In this research report, various Machine Learning (ML) models are discussed for the purpose of detecting brain anomalies like tumors. In the first step, we review previous work that uses Deep Learning (DL) to classify and detect brain tumors. Next, we present a detailed analysis of the ML methods in tabular form to address the brain tumor morphology, accessible datasets, segmentation, extraction, and classification using DL, and ML models. Finally, we summarize all relevant material for tumor detection, including the merits, limitations and future directions. In this study, it is found that employing DL-based and hybrid-based metaheuristic approaches proves to be more effective in accurately segmenting brain tumors, compared to the conventional methods. However, the brain tumor segmentation using ML models suffers from drawbacks due to limited labelled data, variability in tumor appearance, computational memory requirements, transparency in models, and difficulty in integration into clinical workflows. By pursuing techniques such as Data Augmentation, Pre-training, Active-learning, Multimodal fusion, Hardware acceleration, and Clinical integration, researchers and developers can overcome the bottlenecks and enhance the accuracy, efficiency, and clinical utility of ML-based brain tumor segmentation models.
References
[1]
Baid, U., et al. (2021) The RSNA-ASNR-MICCAI BraTS 2021 Benchmark on Brain Tumor Segmentation and Radiogenomic Classification. arXiv: 2107.02314.
[2]
Pereira, S., Pinto, A., Alves, V. and Silva, C.A. (2016) Brain Tumour Segmentation Using Convolutional Neural Networks in MRI Images. IEEE Transactions on Medical Imaging, 35, 1240-1251. https://doi.org/10.1109/TMI.2016.2538465
[3]
Alex, V., Safwan, M. and Krishnamurthy, G. (2017) Automatic Segmentation and Overall Survival Prediction in Gliomas Using Fully Convolutional Neural Network and Texture Analysis. In: Crimi, A., Bakas, S., Kuijf, H., Menze, B. and Reyes, M., Eds., Brainlesion: Glioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries, Springer, Cham, 216-225. https://doi.org/10.1007/978-3-319-75238-9_19
[4]
Abdelaziz Ismael, S.A., Mohammed, A. and Hefny, H. (2020) An Enhanced Deep Learning Approach for Brain Cancer MRI Images Classification Using Residual Networks. Artificial Intelligence in Medicine, 102, Article ID: 101779.
https://doi.org/10.1016/j.artmed.2019.101779
[5]
Amin, J., et al. (2020) Brain Tumor Detection by Using Stacked Autoencoders in Deep Learning. Journal of Medical Systems, 44, Article No. 32.
https://doi.org/10.1007/s10916-019-1483-2
[6]
Amin, J., Sharif, M., Gul, N., Yasmin, M. and Ali, S. (2020) Brain Tumor Classification Based on DWT Fusion of MRI Sequences Using Convolutional Neural Network. Pattern Recognition Letters, 129, 115-122.
https://doi.org/10.1016/j.patrec.2019.11.016
[7]
Anilkumar, B. and Rajesh Kumar, P. (2020) Tumor Classification Using Block Wise Fine Tuning and Transfer Learning of Deep Neural Network and KNN Classifier on MR Brain Images. International Journal of Emerging Trends in Engineering Research, 8, 574-583. https://doi.org/10.30534/ijeter/2020/48822020
[8]
Begum, S.S. and Lakshmi, D.R. (2020) Combining Optimal Wavelet Statistical tExture and Recurrent Neural Network for Tumour Detection and Classification over MRI. Multimedia Tools and Applications, 79, 14009-14030.
https://doi.org/10.1007/s11042-020-08643-w
[9]
Bhanothu, Y., Kamalakannan, A. and Rajamanickam, G. (2020) Detection and Classification of Brain Tumor in MRI Images Using Deep Convolutional Network. 2020 6th International Conference on Advanced Computing and Communication Systems (ICACCS), Coimbatore, 6-7 March 2020, 248-252.
https://doi.org/10.1109/ICACCS48705.2020.9074375
[10]
Çinar, A. and Yildirim, M. (2020) Detection of Tumors on Brain MRI Images Using the Hybrid Convolutional Neural Network Architecture. Medical Hypotheses, 139, Article ID: 109684. https://doi.org/10.1016/j.mehy.2020.109684
[11]
Deepak, V.K. and Sarath, R. (2022) An Intelligent Brain Tumor Segmentation Using Improved Deep Learning Model Based on Cascade Regression Method. Multimedia Tools and Applications, 82, 20059-20078.
[12]
Ghassemi, N., Shoeibi, A. and Rouhani, M. (2020) Deep Neural Network with Generative Adversarial Networks Pre-Training for Brain Tumor Classification Based on MR Images. Biomedical Signal Processing and Control, 57, Article ID: 101678.
https://doi.org/10.1016/j.bspc.2019.101678
[13]
Gull, S., Akbar, S. and Safdar, K. (2021) An Interactive Deep Learning Approach for Brain Tumor Detection Through 3D-Magnetic Resonance Images. International Conference on Frontiers of Information Technology (FIT), Islamabad, 13-14 December 2021, 114-119. https://doi.org/10.1109/FIT53504.2021.00030
[14]
Han, C., et al. (2019) Combining Noise-to-Image and Image-to-Image GANs: Brain MR Image Augmentation for Tumor Detection. IEEE Access, 7, 156966-156977.
