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玫瑰痤疮的治疗方法研究进展
Research Progress in the Treatment of Rosacea

DOI: 10.12677/ACM.2023.1361373, PP. 9816-9822

Keywords: 玫瑰痤疮,复发性炎症,治疗方法
Rosacea
, Recurrent Inflammation, Treatment Methods

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Abstract:

玫瑰痤疮(Rosecea)是一种常见累及面中部的慢性复发性炎症性疾病,目前,由于发病机制和病理生理学尚不完全清楚,并缺乏生物标记和确切的药物靶点,导致该病的治疗成为临床医生所面临的重要挑战之一。本文将针对目前国内外玫瑰痤疮的研究及治疗进展进行综述,为临床治疗玫瑰痤疮优化治疗方法提供参考。
Rosecea is a common chronic recurrent inflammatory disease affecting the midface. Currently, the treatment of rosecea has become one of the important challenges faced by clinicians due to the lack of fully understood pathogenesis and pathophysiology, and the lack of biomarkers and exact drug targets. This article will review the current research and treatment progress of rosette acne at home and abroad, and provide reference for clinical treatment of rosette acne optimization treat-ment methods.

References

[1]  Wollina, U. (2019) Is Rosacea a Systemic Disease? Clinics in Dermatology, 37, 629-635.
https://doi.org/10.1016/j.clindermatol.2019.07.032
[2]  Ahn, C.S. and Huang, W.W. (2018) Rosacea Pathogenesis. Dermatologic Clinics, 36, 81-86.
https://doi.org/10.1016/j.det.2017.11.001
[3]  Wollina, U. (2014) Recent Advances in the Understanding and Management of Rosacea. F1000 Medicine Reports, 6, 50.
https://doi.org/10.12703/P6-50
[4]  Berg, M. and Liden, S. (1989) An Epidemiological Study of Rosacea. Acta Dermato-Venereologica, 69, 419-423.
[5]  Parisi, R. and Yiu, Z.Z.N. (2018) The Worldwide Epidemiology of Rosacea. British Journal of Dermatology, 179, 239-240.
[6]  Wang, Y., Zhao, Z., Liu, F., et al. (2020) Relationship between the Incidence of Rosacea and Drinking or Smoking in China. Journal of Central South University. Medical Sciences, 45, 165-168.
[7]  Gallo, R.L., Granstein, R.D., Kang, S., Man-nis, M., Steinhoff, M., Tan, J. and Thiboutot, D. (2018) Standard Classification and Pathophysiology of Rosacea: The 2017 Update by the National Rosacea Society Expert Committee. Journal of the American Academy of Dermatology, 78, 148-155.
https://doi.org/10.1016/j.jaad.2017.08.037
[8]  Johnson, S.M., Berg, A. and Barr, C. (2020) Managing Rosacea in the Clinic: From Pathophysiology to Treatment—A Review of the Literature. The Journal of Clinical and Aesthetic Dermatology, 13, S17-S22.
[9]  Wilkin, J., Dahl, M., Detmar, M., et al. (2004) Standard Grading System for Rosacea: Report of the National Rosacea Society Expert Committee on the Classification and Staging of Rosacea. Journal of the American Academy of Dermatology, 50, 907-912.
https://doi.org/10.1016/j.jaad.2004.01.048
[10]  Rosso, J.D. (2012) Advances in Understanding and Managing Rosacea: Part 1: Connecting the Dots between Pathophysiological Mechanisms and Common Clinical Features of Rosacea with Emphasis on Vascular Changes and Facial Erythema. Journal of Clinical & Aesthetic Dermatology, 5, 16-25.
