, 834-839.
https://doi.org/10.1007/s00384-005-0789-3
[27]  Wang, L.T., Wu, C.C., Yu, J.C., Hsiao, C.W., Hsu, C.C. and Jao, S.W. (2007) Clinical Entity and Treatment Strategies for Adult Intussusceptions: 20 Years’ Experience. Diseases of the Colon & Rectum, 50, 1941-1949.
https://doi.org/10.1007/s10350-007-9048-8
[28]  Baek, D.Y., Heo, D.H., Oh, S.M., Hwang, J.H., Hwang, J.H., Park, H.S. and Lee, C.S. (2018) A Case of Jejunal Intussusception Caused by Burkitt Lymphoma in an Acquired Immunodeficiency Syndrome Patient. Infection & Chemotherapy, 50, 51-54.
https://doi.org/10.3947/ic.2018.50.1.51
[29]  Chang, D.K., Yoo, D.H., Kim, T.H., Kim, I.S., Jun, K.Y., Park, M.H. and Kim, S.Y. (1999) Burkitt’s Lymphoma Presenting as Ileocaecal Intussusception in Systemic Lupus Erythematosus. Clinical Rheumatology, 18, 253-256.
https://doi.org/10.1007/s100670050095
[30]  El Hage Chehade, H.H., Abtar, H.K. and Seblini, M.I. (2013) Simultaneous Double Ileoileal Intussusception Due to Burkitt’s Lymphoma in a Young Male. Journal of Surgical Case Reports, 2013, rjt031.
https://doi.org/10.1093/jscr/rjt031
[31]  Fernandes, C., Pinho, R., Ribeiro, I., Silva, J., Ponte, A., Leite, S. and Fraga, J. (2015) Recurrent Cecocolic Intussusception in a Young Woman. Gastroenterology & Hepatology, 38, 586-588.
https://doi.org/10.1016/j.gastrohep.2014.10.006
[32]  Fiordaliso, M., Panaccio, P., Costantini, R. and De Marco, A.F. (2021) Comparison between Children and Adults Intussusception. Description of Two Cases and Review of Literature. Annali Italiani di Chirurgia, 92, 268-276.
[33]  Márquez-Ustariz, A.C., Singh-Boscan, C.S. and Pinto-Lesmes, E. (2022) Intususcepción intestinal por linfoma de Burkitt en un paciente adulto. Primer reporte en Latinoamérica. Cirugía y Cirujanos, 90, 693-696.
https://doi.org/10.24875/CIRU.21000501
[34]  Özant, A., Arslan, K., Özçay, N. and Besim, H. (2018) Adult Multicentric Burkitt Lymphoma with Bowel Obstruction Due to Intussusception. Turkish Journal of Gastroenterology, 29, 361-364.
https://doi.org/10.5152/tjg.2018.17743
[35]  Sharma, P., Balasingham, S., Stawiarski, K., Rahmani, M., Costantino, A., Sharma, P., Xu, M. and Masoud, A. (2017) Burkitt Lymphoma as a Lead Point for Jejunojejunal Intussusception in a Human Immunodeficiency Virus Patient. Clinical Journal of Gastroenterology, 10, 342-350.
https://doi.org/10.1007/s12328-017-0747-y
[36]  Simson, R., Planner, A. and Alexander, R. (2017) Adult Burkitt’s Lymphoma Presenting as Intussusception: First UK Case Report. The Annals of The Royal College of Surgeons of England, 99, e206-e208.
https://doi.org/10.1308/rcsann.2017.0105
[37]  Wetter, A., Schaudt, A., Lehnert, T., Schmidt-Matthiesen, A., Jacobi, V. and Vogl, T.J. (2006) Small-Bowel Intussusception as a Rare Differential Diagnosis in HIV-Po-sitive Patients with Acute Abdominal Pain. European Radiology, 16, 952-953.
https://doi.org/10.1007/s00330-005-2785-y
[38]  Zerwas, E., Kemper-Martin, A. and Comes, A. (2008) A Case Report of Adult Colonic Intussusception. The Journal of the Louisiana State Medical Society, 160, 102-103, 105.
[39]  Felix, E.L., Cohen, M.H., Bernstein, A.D. and Schwartz, J.H. (1976) Adult Intussusception; Case Report of Recurrent Intussusception and Review of the Literature. The American Journal of Surgery, 131, 758-761.
https://doi.org/10.1016/0002-9610(76)90196-3
[40]  Neymark, M., Abramov, R., Dronov, M. and Gilshtein, H. (2021) Management of Adult Intussusception—A Case Series Experience from a Tertiary Center. World Journal of Surgery, 45, 3584-3591.
https://doi.org/10.1007/s00268-021-06277-z
[41]  Roschewski, M., Dunleavy, K., Abramson, J.S., Powell, B.L., Link, B.K., Patel, P., Bierman, P.J., Jagadeesh, D., Mitsuyasu, R.T., Peace, D., et al. (2020) Multicenter Study of Risk-Adapted Therapy with Dose-Adjusted EPOCH-R in Adults with Untreated Burkitt Lymphoma. Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology, 38, 2519-2529.
https://doi.org/10.1200/JCO.20.00303
[42]  Magrath, I., Adde, M., Shad, A., Venzon, D., Seibel, N., Gootenberg, J., Neely, J., Arndt, C., Nieder, M., Jaffe, E., et al. (1996) Adults and Children with Small Non-Cleaved-Cell Lymphoma Have a Similar Excellent Outcome When Treated with the Same Chemotherapy Regimen. Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology, 14, 925-934.
https://doi.org/10.1200/JCO.1996.14.3.925
[43]  Barnes, J.A., Lacasce, A.S., Feng, Y., Toomey, C.E., Neuberg, D., Michaelson, J.S., Hochberg, E.P. and Abramson, J.S. (2011) Evaluation of the Addition of Rituximab to CODOX-M/IVAC for Burkitt’s Lymphoma: A Retrospective Analysis. Annals of Oncology, 22, 1859-1864.
https://doi.org/10.1093/annonc/mdq677
[44]  Samra, B., Khoury, J.D., Morita, K., Ravandi, F., Richard-Carpentier, G., Short, N.J., El Hussein, S., Thompson, P., Jain, N., Kantarjian, H., et al. (2021) Long-Term Outcome of Hyper-CVAD-R for Burkitt Leukemia/Lymphoma and High-Grade B-Cell Lymphoma: Focus on CNS Relapse. Blood Advances, 5, 3913-3918.
https://doi.org/10.1182/bloodadvances.2021004427
[45]  Chamuleau, M. (2022) R-CODOX-M/R-IVAC versus Dose-Adjusted (DA)-EPO-CH-R in Patients with Newly Diagnosed High-Risk Burkitt Lymphoma; First Results of a Multi-Center Randomized Hovon/Sakk Trial [Abstract LB2370]. Proceedings of the European Hematology Association Congress EHA2022, Vienna, 9-12 June 2022.
[46]  Sykorová, A., Procházka, V., Móciková, H., Janíková, A., Pytlík, R., Belada, D., Benešová, K., Klener, P., Ďuraš, J., Smolej, L., et al. (2022) Burkitt Lymphoma—A Retrospective Analysis of Data from the Registry of the Czech Lymphoma Study Group with External Validation of the Burkitt Lymphoma International Prognostic Index. Neoplasma, 69, 1466-1473.
https://doi.org/10.4149/neo_2022_221030N1064

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