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影响幽门螺杆菌根除效果的研究进展
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Abstract:
幽门螺杆菌(Helicobacter pylori, Hp)是一种微需氧的螺旋状革兰阴性杆菌，不仅能引起多种胃肠道疾病，还参与其他胃外疾病的发展。根除Hp可以减少细菌的传播，利于消化性溃疡的愈合，阻止胃癌的发展，并降低其他相关疾病发生的风险。但近年来，Hp根除有效率并未有明显提高，反而呈下降趋势。导致Hp根除失败的原因有很多，因此，本文就影响Hp根除效果的研究现状及进展作一综述。
Helicobacter pylori is a microaerobic, spiral-shaped, and gram-negative bacillus which can not only cause a variety of gastrointestinal diseases, but also participate in the development of other extra-gastric diseases. H. pylori eradication can reduce the spread of bacteria, facilitate the healing of peptic ulcers, prevent the development of gastric cancer, and reduce the risk of other related dis-eases. However, in recent years, the effective rate of H. pylori eradication has not increased signifi-cantly, but has shown a downward trend. There are many reasons for the failure of H. pylori eradi-cation. Therefore, this article summarizes the research status and progress that affect the effect of H. pylori eradication.
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