[11]  Two, A.M. and Del Rosso, J.Q. (2014) Kallikrein 5-Mediated Inflammation in Rosacea: Clinically Relevant Correlations with Acute and Chronic Manifestations in Rosacea and How Individual Treatments May Provide Therapeutic Benefit. Journal of Clinical & Aesthetic Dermatology, 7, 20-25.
[12]  潘廷猛, 陈雪路, 施雯, 荣光辉, 何彩凤. 羟氯喹联合多西环素序贯光电协同治疗I型及II型玫瑰痤疮临床观察[J]. 中国美容医学, 2020, 29(9): 22-26.
[13]  Schaller, M., Almeida, L., Bewley, A., et al. (2017) Rosacea Treatment Update: Recommendations from the Global ROSacea COnsensus (ROSCO) Panel. British Journal of Der-matology, 176, 465-471.
https://doi.org/10.1111/bjd.15173
[14]  Kim, J.H., Oh, Y.S. and Choi, E.H. (2011) Oral Azithromycin for Treat-ment of Intractable Rosacea. Journal of Korean Medical Science, 26, 694-696.
https://doi.org/10.3346/jkms.2011.26.5.694
[15]  Rezakovi?, S., Mokos, Z.B. and Pa?tar, Z. (2015) Pyridoxine In-duced Rosacea-Like Dermatitis. Acta Clinica Croatica, 54, 99-102.
[16]  Lee, G.L. and Zirwas, M.J. (2015) Granulom-atous Rosacea and Periorificial Dermatitis. Dermatologic Clinics, 33, 447-455.
https://doi.org/10.1016/j.det.2015.03.009
[17]  赵旭明, 温杰, 吴远慧, 等. 低剂量异维A酸治疗难治性丘疹脓疱型玫瑰痤疮的临床疗效[J]. 中国中西医结合皮肤性病学杂志, 2021, 20(6): 557-560.
[18]  徐晓静, 朱元杰. 不同剂量异维A酸联合脉冲染料激光治疗酒渣鼻的疗效及安全性分析[J]. 中国美容医学, 2021, 30(1): 73-76.
[19]  Wang, B., Yuan, X., Huang, X., et al. (2021) Efficacy and Safety of Hydroxychloroquine for Treatment of Patients with Rosacea: A Multicenter, Randomized, Double-Blind, Double-Dummy, Pilot Study. Journal of the American Academy of Dermatology, 84, 543-545.
https://doi.org/10.1016/j.jaad.2020.05.050
[20]  Schaller, M., Almeida, L.M., Bewley, A., Cribier, B., et al. (2017) Rosacea Treatment Update: Recommendations from the Global ROSacea COnsensus (ROSCO) Panel. British Journal of Dermatology, 176, 465-471.
https://doi.org/10.1111/bjd.15173
[21]  刘乐, 陈文慧. 羟氯喹联合盐酸多西环素治疗玫瑰痤疮疗效观察[J]. 中国中西医结合皮肤性病学杂志, 2020, 19(5): 431-432.
[22]  Guiguemde, W., Shelat, A., Garcia-Bustos, J., et al. (2012) Global Phenotypic Screening for Antimalarials. Chemistry & Biology, 19, 116-129.
https://doi.org/10.1016/j.chembiol.2012.01.004
[23]  Schaller, M., Almeida, L.M.C., Bewley, A., Cribier, B., et al. (2020) Recommendations for Rosacea Diagnosis, Classification and Management: Update from the Global Rosacea Consensus 2019 Panel. British Journal of Dermatology, 182, 1269-1276.
https://doi.org/10.1111/bjd.18420
[24]  Hsu, C.C. and Lee, J.Y. (2011) Carvedilol for the Treatment of Refractory Facial Flushing and Persistent Erythema of Rosacea. Archives of Dermatology, 147, 1258-1260.
https://doi.org/10.1001/archdermatol.2011.204
[25]  Pietschke, K. and Schaller, M. (2017) Long-Term Management of Distinct Facial Flushing and Persistent Erythema of Rosacea by Treatment with Carvedilol. Journal of Dermatological Treatment, 29, 310-313.
https://doi.org/10.1080/09546634.2017.1360991
[26]  Seo, B.H., Dong, H.K., Suh, H.S., et al. (2020) Facial Flushing and Erythema of Rosacea Improved by Carvedilol. Dermatologic Therapy, 33, e14520.
[27]  van Zuuren, E.J., Fedorowicz, Z., Tan, J., van der Linden, M.M.D., Arents, B.W.M., Carter, B. and Charland, L. (2019) Interventions for Rosacea Based on the Phenotype Approach: An Updated Systematic Review Including GRADE Assessments. British Journal of Dermatology, 181, 65-79.
