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肝硬化并发SBP的诊断研究进展
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Abstract:
自发性细菌性腹膜炎(SBP)是肝硬化患者常见并发症、疾病进展的重要诱因及死亡的主要原因。肝硬化患者并发SBP起病隐匿、临床诊断困难，且其发病率高、预后差、死亡率高。然而，早期识别、诊断SBP对SBP患者至关重要，能改善预后、降低死亡率。为此，回顾国内外SBP诊断标准，查阅相关文献，分析诊断性腹腔穿刺、腹水相关检查及指标(外观、PMN计数、LERS、标记物)、炎性标记物、病原体检测(细菌培养、腹水细菌DNA检测)、早期预测模型等在肝硬化并发SBP中的诊断价值。
Spontaneous bacterial peritonitis (SBP) is a common complication, an important cause of disease progression, and a major cause of death in patients with cirrhosis. Patients with SBP have an insid-ious onset and difficult clinical diagnosis, and their incidence is high, prognosis is poor, and mortal-ity is high. However, early recognition and diagnosis of SBP are essential for patients with SBP to improve outcomes and reduce mortality. To this end, this paper reviews the diagnostic criteria for SBP at home and abroad, consults relevant literature, and scores analysis of diagnostic peritoneal puncture, ascites-related tests and indicators (appearance, PMN count, LERS, markers), inflamma-tory markers, pathogen detection (bacterial culture, ascites bacterial DNA detection), early predic-tion model, etc. in the diagnosis of liver cirrhosis complicated by SBP.
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