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脓毒症并发ARDS的研究进展
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Abstract:
脓毒症(sepsis)是宿主对感染反应失调引起的危及生命的器官功能障碍，是临床常见的危重症，具有很高的死亡率。急性呼吸窘迫综合征(ARDS)是急性肺部炎症性损伤疾病，是脓毒症发生发展过程中最常见、最严重的并发症之一，可引起脓毒症患者的病死率显著增加。目前治疗策略以器官功能支持为主，病死率仍居高不下，如今提倡对脓毒症相关ARDS患者实行精准的个体化治疗，随着各种新型生物标准物的发现，新型更精准化的治疗手段，为改善患者预后带来希望。本文对目前脓毒症相关ARDS的研究进展予以介绍。
Sepsis is a life-threatening organ dysfunction caused by the dysfunctional response of the host to infection, and is a common critical illness in clinical practice with a high mortality rate. Acute res-piratory distress syndrome (ARDS) is an acute inflammatory injury to the lungs, which is one of the most common and serious complications in the development of sepsis, which can lead to a signifi-cant increase in the mortality rate of patients with sepsis. At present, the treatment strategy is mainly based on organ function support, and the case fatality rate remains high, and now the pre-cise and individualized treatment of patients with sepsis-related ARDS is advocated, and with the discovery of various new biological standards, new and more precise treatment methods bring hope for improving the prognosis of patients. This article introduces the current research progress of sepsis-related ARDS.
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