https://doi.org/10.1111/bjd.17590
[28]  Coda, A.B., Hata, T., Miller, J., et al. (2013) Cathelicidin, Kallikrein 5, and Serine Protease Activity Is Inhibited during Treatment of Rosacea with Azelaic Ac-id 15% Gel. Journal of the American Academy of Dermatology, 69, 570-577.
https://doi.org/10.1016/j.jaad.2013.05.019
[29]  Nakagawa, H., Nemoto, O., Igarashi, A., Saeki, H., Kabashima, K., Oda, M. and Nagata, T. (2021) Delgocitinib Ointment in Pediatric Patients with Atopic Dermatitis: A Phase 3, Random-ized, Double-Blind, Vehicle-Controlled Study and a Subsequent Open-Label, Long-Term Study. Journal of the American Academy of Dermatology, 85, 854-862.
https://doi.org/10.1016/j.jaad.2021.06.014
[30]  Starosta, D.A. and Lorenz, B. (2021) Pediatric Ocular Rosacea Ef-fectively Treated with Topical 1.5% Azithromycin Eye Drops. Der Ophthalmologe, 118, 68-73.
https://doi.org/10.1007/s00347-020-01279-z
[31]  Husein-El Ahmed, H. and Steinhoff, M. (2020) Efficacy of Top-ical Ivermectin and Impact on Quality of Life in Patients with Papulopustular Rosacea: A Systematic Review and Me-ta-Analysis. Dermatologic Therapy, 33, e13203.
https://doi.org/10.1111/dth.13203
[32]  Trave, I., Merlo, G., Cozzani, E., et al. (2019) Real-Life Experience on Ef-fectiveness and Tolerability of Topical Ivermectin in Papulopustular Rosacea and Antiparasitic Effect on Demodex Mites. Dermatologic Therapy, 32, e13093.
https://doi.org/10.1111/dth.13093
[33]  Aronson, I.K., Rumsfield, J.A., West, D.P., et al. (1987) Evaluation of Topical Metronidazole Gel in Acne Rosacea. Drug Intelligence & Clinical Pharmacy, 21, 346-351.
https://doi.org/10.1177/106002808702100410
[34]  Nielsen, P.G. (1983) Treatment of Rosacea with 1% Metroni-dazole Cream. A Double-Blind Study. British Journal of Dermatology, 108, 327-332.
https://doi.org/10.1111/j.1365-2133.1983.tb03972.x
[35]  Maddin, S. (1999) A Comparison of Topical Azelaic Acid 20% Cream and Topical Metronidazole 0.75% Cream in the Treatment of Patients with Papulopustular Rosacea. Journal of the American Academy of Dermatology, 40, 961-965.
https://doi.org/10.1016/S0190-9622(99)70085-X
[36]  Elewski, B.E., Fleischer, A.B. and Pariser, D.M. (2019) A Comparison of 15% Azelaic Acid Gel and 0.75% Metronidazole Gel in the Topical Treatment of Papulopustular Rosacea Results of a Randomized Trial.
https://doi.org/10.1001/archderm.139.11.1444
[37]  Shemer, A., Shiri, J., Mashiah, J., et al. (2016) Topical Mino-cycline Foam for Moderate to Severe Acne Vulgaris: Phase 2 Randomized Double-Blind, Vehicle-Controlled Study Re-sults. Journal of the American Academy of Dermatology, 74, 1251-1252.
https://doi.org/10.1016/j.jaad.2015.09.065
[38]  Gold, L.S., Del Rosso, J.Q., Kircik, L., et al. (2020) Minocycline 1.5% Foam for the Topical Treatment of Moderate to Severe Papulopustular Rosacea: Results of 2 Phase 3, Randomized, Clinical Trials. Journal of the American Academy of Dermatology, 82, 1166-1173.
https://doi.org/10.1016/j.jaad.2020.01.043
