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慢性高原低氧对人体认知功能的影响
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Abstract:
目的：探索慢性3700米高原低氧暴露对人体认知功能的影响。方法：采用被试间实验设计，对慢性高原暴露2个月以上的工人与从未有过高原经历的平原工人的认知表现进行对比研究，共使用5项认知测试测量了3种认知功能，包括记忆、注意和执行功能。结果：高原组的短时记忆和抑制控制能力的反应时延长，工作记忆、选择性注意和注意集中的准确性下降，并且注意和执行功能的认知绩效表现也出现显著降低。结论：慢性高原低氧暴露对认人体认知功能的记忆、注意和执行功能均造成了部分损害。
Objective: To explore the effects of chronic 3700 m hypoxia exposure on human cognitive function. Methods: A comparative study was conducted using a between-subjects experimental design to examine the cognitive performance of workers with chronic plateau exposure for more than 2 months versus plain workers who had never experienced a plateau, using a total of 5 cognitive tests measuring 3 cognitive functions, including memory, attention, and executive function. Results: The plateau group had prolonged reaction times for short-term memory and inhibitory control, de-creased accuracy of working memory, selective attention, and attentional focus, and showed signifi-cantly lower cognitive performance in attention and executive functions. Conclusion: Chronic high altitudes hypoxia exposure partially impairs memory, attention, and executive functions in hu-mans.
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