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基于古今医案云平台探讨中药治疗慢性萎缩性胃炎用药规律研究
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Abstract:
目的：通过古今医案云平台挖掘中药治疗慢性萎缩性胃炎的组方用药规律，为慢性萎缩性胃炎的临床治疗提供建议。方法：检索古今医案云平台中治疗慢性萎缩性胃炎的病案，筛选出中医治疗有效的验案，提取数据并建立数据库，对中药进行药物频次分析、属性分析、聚类分析、关联分析以及复杂网络分析。结果：经筛选后共纳入处方164首，中药237味，总用药频次2355次，频次最高的药物是白芍、白术、谷芽、半夏、炙甘草、茯苓等；药性以温、平、微寒为主；药味以甘、苦、辛、酸为主；药物归经以脾、胃、肺、肝经为主。常用药对谷芽–麦芽、茯苓–白术、半夏–干姜等；聚类分析及复杂网络分析结果显示中药治疗慢性萎缩性胃炎的核心处方。结论：中药治疗慢性萎缩性胃炎应以健脾益气、活血解毒、舒肝和胃为核心，佐以行气、燥湿、消食等药物。
Objective: To explore the prescription and medication rules of traditional Chinese medicine in the treatment of chronic atrophic gastritis through the cloud platform of ancient and modern medical cases, and provide suggestions for the clinical treatment of chronic atrophic gastritis. Methods: We search the medical records of chronic atrophic gastritis in the ancient and modern medical record cloud platform, screen out the effective cases of traditional Chinese medicine treatment, extract data and establish a database, and carry out drug frequency analysis, attribute analysis, cluster analysis, association analysis and complex network analysis on traditional Chinese medicine. Results: After screening, 164 prescriptions were included, including 237 Chinese herbs, with a total frequency of 2355 times. The drugs with the highest frequency were Paeonia lactiflora, Atractylodes macrocephala, corn bud, Pinellia ternata, roasted licorice, Poria cocos, etc.; The drug properties are mainly warm, mild and slightly cold; The medicine taste is mainly sweet, bitter, spicy and sour; The main meridians of drugs are spleen, stomach, lung and liver. Common medicine pairs: grain sprout-malt, Tuckahoe-Atractylodes macrocephala, Pinellia ternata-ginger, etc.; The results of cluster and complex network analysis show that the core prescription of traditional Chinese medicine for treating chronic atrophic gastritis. Conclusion: The treatment of chronic atrophic gastritis with traditional Chinese medicine should focus on invigorating the spleen and replenishing qi, promoting blood circulation and detoxification, soothing the liver and stomach, and be sup-plemented with drugs such as promoting qi, drying dampness, and digesting food.
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