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临床常用检验、检查对颅脑损伤预后的研究现状
Current Research Status of Commonly Used Clinical Tests and Examinations on the Prognosis of Craniocerebral Injury

DOI: 10.12677/ACM.2023.1361278, PP. 9125-9132

Keywords: 颅脑损伤,血液检验,影像学,现状
Brain Injury
, Blood Test, Imaging, Present Situation

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Abstract:

血液检验以及影像学检查已经广泛应用于颅脑损伤,常用的血液检验及影像学检查往往能为颅脑损伤患者的诊断及治疗提供依据。选取血红蛋白、红细胞比容、中性粒细胞、中性粒细胞/淋巴细胞、淋巴细胞/单核细胞、血小板、血小板分布宽度等进行检测,CT、MRI进行检查。常用的血液检验及影像学检查对颅脑损伤病情变化、损伤程度、预后有关联的检查、检验项目分别进行综述,阐述其变化的临床意义。
Blood test and imaging examination have been widely used in craniocerebral injury. The commonly used blood test and imaging examination can often provide basis for the diagnosis and treatment of patients with craniocerebral injury. Hemoglobin, hematocrit, red blood cell distribution width, NLR, MLR, platelet, platelet distribution width, coagulation factor, etc. were selected for examination, and CT and MRI were used for examination. The commonly used blood tests and imaging examinations are reviewed for the examination and test items related to the changes in the condition, severity, and prognosis of brain injury, and the clinical significance of their changes is expounded.

