皮肤Merkel细胞癌放射治疗1例
A Case of Merkel Cell Carcinoma of the Skin Treated with Radiotherapy

目的：探讨Merkel细胞癌镜下特点、临床表现、诊断和鉴别诊断、治疗方案、影响预后的因素。方法：对收治的1例Merkel细胞癌临床表现、治疗方案进行分析，并复习相关文献。结果：本病例考虑患者高龄，手术创伤较大，风险较高，选择放射治疗，该患者避免了术后疼痛，未发生并发症。结论：Merkel细胞癌是一种高度恶性的皮肤原发性神经内分泌癌，预后较差，对于可疑患者应尽早明确诊断并积极治疗，具体治疗方案依患者自身情况及病情而定。
Objective: To investigate the microscopic features, clinical manifestations, diagnosis and differential diagnosis, treatment options, and factors affecting prognosis of Merkel cell carcinoma. Methods: The clinical manifestations and treatment options of one case of Merkel cell carcinoma admitted were analyzed, and the relevant literature was reviewed. Results: In this case, considering the advanced age of the patient, the surgery was more traumatic and risky, radiation therapy was chosen, and this patient avoided postoperative pain without complications. Conclusion: Merkel cell carcinoma is a highly malignant primary neuroendocrine carcinoma of the skin with a poor prognosis, and suspicious patients should be clearly diagnosed and actively treated as early as possible, and the specific treatment plan depends on the patient’s own situation and condition.