[39]  Webster, G., Draelos, Z.D., Graber, E., et al. (2020) A Multicentre, Randomized, Double-Masked, Parallel Group, Vehicle-Controlled Phase IIb Study to Evaluate the Safety and Efficacy of 1% and 3% Topical Minocycline Gel in Patients with Papulopustular Rosacea. British Journal of Dermatology, 183, 471-479.
https://doi.org/10.1111/bjd.18857
[40]  Zuuren, E.J.V., Fedorowicz, Z., Tan, J., et al. (2019) Evi-dence-Based Treatments for Rosacea Based on Phenotype Approach. British Journal of Dermatology, 181, e16.
https://doi.org/10.1111/bjd.18064
[41]  Kim, B.Y., Moon, H.R. and Ryu, H.J. (2019) Comparative Efficacy of Short-Pulsed Intense Pulsed Light and Pulsed Dye Laser to Treat Rosacea. Journal of Cosmetic and Laser Therapy, 21, 291-296.
https://doi.org/10.1080/14764172.2018.1528371
[42]  Liu, J., Liu, J., Ren, Y., et al. (2014) Comparative Efficacy of Intense Pulsed Light for Different Erythema Associated with Rosacea. Journal of Cosmetic and Laser Therapy, 16, 324-327.
https://doi.org/10.3109/14764172.2014.957218
[43]  Zhang, Y., Jiang, S., Lu, Y., et al. (2020) A Decade Retrospective Study of Light/Laser Devices in Treating Nasal Rosacea. Journal of Dermatological Treatment, 31, 84-90.
https://doi.org/10.1080/09546634.2019.1580669
[44]  Friedmann, D.P., Goldman, M.P., Fabi, S.G., et al. (2018) Comparison of Efficacy between Long-Pulsed Nd:YAG Laser and Pulsed Dye Laser to Treat Rosacea-Associated Nasal Telangiectasia. Journal of Cosmetic and Laser Therapy, 20, 260-264.
https://doi.org/10.1080/14764172.2017.1418510
[45]  Lee, J.H., Na, S.Y., Choi, M., et al. (2012) Long-Pulsed Nd:YAG Laser: Does It Give Clinical Benefit on the Treatment of Resistant Telangiectasia? The Journal of the European Academy of Dermatology and Venereology, 26, 1280-1284.
https://doi.org/10.1111/j.1468-3083.2011.04282.x
[46]  中国医师协会皮肤科医师分会皮肤美容亚专业委员会. 中国玫瑰痤疮诊疗专家共识(2016) [J]. 中华皮肤科杂志, 2017, 50(3): 156-157.
[47]  赵梓刚, 李承新. 玫瑰痤疮的非药物治疗[J]. 皮肤病与性病, 2017, 40(2): 96-98.
[48]  Meesters, A.A., van der Linden, M.M. and De Rie, M.A. (2015) Fractionated Carbon Dioxide Laser Therapy as Treatment of Mild Rhinophyma: Report of Three Cases. Derma-tologic Therapy 28, 147-150.
https://doi.org/10.1111/dth.12205
[49]  Orenstein, A., Haik, J., Tamir, J., et al. (2001) Treatment of Rhinophyma with Er:YAG Laser. Lasers in Surgery and Medicine, 29, 230-235.
https://doi.org/10.1002/lsm.1112
[50]  Tanghetti, E.A., Goldberg, D.J., Dover, J.S., Geronemus, R.G., Bai, Z., Al-vandi, N. and Shanler, S.D. (2021) Oxymetazoline and Energy-Based Therapy in Patients with Rosacea: Evaluation of the Safety and Tolerability in an Open-Label, Interventional Study. Lasers in Surgery and Medicine, 53, 55-65.
https://doi.org/10.1002/lsm.23253
[51]  Suggs, A.K., Macri, A., Richmond, H., Munavalli, G. and Friedman, P.M. (2020) Treatment of Erythematotelangiectatic Rosacea with Pulsed-Dye Laser and Oxymetazoline 1.0% Cream: A Retro-spective Study. Lasers in Surgery and Medicine, 52, 38-43.
https://doi.org/10.1002/lsm.23176
[52]  方方, 张国成. 协和皮肤外科学[M]. 北京: 中国协和医科大学出版社, 2008: 124-125.

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