References

[1]  Maas, A.I., Menon, D.K., Adelson, P.D., et al. (2017) Traumatic Brain Injury: Integrated Approaches to Improve Pre-vention, Clinical Care, and Research. The Lancet Neurology, 16, 987-1048.
https://doi.org/10.1016/S1474-4422(17)30371-X
[2]  Jiang, J.Y., Gao, G.Y., Feng, J.F., et al. (2019) Traumatic Brain Injury in China. The Lancet Neurology, 18, 286-295.
https://doi.org/10.1016/S1474-4422(18)30469-1
[3]  Hazeldine, J., Lord, J.M. and Belli, A. (2015) Traumatic Brain Injury and Peripheral Immune Suppression: Primer and Prospectus. Frontiers in Neurology, 6, Article 235.
https://doi.org/10.3389/fneur.2015.00235
[4]  Werner, C. and Engelhard, K. (2007) Pathophysiology of Traumatic Brain Injury. BJA: British Journal of Anaesthesia, 99, 4-9.
https://doi.org/10.1093/bja/aem131
[5]  Montenigro, P.H., Baugh, C.M., Daneshvar, D.H., et al. (2014) Clinical Subtypes of Chronic Traumatic Encephalopathy: Literature Review and Proposed Research Diagnostic Criteria for Traumatic Encephalopathy Syndrome. Alzheimer’s Research & Therapy, 6, Article No. 68.
https://doi.org/10.1186/s13195-014-0068-z
[6]  Kim, E., Lauterbach, E.C., Reeve, A., et al. (2007) Neuropsychiatric Complications of Traumatic Brain Injury: A Critical Review of the Literature (a Report by the ANPA Committee on Research). The Journal of Neuropsychiatry and Clinical Neurosciences, 19, 106-127.
https://doi.org/10.1176/jnp.2007.19.2.106
[7]  Hill, C.S., Coleman, M.P. and Menon, D.K. (2016) Traumatic Ax-onal Injury: Mechanisms and Translational Opportunities. Trends in Neurosciences, 39, 311-324.
https://doi.org/10.1016/j.tins.2016.03.002
[8]  Lafrenaye, A.D., Todani, M., Walker, S.A. and Povlishock, J.T. (2015) Microglia Processes Associate with Diffusely Injured Axons following Mild Traumatic Brain Injury in the Micro Pig. Journal of Neuroinflammation, 12, Article No. 186.
https://doi.org/10.1186/s12974-015-0405-6
[9]  Browne, K.D., Chen, X.H., Meaney, D.F. and Smith, D.H. (2011) Mild Traumatic Brain Injury and Diffuse Axonal Injury in Swine. Journal of Neurotrauma, 28, 1747-1755.
https://doi.org/10.1089/neu.2011.1913
[10]  Topal, N.B., Hakyemez, B., Erdogan, C., et al. (2008) MR Imaging in the Detection of Diffuse Axonal Injury with Mild Traumatic Brain Injury. Neurological Research, 30, 974-978.
https://doi.org/10.1179/016164108X323799
[11]  Greer, J.E., Povlishock, J.T. and Jacobs, K.M. (2012) Electrophysiological Abnormalities in Both Axotomized and Nonaxotomized Pyramidal Neurons following Mild Traumatic Brain Injury. Journal of Neuroscience, 32, 6682-6687.
https://doi.org/10.1523/JNEUROSCI.0881-12.2012
[12]  Greer, J.E., Mcginn, M.J. and Povlishock, J.T. (2011) Diffuse Traumatic Axonal Injury in the Mouse Induces Atrophy, c-Jun Activation, and Axonal Outgrowth in the Axoto-mized Neuronal Population. Journal of Neuroscience, 31, 5089-5105.
https://doi.org/10.1523/JNEUROSCI.5103-10.2011
[13]  Greer, J.E., H?nell, A., Mcginn, M.J. and Povlishock, J.T. (2013) Mild Traumatic Brain Injury in the Mouse Induces Axotomy Primarily within the Axon Initial Segment. Acta Neuropathologica, 126, 59-74.
https://doi.org/10.1007/s00401-013-1119-4
[14]  Nortje, J. and Menon, D.K. (2004) Traumatic Brain Injury: Physi-ology, Mechanisms, and Outcome. Current Opinion in Neurology, 17, 711-718.
https://doi.org/10.1097/00019052-200412000-00011
[15]  Baethmann, A., Eriskat, J., Stoffel, M., et al. (1998) Special Aspects of Severe Head Injury: Recent Developments. Current Opinion in Anesthesiology, 11, 193-200.
https://doi.org/10.1097/00001503-199804000-00013
[16]  Helmy, A., Carpenter, K.L., Menon, D.K., Pickard, J.D. and Hutchinson, P.J.A. (2011) The Cytokine Response to Human Traumatic Brain Injury: Temporal Profiles and Evi-dence for Cerebral Parenchymal Production. Journal of Cerebral Blood Flow & Metabolism, 31, 658-670.
https://doi.org/10.1038/jcbfm.2010.142
[17]  Valadka, A.B., Gopinath, S.P., Contant, C.F., et al. (1998) Relation-ship of Brain Tissue PO2 to Outcome after Severe Head Injury. Critical Care Medicine, 26, 1576-1581.
https://doi.org/10.1097/00003246-199809000-00029
[18]  Oddo, M., Levine, J.M., Kumar, M., et al. (2012) Ane-mia and Brain Oxygen after Severe Traumatic Brain Injury. Intensive Care Medicine, 38, 1497-1504.
https://doi.org/10.1007/s00134-012-2593-1
