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多模态功能磁共振成像在无先兆偏头痛中的研究进展
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Abstract:
偏头痛是一种原发性头痛，常伴随着头痛、恶心、呕吐等不适症状。无先兆偏头痛(migraine without aura, MwoA)占所有偏头痛类型的60%~80%，该病的发病机制至今尚未完全了解，但多模态功能磁共振技术相继完善并结合，为研究该病的病理机制和发生机制提供了有力的手段。本篇综述将从多模态功能磁共振研究的角度出发，全面、系统地探讨无先兆偏头痛的研究进展。
Migraine is a primary headache, often accompanied by headaches, nausea, vomiting and other dis-comfort symptoms. Migraine without aura (MwoA) accounts for 60% to 80% of all types of migraine, but the mechanism of the disease has not been fully understood, but multi-modular functional magnetic resonance technology is successively improved and combined, providing a powerful tool for the study of the pathological mechanisms and the occurrence of the condition. From the per-spective of multimodal functional magnetic resonance research, this review will comprehensively and systematically explore the progress of research on unprecedented migraines.
| [1] | 中国医师协会神经内科医师分会, 中国研究型医院学会头痛与感觉障碍专业委员会. 中国偏头痛诊治指南(2022版) [J]. 中国疼痛医学杂志, 2022, 28(12): 881-898. |
| [2] | Ashburner, J. and Friston, K.J. (2000) Voxel-Based Mor-phometry—The Methods. Neuroimage, 11, 805-821.
https://doi.org/10.1006/nimg.2000.0582 |
| [3] | Li, Z., et al. (2020) Concurrent Brain Structural and Functional Alter-ations in Patients with Migraine without Aura: An fMRI Study. The Journal of Headache and Pain, 21, Article No. 141. https://doi.org/10.1186/s10194-020-01203-5 |
| [4] | Qin, Z., et al. (2019) Structural Changes of Cerebellum and Brainstem in Migraine without Aura. The Journal of Headache and Pain, 20, Article No. 93. https://doi.org/10.1186/s10194-019-1045-5 |
| [5] | Yang, E., Nucifora, P.G. and Melhem, E.R. (2011) Diffusion MR Imaging: Basic Principles. Neuroimaging Clinics of North America, 21, 1-25. https://doi.org/10.1016/j.nic.2011.02.001 |
| [6] | 陈雪. 无先兆偏头痛患者脑结构和功能变化多模态磁共振研究[D]: [硕士学位论文]. 大连: 大连医科大学, 2021. |
| [7] | DaSilva, A.F., et al. (2007) Interictal Alterations of the Tri-geminal Somatosensory Pathway and Periaqueductal Gray Matter in Migraine. NeuroReport, 18, 301-305. https://doi.org/10.1097/WNR.0b013e32801776bb |
| [8] | Porcaro, C., et al. (2021) Hypothalamic Structural Integrity and Temporal Complexity of Cortical Information Processing at Rest in Migraine without Aura Patients between Attacks. Scientific Reports, 11, Article No. 18701.
https://doi.org/10.1038/s41598-021-98213-3 |
| [9] | Logothetis, N.K. (2008) What We Can Do and What We Cannot Do with fMRI. Nature, 453, 869-878.
https://doi.org/10.1038/nature06976 |
| [10] | Cucchiara, B., Datta, R., Aguirre, G.K., Idoko, K.E. and Detre, J. (2015) Measurement of Visual Sensitivity in Migraine: Validation of Two Scales and Correlation with Visual Cortex Activation. Cephalalgia, 35, 585-592.
https://doi.org/10.1177/0333102414547782 |
| [11] | Qin, Z., et al. (2020) Disrupted Functional Connectivity between Sub-Regions in the Sensorimotor Areas and Cortex in Migraine without Aura. The Journal of Headache and Pain, 21, Article No. 47.
https://doi.org/10.1186/s10194-020-01118-1 |
| [12] | Zhang, L.P., Huang, J.W., Zhang, Z.X. and Cao, Z.J. (2021) Al-tered Metabolites in the Occipital Lobe in Migraine without Aura during the Attack and the Interictal Period. Frontiers in Neurology, 12, Article 656349.
https://doi.org/10.3389/fneur.2021.656349 |
| [13] | Reyngoudt, H., et al. (2010) 1H-MRS of Brain Metabolites in Mi-graine without Aura: Absolute Quantification Using the Phantom Replacement Technique. Magnetic Resonance Materi-als in Physics, Biology and Medicine, 23, 227-241.
https://doi.org/10.1007/s10334-010-0221-z |
| [14] | Reyngoudt, H., Paemeleire, K., Descamps, B., De Deene, Y. and Achten, E. (2011) 31P-MRS Demonstrates a Reduction in High-Energy Phosphates in the Occipital Lobe of Migraine without Aura Patients. Cephalalgia, 31, 1243-1253.
https://doi.org/10.1177/0333102410394675 |
| [15] | Carroll, T.J. and Ginat, D.T. (2019) Using Dynamic Con-trast-Enhanced MRI as an Imaging Biomarker for Migraine: Proceed with Caution. Radiology, 292, 721-722. https://doi.org/10.1148/radiol.2019191159 |
| [16] | Giani, L., et al. (2019) Cerebral Blood Flow in Migraine without Aura: ASL-MRI Case Control Study. Neurological Sciences, 40, 183-184. https://doi.org/10.1007/s10072-019-03806-6 |
| [17] | 叶永强, 张军, 唐杰, 等. 磁共振动脉自旋标记法在无先兆偏头痛患者头痛发作期脑血流灌注中的应用[J]. 中华神经科杂志, 2017, 50(1): 40-43. |
