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酷似急性冠脉综合征的嗜酸性粒细胞性心肌炎一例
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Abstract:
特发性嗜酸性粒细胞增多症(idiopathic hypereosinophilic syndrome, IHES)是一种罕见的疾病，以持续性嗜酸性粒细胞增多为特征，表现为多个器官受累。这种疾病病因不明，且预后不良。嗜酸性粒细胞性心肌炎(eosinophilic myocarditis, EM)是IHES的主要并发症之一，患者的临床表现多种多样，轻者可无明显症状，重者可表现为急性暴发性心肌炎。心内膜心肌活检是EM诊断的金标准，心脏核磁共振(cardiac magnetic resonance, CMR)可作为辅助诊断。本文对陕西省人民医院收治的一例临床表现酷似急性冠脉综合征的EM患者进行报道。因本患者属罕见病例，其诊治过程可能不具有普适性，针对不同个体时应制定个性化治疗方案。此外，本文并未深入探讨EM的病因及发病机制，期待进一步的相关研究报道。
Idiopathic eosinophilia syndrome (IHES) is a rare disease characterized by persistent eosinophilia and multiple organ involvement. The etiology of this disease is unknown and the prognosis is poor. Eosinophilic myocarditis (EM) is one of the main complications of IHES. The clinical manifestations of patients are diverse, ranging from mild to asymptomatic to severe acute fulminant myocarditis. Endomyocardial biopsy is the gold standard for EM diagnosis, and cardiac magnetic resonance (CMR) can be used as an auxiliary diagnosis. This article reports a case of EM patient with clinical manifes-tations resembling acute coronary syndrome admitted to Shaanxi Provincial People’s Hospital. As this patient is a rare case, the diagnosis and treatment process may not be universal, and personal-ized treatment plans should be developed for different individuals. In addition, this article did not delve into the etiology and pathogenesis of EM, and further relevant research reports are expected.
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