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跖疣的发病机制及治疗进展
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Abstract:
跖疣是一种角质形成细胞感染人乳头瘤病毒(Human papilloma virus, HPV)引起的足底表面病毒感染。它是足底的特殊的寻常疣，表现为圆形乳头状黄色或褐色角质增生，表面粗糙、干燥，周围绕以增厚的角质环，其下可见疏松的角质软芯，可见毛细血管破裂外渗凝固而形成的小黑点。可能引起疼痛、出血等不适。可发生于任何人群，尤以青年人多见。可通过直接或间接接触感染。疣具有自限性，但由于跖疣部位特殊，多被挤压摩擦，病变部位增厚，故不易清除。这篇综述就其发病机制及目前的治疗研究进展进行概述。
Plantar warts are a plantar surface infection caused by keratinocytes infected with the human pap-illoma virus (HPV). It is a special common warts on the soles of the foot, manifested as round papil-lary yellow or brown keratin, with a rough, dry surface, surrounded by a thickened cuticle ring, un-der which a loose keratin soft core can be seen, and small black spots formed by extravasation and coagulation of capillary rupture can be seen. It may cause discomfort such as pain and bleeding. It can occur in any population, especially young people. Infection can be achieved through direct or indirect contact. Warts are self-limited, but due to the special location of plantar warts, they are mostly squeezed and rubbed, and the lesions are thickened, so they are not easy to remove. This review provides an overview of its pathogenesis and current advances in treatment research.
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