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冠状动脉瘤样扩张研究进展
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Abstract:
冠状动脉瘤样扩张是冠状动脉的异常扩张，在临床上不常见，但也并不罕见的一种心血管疾病，其发生率为0.3%~5.3%。目前缺乏冠状动脉瘤样扩张患者的随机试验或大规模流行病学调查数据，因此针对这些患者的管理，使心脏病专家及临床医生面临相当大的挑战。很多情况下，冠状动脉瘤样扩张是行冠脉造影术患者中偶然发现的，并且发病机制仍有争议。治疗方法包括外科手术、经皮冠状动脉介入治疗和药物治疗。本文主要集中描述冠状动脉瘤样扩张的病因、发病机制、病理生理、诊断以及治疗等方面的临床特点，为进一步管理提供临床依据。
Coronary artery aneurysms is an abnormal dilation of the coronary artery and is a cardiovascular disease that is not common but also not rare, with an incidence rate of 0.3%~5.3%. Currently, there is a lack of randomized trials or large-scale epidemiological surveys on patients with coronary ar-tery ectasia, so the management of these patients poses a significant challenge for cardiologists and clinicians. In many cases, coronary artery aneurysm is incidentally discovered during coronary an-giography, and the pathogenesis is still controversial. Treatment options include surgical operation, percutaneous coronary intervention, and medical therapy. This article mainly focuses on the clinical characteristics of coronary artery aneurysm in terms of etiology, pathogenesis, pathophysiology, diagnosis, and treatment, providing clinical evidence for further management.
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