https://doi.org/10.1109/ACCESS.2019.2947606
[15]
Haq, E.U., Jianjun, H., Li, K., Haq, H.U. and Zhang, T. (2023) An MRI-Based Deep Learning Approach for Efficient Classification of Brain Tumors. Journal of Ambient Intelligence and Humanized Computing, 14, 6697-6718
https://doi.org/10.1007/s12652-021-03535-9
[16]
Islam, R., Imran, S., Ashikuzzaman, M. and Khan, M.M.A. (2020) Detection and Classification of Brain Tumor Based on Multilevel Segmentation with Convolutional Neural Network. Journal of Biomedical Science and Engineering, 13, 45-53.
https://doi.org/10.4236/jbise.2020.134004
[17]
Jun, W. and Liyuan, Z. (2022) Brain Tumor Classification Based on Attention Guided Deep Learning Model. International Journal of Computational Intelligence Systems, 15, Article No. 35. https://doi.org/10.1007/s44196-022-00090-9
[18]
Kalaiselvi, T., Padmapriya, S.T., Sriramakrishnan, P. and Somasundaram, K. (2020) Deriving Tumor Detection Models Using Convolutional Neural Networks from MRI of Human Brain Scans. International Journal of Information Technology, 12, 403-408.
https://doi.org/10.1007/s41870-020-00438-4
[19]
Lakshmi, M.J. and Rao, S.N. (2022) Brain Tumor Magnetic Resonance Image Classification: A Deep Learning Approach. Soft Computing, 26, 6245-6253.
https://doi.org/10.1007/s00500-022-07163-z
[20]
Megha, H.C. (2020) Evaluation of Brain Tumor MRI Imaging Test Detection and Classification. International Journal for Research in Applied Science & Engineering Technology, 8, 124-131. https://doi.org/10.22214/ijraset.2020.6019
[21]
Togaçar, M., Ergen, B. and Comert, Z. (2020) BrainMRNet: Brain Tumor Detection Using Magnetic Resonance Images with a Novel Convolutional Neural Network Model. Medical Hypotheses, 134, Article ID: 109531.
https://doi.org/10.1016/j.mehy.2019.109531
[22]
Ozyurt, F., Sert, E. and Avci, D. (2020) An Expert System for Brain Tumor Detection: Fuzzy C-Means with Super Resolution and Convolutional Neural Network with Extreme Learning Machine. Medical Hypotheses, 134, Article ID: 109433.
https://doi.org/10.1016/j.mehy.2019.109433
[23]
Raj, A., Anil, A., Deepa, P.L., Aravind Sarma, H. and Naveen Chandran, R. (2020) BrainNET: A Deep Learning Network for Brain Tumor Detection and Classification. In: Jayakumari, J., Karagiannidis, G., Ma, M. and Hossain, S., Eds., Advances in Communication Systems and Networks, Springer, Singapore, 577-589.
https://doi.org/10.1007/978-981-15-3992-3_49
[24]
Raja, P.M.S. and Viswasa, A. (2020) Brain Tumor Classification Using a Hybrid Deep Autoencoder with Bayesian Fuzzy Clustering-Based Segmentation Approach. Biocybernetics and Biomedical Engineering, 40, 440-453.
https://doi.org/10.1016/j.bbe.2020.01.006
[25]
Ramtekkar, P.K., Pandey, A. and Pawar, M.K. (2023) Innovative Brain Tumor Detection Using Optimized Deep Learning Techniques. International Journal of System Assurance Engineering and Management, 14, 459-473.
https://doi.org/10.1007/s13198-022-01819-7
[26]
Ranjbarzadeh, R., Kasgari, A.B., Ghoushchi, S.J., Anari, S., Naseri, M. and Bendechache, M. (2021) Brain Tumor Segmentation Based on Deep Learning and an Attention Mechanism Using MRI Multi-Modalities Brain Images. Scientific Reports, 11, Article No. 10930. https://doi.org/10.1038/s41598-021-90428-8
[27]
Sarhan, A.M. (2020) Brain Tumor Classification in Magnetic Resonance Images Using Deep Learning and Wavelet Transform. Journal of Biomedical Science and Engineering, 13, 102-112. https://doi.org/10.4236/jbise.2020.136010
[28]
Sharif, M.I., Li, J.P., Khan, M.A. and Saleem, M.A. (2020) Active Deep Neural Network Features Selection for Segmentation and Recognition of Brain Tumors usIng MRI Images. Pattern Recognition, 129, 181-189.
https://doi.org/10.1016/j.patrec.2019.11.019
[29]
Shirwaikar, R.D., Ramesh, K. and Hiremath, A. (2021) A Survey on Brain Tumor Detection Using Machine Learning. 2021 International Conference on Forensics, Analytics, Big Data, Security (FABS), Bengaluru, 21-22 December 2021, 1-6.
https://doi.org/10.1109/FABS52071.2021.9702583
[30]
Vimal Kurup, R., Sowmya, V. and Soman, K.P. (2020) Effect of Data Pre-Processing on Brain Tumor Classification Using Capsulenet. In: Gunjan, V., Garcia Diaz, V., Cardona, M., Solanki, V. and Sunitha, K., Eds., ICICCT 2019—System Reliability, Quality Control, Safety, Maintenance and Management, Springer, Singapore, 110-119.
https://doi.org/10.1007/978-981-13-8461-5_13
[31]
Verma, A. and Singh, V.P. (2022) Design, Analysis and Implementation of Efficient Deep Learning Frameworks for Brain Tumor Classification. Multimedia Tools and Applications, 81, 37541-37567. https://doi.org/10.1007/s11042-022-13545-0
[32]
Feng, X., Tustison, N. and Meyer, C. (2020) Brain Tumor Segmentation Using an Ensemble of 3D U-Nets and Overall Survival Prediction Using Radiomic Features. Frontiers in Computational Neuroscience, 14, Article 25.
https://doi.org/10.3389/fncom.2020.00025