全部 标题 作者
关键词 摘要

OALib Journal期刊
ISSN: 2333-9721
费用:99美元

查看量下载量

相关文章

更多...

Testicular Burkitt’s Lymphoma: A Case Report and Literature Review

DOI: 10.4236/oju.2023.139037, PP. 327-336

Keywords: Burkitt’s Lymphoma, Orchidectomy, Testis

Full-Text   Cite this paper   Add to My Lib

Abstract:

Background: Burkitt’s lymphoma of the testis (TBL) is a rare and extremely aggressive malignant usually diagnosed in front of a testicular mass. We describe an interesting single case of TBL managed by a combined multimodal approach with a review of the literature. Case Report: A patient aged 69-year-old male, newly hypertensive, who presented with a twelve-month history of right testis progressive painful scrotal swelling, which worsens following a motorbike accident. Clinical examination revealed a large tender mass in an erythematous right scrotal bursa. A scrotal ultrasound showed a right heterogenous intra-testicular mass. The patient underwent unilateral (right) radical orchiectomy. Histopathological examination revealed presence of monomorphic lymphoid cells, with moderate to increased size, dissociated inconstantly by macrophages consistent with a Burkitt’s-like non-Hodgkin Lymphoma. After surgery, the patient was transferred to oncologist for adjuvant chemotherapy. Conclusion: A testicular mass is a usual circumstance for the discovery of a primary tumour of the testicle. Burkitt’s testicular lymphoma is a rare tumour whose diagnosis is based on histological findings. There are non-consensual etiological or predisposing factors. The treatment depends imperatively on the stage of the disease. Therapeutic modalities relay on in surgical excision, chemotherapy and radiation therapy but the accurate procedures are not standardized.

