Purpose: Insufficient epidemiological data on the prevalence
of chromosomal abnormalities may hamper
investments in research and interventions for better prevention and
treatment of these major threats to the population in numerous countries. The
aim of this literature review is to contribute to the popularization of
cytogenetics. Methodology: This literature review is a text which contains, analyzes and organizes several referenced
articles in French and English which have been selected from electronic
databases. It provides a documentation of
various activities and progress that have an interest in the field of
cytogenetics. Results: In the context of cytogenetics, it is necessary
to establish partnerships to strengthen infrastructures and produce quality
results. The setting up of cytogenetic services and incentives for participatory
research give space to the community in the
production of knowledge and innovation,
alongside researchers. It’s important to create biobanks, where samples
of substances from the human body are collected for use in research into the
causes and mechanisms of many diseases and their treatments. To carry out clinical trials aims at assessing the
effectiveness of a therapeutic strategy, as is currently the case with
the use of cytogenetic tests (karyotype, FISH, etc.) as tool of therapeutic
decision and prognostic in cancer biology. The monitoring of the ethic of
cytogenetic research projects allows protecting rights, security and welfare of
subjects. To solve issues of data management and analysis such as the obstacle
to the acquisition of tools and the insufficiency in the training of
researchers. Furthermore, dissemination of research results will lead to better understanding of research results, greater
public engagement in science and greater social respect for research. Conclusion:
Cytogenetics can benefit from these actions such as the development of its
research infrastructures and training programs for its workforce as well as the
development of its clinical care. All this would have an impact on the
population’s state of health.
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