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急性胰腺炎相关血清学指标及CT影像评分预测AP严重程度的研究进展
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Abstract:
急性胰腺炎(AP)是临床常见的消化急症，绝大多数轻症AP病情较轻，多呈自限性，患者预后良好；而严重的AP病情复杂，发展很快，它所导致的全身炎症反应综合征，以及器官功能衰竭的预后极差，死亡率达20%~40%。目前现有的病情评判标准缺乏快速、简便、准确的方法。有大量的研究证实红细胞分布宽度(RDW)、C反应蛋白(CRP)和抵抗素等血清标志物以及CT严重指数(CTSI)、改良CT严重指数(MCTSI)等影像评分应用于AP患者重症度及预后的判断。本文将对相关血清学指标及CT影像评分作一综述。
Acute pancreatitis (AP) is a common clinical digestive emergency, and most mild APs are mild, mostly self-limited, and the prognosis of patients is good. Severe AP is complex and develops rapidly, and the prognosis of systemic inflammatory response syndrome and organ failure caused by it is extremely poor, with a mortality rate of 20%~40%. At present, the existing criteria for assessing the condition lack a fast, simple, and accurate method. A large number of studies have confirmed that serum markers such as red blood cell distribution width (RDW), C-reactive protein (CRP) and resistin, as well as imaging scores such as CT severity index (CTSI) and modified CT severity index (MCTSI), are used to judge the severity and prognosis of AP patients. This article will review the relevant serological indicators and CT image scores.
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