[19]  Abbott, N.J., Patabendige, A.A.K., Dolman, D.E.M., Yusof, S.R. and Begley, D.J. (2010) Structure and Function of the Blood—Brain Barrier. Neurobiology of Disease, 37, 13-25.
https://doi.org/10.1016/j.nbd.2009.07.030
[20]  Mccredie, V.A., Piva, S., Santos, M., et al. (2017) The Impact of Red Blood Cell Transfusion on Cerebral Tissue Oxygen Saturation in Severe Traumatic Brain Injury. Neurocritical Care, 26, 247-255.
https://doi.org/10.1007/s12028-016-0310-6
[21]  Ekelund, A., Reinstrup, P., Ryding, E., et al. (2002) Effects of Iso- and Hypervolemic Hemodilution on Regional Cerebral Blood Flow and Oxygen Delivery for Patients with Vaso-spasm after Aneurysmal Subarachnoid Hemorrhage. Acta Neurochirurgica, 144, 712-713.
[22]  Sekhon, M.S., Mclean, N., Henderson, W.R., Chittock, D.R. and Griesdale, D.E.G. (2012) Association of Hemoglobin Concentration and Mor-tality in Critically Ill Patients with Severe Traumatic Brain Injury. Critical Care, 16, Article No. R128.
https://doi.org/10.1186/cc11431
[23]  Marmarou, A., Signoretti, S., Fatouros, P.P., et al. (2006) Predominance of Cellular Edema in Traumatic Brain Swelling in Patients with Severe Head Injuries. Journal of Neurosurgery, 104, 720-730.
https://doi.org/10.3171/jns.2006.104.5.720
[24]  Nijboer, J.M., Van Der Horst, I.C.C., Hendriks, H.G., et al. (2007) Myth or Reality: Hematocrit and Hemoglobin Differ in Trauma. Journal of Trauma and Acute Care Surgery, 62, 1310-1312.
https://doi.org/10.1097/TA.0b013e3180341f54
[25]  Liu, Y.W., Li, S. and Dai, S.S. (2018) Neutrophils in Trau-matic Brain Injury (TBI): Friend or Foe? Journal of Neuroinflammation, 15, Article No. 146.
https://doi.org/10.1186/s12974-018-1173-x
[26]  Semple, B.D., Bye, N., Ziebell, J.M. and Morganti-Kossmann, M.C. (2010) Deficiency of the Chemokine Receptor CXCR2 Attenuates Neutrophil Infiltration and Cortical Damage fol-lowing Closed Head Injury. Neurobiology of Disease, 40, 394-403.
https://doi.org/10.1016/j.nbd.2010.06.015
[27]  Connolly, E., Winfree, C.J., Springer, T.A., et al. (1996) Cerebral Protection in Homozygous Null ICAM-1 Mice after Middle Cerebral Artery Occlusion. Role of Neutrophil Adhesion in the Pathogenesis of Stroke. The Journal of Clinical Investigation, 97, 209-216.
https://doi.org/10.1172/JCI118392
[28]  Matsuo, Y., Onodera, H., Shiga, Y., et al. (1994) Correlation between Myeloperoxidase-Quantified Neutrophil Accumulation and Ischemic Brain Injury in the Rat. Effects of Neutrophil Deple-tion. Stroke, 25, 1469-1475.
https://doi.org/10.1161/01.STR.25.7.1469
[29]  Carr, K.D., Sieve, A.N., Indramohan, M., et al. (2011) Specific Depletion Reveals a Novel Role for Neutrophil-Mediated Protection in the Liver during Listeria monocytogenes Infection. European Journal of Immunology, 41, 2666-2676.
https://doi.org/10.1002/eji.201041363
[30]  Navarini, A.A., Lang, K.S., Verschoor, A., et al. (2009) Innate Im-mune-Induced Depletion of Bone Marrow Neutrophils Aggravates Systemic Bacterial Infections. Proceedings of the Na-tional Academy of Sciences, 106, 7107-7112.
https://doi.org/10.1073/pnas.0901162106
[31]  Lewis, S.M., Khan, N., Beale, R., Treacher, D.F. and Brown, K.A. (2013) Depletion of Blood Neutrophils from Patients with Sepsis: Treatment for the Future? International Im-munopharmacology, 17, 1226-1232.
https://doi.org/10.1016/j.intimp.2013.10.002
[32]  Hazeldine, J., Hampson, P. and Lord, J.M. (2014) The Impact of Trauma on Neutrophil Function. Injury, 45, 1824-1833.
https://doi.org/10.1016/j.injury.2014.06.021
[33]  Adrian, H., M?rten, K., Salla, N., et al. (2016) Biomarkers of Traumatic Brain Injury: Temporal Changes in Body Fluids. eNeuro, 3, No. 6.
[34]  Engelborghs, S., Niemantsverdriet, E., Struyfs, H., et al. (2017) Consensus Guidelines for Lumbar Puncture in Patients with Neurological Diseases. Alz-heimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 8, 111-126.
https://doi.org/10.1016/j.dadm.2017.04.007
[35]  Headache Classification Committee of the International Headache Society (2016) The International Classification of Headache Disorders. Cephalalgia, 24, 1-160.
[36]  Donnelly, D.J. and Popovich, P.G. (2008) Inflammation and Its Role in Neuroprotection, Axonal Regeneration and Functional Recovery af-ter Spinal Cord Injury. Experimental Neurology, 209, 378-388.
https://doi.org/10.1016/j.expneurol.2007.06.009
