Objectives:To determine the correlation between dermatosis papulosa nigra (DPN) and
cardiovascular disease (CVD). Patients and Method: A retrospective study
was conducted between April 2022 and March 2023 in cardiology at Loandjili
General Hospital. Were included all adult patients older than 18 years of age
presenting with DPN, and divided into two groups according to the presence of
CVD. Hypertension (HT), endomyocardial fibrosis, dilated and restrictive
cardiomyopathy, chronic pulmonary heart, ischemic heart disease, stroke, and
valvular heart disease were retained as CVD. Pregnant women, Peutz Jeghers
syndrome and all dermatosis with cardiovascular manifestations were excluded.
Studied variables were clinico-demographic, hereditary and behavioral. Results: A total of 55 patients were selected. There were 40 patients with CVD, 15
patients without CVD, 43 women (78.1%) and 12 men (21.8%). Mean age was 52 ± 12.6
years (extremes: 22-85 years). There was a
significant difference between age and sex (P < 0.05). There were 34 hypertensive patients, 10 patients with diabetes
mellitus, 7 strokes, 2 endomyocardial fibrosis and 2 ischemic heart diseases.
Periorbital location was representative was frequently found in the group with
CVD. Hereditary and behavioral factors were involved in the development of DPN
and CVD. There was a significant correlation between DPN and onset in childhood
(P<0.05), between
hypertension and use of medication (P<0.05),
and between onset in childhood (P<0.05)
and use of mercury containing soap (P
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