References

[1]  Crocetti, E., Capocaccia, R., Casella, C., Ferretti, S., Guzzinati, S., Rosso, S., Sacchettini, C., et al. (2004) Cancer Trends in Italy: Figures from the Cancer Registries (1986-1997). Epidemiologia & Prevenzione, 28, 1-6.
[2]  Satishchandra, H., Sridhar, A.S. and Pooja, B.P. (2013) Imaging of Burkitt’s Lymphoma-Abdominal Manifestations. Journal of Cancer Research and Therapeutics, 9, 128-130.
https://doi.org/10.4103/0973-1482.110383
[3]  Ogwang, M.D., Bhatia, K., Biggar, R.J. and Mbulaiteye, S.M. (2008) Incidence and Geographic Distribution of Endemic Burkitt Lymphoma in Northern Uganda Revisited. International Journal of Cancer, 123, 2658-2663.
https://doi.org/10.1002/ijc.23800
[4]  Vural, F., Cagirgan, S., Saydam, G., Hekimgil, M., Soyer, N.A. and Tombuloglu, M. (2007) Primary Testicular Lymphoma. Journal of the National Medical Association, 99, 1277-1282.
[5]  Linassier, C., Desablens, B., Lefrancq, T., Le Prise, P.Y., Harousseau, J.L., et al. (2002) Stage I-IIE Primary Non-Hodgkin’s Lymphoma of the Testis: Results of a Prospective Trial by the GOELAMS Study Group. Clinical Lymphoma, 3, 167-172.
https://doi.org/10.3816/CLM.2002.n.023
[6]  Ferry, J.A. (1994) Malignant Lymphoma of the Testis and Spermatic Cord. The American Journal of Surgical Pathology, 18, 376-390.
https://doi.org/10.1097/00000478-199404000-00006
[7]  Wirth, A. and Cheah, C.Y. (2017) Primary Testicular Lymphoma. In: Dabaja, B.S. and Ng, A.K., Eds., Radiation Therapy in Hematologic Malignancies: An Illustrated Practical Guide, Springer, Berlin, 129-141.
https://doi.org/10.1007/978-3-319-42615-0_9
[8]  Sow, M., Fouda, P.J., Nkegoum, B., EssameOyono, J.L., Garau, X.S. and Emo Malonga, E. (2011) Les Lymphomes primitifs urogénitaux: Expérience du service d’urologie de l’Hôpital Central de Yaoundé. Progrès en Urologie, 21, 198-202.
https://doi.org/10.1016/j.purol.2010.06.009
[9]  Frolund, U.C., Nielsen, S.L. and Hansen, P.B. (2011) Burkitt Lymphoma Is a Highly Malign Tumour with a Doubling Time of Twenty-Four Hours. Ugeskrift for Laeger, 173, 2714-2718. (In Danish)
[10]  Molyneux, E.M., Rochford, R., Griffin, B., et al. (2012) Burkitt’s Lymphoma. The Lancet, 379, 1234-1244.
https://doi.org/10.1016/S0140-6736(11)61177-X
[11]  Bouziani, A., M’sakni, I., Bougrine, F., Houissa, F. and Laabidi, B. (2004) Lymphomes malins non hodgkinien: Une cause rare de tumeur testiculaire.
[12]  Zicherman, J.M., Weissman, D., Gribbin, C. and Epstein, R. (2005) Best Cases from the AFIP: Primary Diffuse Large B-Cell Lymphoma of the Epididymis and Testis. RadioGraphics, 25, 243-248.
https://doi.org/10.1148/rg.251045041
[13]  Brouwer, C.L., Wiesendanger, E.M., van der Hulst, P.C., van Imhoff, G.W., Langendijk, J.A. and Beijert, M. (2013) Scrotal Irradiation in Primary Testicular Lymphoma: Review of the Literature and in Silico Planning Comparative Study. International Journal of Radiation Oncology, Biology, Physics, 85, 298-308.
https://doi.org/10.1016/j.ijrobp.2012.06.019
[14]  Lantz, A.G., Power, N., Hutton, B. and Gupta, R. (2009) Malignant Lymphoma of the Testis: A Study of 12 Cases. Canadian Urological Association Journal, 3, 393-398.
https://doi.org/10.5489/cuaj.1153
[15]  Verma, N., Chaudhary, U.B., Costa, L.J., Gudena, V. and Lazarchick, J. (2010) Primary Testicular Lymphoma and AIDS. Annals of Clinical & Laboratory Science, 40, 75-79.
[16]  Al-Abbadi, M.A., Hattab, E.M., Tarawneh, M.S., Amr, S.S., Orazi, A. and Ulbright, T.M. (2006) Primary Testicular Diffuse Large B-Cell Lymphoma Belongs to the Nongerminal Center B-Cell-Like Subgroup: A Study of 18 Cases. Modern Pathology, 19, 1521-1527.
https://doi.org/10.1038/modpathol.3800691
[17]  Chiappella, A. (2020) Testicular Lymphoma. Educational Updates in Hematology Book, 4, 1-2.
[18]  Srisuwan, T., Muttarak, M., Kitirattrakarn, P. and Ya-in, C. (2011) Clinics in Diagnostic Imaging (134). Testicular Lymphoma. Singapore Medical Journal, 52, 204-208.
[19]  Bhatia, K., Vaid, A.K., Gupta, S., Doval, D.C. and Talwar, V. (2007) Primary Testicular Non-Hodgkin’s Lymphoma—A Review Article. Sao Paulo Medical Journal, 125, 286-288.
https://doi.org/10.1590/S1516-31802007000500007
[20]  Wang, Q., Zheng, D.F., Chai, D.M., Wu, S.W., Wang, X.L., Chen, S.N., Wu, L.H., Cao, R.X. and Tao, Y.S. (2020) Primary Testicular Diffuse Large B-Cell Lymphoma: Case Series. Medicine, 99, e19463.
https://doi.org/10.1097/MD.0000000000019463
[21]  Hale, G.R., Teplitsky, S., Truong, H., et al. (2018) Lymph Node Imaging in Testicular Cancer. Translational Andrology and Urology, 7, 864-874.
https://doi.org/10.21037/tau.2018.07.18
[22]  Bart, J., Groen, H.J., van der Graaf, W.T., et al. (2002) An Oncological View on the Blood-Testis Barrier. The Lancet Oncology, 3, 357-363.
https://doi.org/10.1016/S1470-2045(02)00776-3
[23]  Sia, N.P.X., Chekrine, T., Bourhafour, M., Ouadii, K., Bouchbika, Z., Benchakroun, N., Jouhadi, H., Tawfiq, N., Benider, A., Marnissi, F., Madani, A., Karkouri, M. and Sahraoui, S. (2022) Primary Testicular Lymphoma: A Case Report and Review of the Literature. Journal of Cancer Therapy, 13, 145-154.
https://doi.org/10.4236/jct.2022.133011
[24]  Chen, B., Cao, D.H., Lai, L., et al. (2020) Adult Primary Testicular Lymphoma: Clinical Features and Survival in a Series of Patients Treated at a High-Volume Institution in China. BMC Cancer, 20, Article No. 220.
https://doi.org/10.1186/s12885-020-6711-0
[25]  Guner, S.I., Karacetin, D. and Yuksel, M. (2013) Primary Testicular Diffuse Large B-Cell Lymphoma: A Case Report. World Journal of Oncology, 4, 61-65.
https://doi.org/10.4021/wjon629w
[26]  Yahia, M., M’sakni, I., Laabidi, B., Gammoudi, A. and Bougrine, F. (2015) Primitive Burkitt Lymphoma in Testis Non-Endemic Area: A Report of a Case. Journal Africain du Cancer, 7, 240-243.

Full-Text

Contact Us

service@oalib.com

QQ:3279437679

WhatsApp +8615387084133