[37]  Mantovani, A., Cassatella, M.A., Costantini, C. and Jaillon, S. (2011) Neutrophils in the Activation and Regulation of Innate and Adaptive Immunity. Nature Reviews Immunology, 11, 519-531.
https://doi.org/10.1038/nri3024
[38]  Morganti-Kossmann, M.C., Rancan, M., Stahel, P.F. and Kossmann, T. (2002) Inflammatory Response in Acute Traumatic Brain Injury: A Double-Edged Sword. Current Opinion in Critical Care, 8, 101-105.
https://doi.org/10.1097/00075198-200204000-00002
[39]  Liu, J., Li, S., Zhang, S., et al. (2019) Systemic Im-mune-Inflammation Index, Neutrophil-to-Lymphocyte Ratio, Platelet-to-Lymphocyte Ratio Can Predict Clinical Out-comes in Patients with Metastatic Non-Small-Cell Lung Cancer Treated with Nivolumab. Journal of Clinical Laboratory Analysis, 33, e22964.
https://doi.org/10.1002/jcla.22964
[40]  Stojkovic Lalosevic, M., Pavlovic Markovic, A., Stankovic, S., et al. (2019) Combined Diagnostic Efficacy of Neutrophil-to-Lymphocyte Ratio (NLR), Plate-let-to-Lymphocyte Ratio (PLR), and Mean Platelet Volume (MPV) as Biomarkers of Systemic Inflammation in the Di-agnosis of Colorectal Cancer. Disease Markers, 2019, Article ID: 6036979.
https://doi.org/10.1155/2019/6036979
[41]  Chen, T. and Yang, M. (2020) Platelet-to-Lymphocyte Ratio Is Associ-ated with Cardiovascular Disease in Continuous Ambulatory Peritoneal Dialysis Patients. International Immunophar-macology, 78, Article ID: 106063.
https://doi.org/10.1016/j.intimp.2019.106063
[42]  Owings, J.T., Bagley, M., Gosselin, R., Romac, D. and Disbrow, E. (1996) Effect of Critical Injury on Plasma antIthrombin Activity: Low Antithrombin Levels Are Associated with Thromboembolic Complications. Journal of Trauma and Acute Care Surgery, 41, 396-406.
https://doi.org/10.1097/00005373-199609000-00004
[43]  Andrews, R.K., López, J. and Berndt, M.C. (1997) Mo-lecular Mechanisms of Platelet Adhesion and Activation. The International Journal of Biochemistry & Cell Biology, 29, 91-105.
https://doi.org/10.1016/S1357-2725(96)00122-7
[44]  吴柏瑶, 吕立文, 唐宇涛, 等. 严重创伤患者大出血所致凝血功能障碍与预后的关系研究[J]. 中国全科医学, 2019(s1): 134-136.
[45]  付鹤鹏, 张玉想. 危重症患者血小板功能的评估及其临床意义[J]. 中华危重病急救医学, 2018, 30(3): 284-288.
[46]  王佳妮, 魏俊吉. 神经外科急诊合并凝血功能障碍的机制及治疗进展[J]. 中国医学科学院学报, 2013, 35(5): 576-580.
[47]  李民涛, 任光阳. 创伤性脑损伤后凝血功能异常机制的研究进展[J]. 医学综述, 2013, 19(8): 1365-1367.
[48]  李金亮. 中重度颅脑损伤后CT影像特点, 颅内压与预后的关系[J]. 中国当代医药, 2017, 24(25): 57-59.
[49]  Maas, A.I., Hukkelhoven, C.W., Marshall, L.F. and Steyerberg, E.W. (2005) Prediction of Outcome in Traumatic Brain Injury with Computed Tomographic Characteristics: A Comparison between the Computed Tomographic Classification and Combi-nations of Computed Tomographic Predictors. Neurosurgery, 57, 1173-1182.
https://doi.org/10.1227/01.NEU.0000186013.63046.6B
[50]  Teasdale, G., Galbraith, S., Murray, L., et al. (1982) Management of Traumatic Intracranial Haematoma. The BMJ, 285, Article 1695.
https://doi.org/10.1136/bmj.285.6356.1695
[51]  周丽景. 颅脑CT对急性脑外伤患者手术疗效及预后的评估价值分析[J]. 中国CT和MRI杂志, 2017, 15(3): 19-21.
[52]  Levin, H.S., Gary, H.E., Eisenberg, H.M. and Ronald, M.R. (1990) Neurobehavioral Outcome 1 Year after Severe Head Injury: Experience of the Traumatic Coma Data Bank. Journal of Neurosurgery, 73, 699-709.
https://doi.org/10.3171/jns.1990.73.5.0699
[53]  Ruff, R.M., Marshall, L., Crouch, J., et al. (1993) Predictors of Outcome following Severe Head Trauma: Follow-up Data from the Traumatic Coma Data Bank. Brain Injury, 7, 101-111.
https://doi.org/10.3109/02699059309008164
[54]  Mataró, M., Poca, M.A., Sahuquillo, J., et al. (2001) Neuro-psychological Outcome in Relation to the Traumatic Coma Data Bank Classification of Computed Tomography Imaging. Journal of Neurotrauma, 18, 869-879.
https://doi.org/10.1089/089771501750451794
[55]  Hammoud, D.A. and Wasserman, B.A. (2002) Diffuse Axonal Injuries: Pathophysiology and Imaging. Neuroimaging Clinics of North America, 12, 205-216.
https://doi.org/10.1016/S1052-5149(02)00011-4
[56]  Zimmerman, R.A., Bilaniuk, L.T., Hackney, D.B., et al. (1986) Head Injury: Early Results of Comparing CT and High-Field MR. American Journal of Neuroradiology, 7, 757-764.
[57]  Carney, N., Totten, A.M., O’reilly, C., et al. (2017) Guidelines for the Management of Severe Traumatic Brain Injury. Neurosurgery, 80, 6-15.
https://doi.org/10.1227/NEU.0000000000001432
[58]  李瑞琪, 王剑杰, 冯宝婕, 等. 磁共振成像在脑弥漫性轴索损伤中的诊断价值[J]. 中国CT和MRI杂志, 2008, 6(1): 10-12.

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