全部 标题 作者
关键词 摘要

OALib Journal期刊
ISSN: 2333-9721
费用:99美元

查看量下载量

相关文章

更多...

Some Haematological Parameters in Primary Hypertensive Subjects Attending a Tertiary Hospital in Nigeria

DOI: 10.4236/ojbd.2023.132009, PP. 69-77

Keywords: Hypertension, Haematological Parameters, Tertiary Hospital, Nigeria

Full-Text   Cite this paper   Add to My Lib

Abstract:

Background: Hypertension is a persistent elevation of blood pressure in the arteries which if not properly managed can lead to stroke, heart failure, atrial fibrillation, peripheral vascular disease and other life threatening outcomes. This study investigated some haematological parameters of Primary hypertensive subjects. Objectives: To compare some haematological parameters (haematocrit, haemoglobin concentration, Platelets count, White Blood Cells count, red blood cell count and Red Cells Indices between hypertensive and normotensive subjects. Materials and methods: Blood samples were collected from 76 known hypertensive subjects between 30 - 70 years attending the Cardiology clinic of the University of Abuja Teaching Hospital Gwagwalada. Another 37 normotensive subjects between 30 - 65 years served as the control. All subjects gave their consents. Platelets count, Haemoglobin estimation, Packed Cell Volume, Red Blood Cell Count, Mean Cell Volume, Mean Cell Haemoglobin, Mean Cell Haemoglobin Concentration and White Blood Cell count were determined using Mythic 22 five parts haematology analyzer. Results: Results for Hypertensive and Control subjects were, White Blood Cell, 5.76 ± 1.45 × 109/l and 4.76 ± 1.03 × 109/l, Platelet count, 248.7552.45 × 109/l and 284.95 ± 27.66 × 109/l, Mean Cell Volume, 91.81 ± 3.05 fl and 85.68 ± 6.48

References

[1]  Carretero, O.A. and Oparil, S. (2000) Essential Hypertension. Part I: Definition and Etiology. Circulation, 101, 329-335.
https://doi.org/10.1161/01.CIR.101.3.329
[2]  Kearney, P.M., Whelton, M., Reynolds, K., Muntner, P., Whelton, P.K. and He, J. (2005) Global Burden of Hypertension: Analysis of Worldwide Data. The Lancet, 365, 217-223.
https://doi.org/10.1016/S0140-6736(05)17741-1
[3]  Damilola, O. (2018) Hypertension Affects about One Third of Nigerians. To What Social Stratum Patients belong Makes a Difference in How They Handle Their Condition. Last Contributed to D+C/E+Z in Spring of 2018 as Senior Correspondent at THISDAY Newspaper in Abuja, Nigeria.
[4]  Boos, C.J. and Lip, G.Y. (2005) Elevated High-Sensitive C-Reactive Protein, Large Arterial Stiffness and Atherosclerosis: A Relationship between Inflammation and Hypertension? Journal of Human Hypertension, 19, 511-513.
https://doi.org/10.1038/sj.jhh.1001858
[5]  Shankar, A., Barbara, E.K. and Klein, R. (2004) Relationship between White Blood Cell Count and Incident Hypertension. American Journal of Hypertension, 17, 233-239.
https://doi.org/10.1016/j.amjhyper.2003.11.005
[6]  Bao, W., Dalferes, E.R., Srinivasan, S.R., Webber, L.S. and Berenson, G.S. (1993) Normative Distribution of Complete Blood Count from Early Childhood through Adolescence: The Bogalusa Heart Study. Preventive Medicine, 22, 825-837.
https://doi.org/10.1006/pmed.1993.1075
[7]  Rampling, M.W. (1999) Haemorheological Disturbances in Hypertension: The Influence of Diabetes and Smoking. Clinical Hemorheology and Microcirculation, 21, 183-187.
[8]  Sandhagen, B. (1999) Red Cell Fluidity in Hypertension. Clinical Hemorheology Microcirculation, 21, 179-181.
[9]  Kawamoto, R., Tabara, Y., Kohara, K., Miki, T., Kusunoki, T., Katoh, T., Ohtsuka, N., Takayama, S. and Abe, M. (2012) A Slightly Low Hemoglobin Level Is Beneficially Associated with Arterial Stiffness in Japanese Community-Dwelling Women. Clinical and Experimental Hypertension, 34, 92-98.
https://doi.org/10.3109/10641963.2011.618202
[10]  Kanbay, M., Akcay, A., Delibasi, T., Uz, B., Kaya, A. and Koca, C. (2007) Comparison of Effects of Darbepoetin Alfa and Epoetin Alfa on Serum Endothelin Level and Blood Pressure. Advances in Therapy, 24, 346-352.
https://doi.org/10.1007/BF02849903
[11]  Berridge, M.J. (2014) Module 11: Cell Stress, Inflammatory Responses and Cell Death. Cell Signaling Biology, 14, 261-289.
https://doi.org/10.1042/csb0001011
[12]  Brown, D., Giles, W.H. and Croft, J.B. (2001) White Blood Cell Count: An Independent Predictor of Coronary Heart Disease Mortality among a National Cohort. Journal of Clinical Epidemiology, 54, 316-322.
https://doi.org/10.1016/S0895-4356(00)00296-1
[13]  Kim, D.J., Noh, J.H., Lee, B.W., Choi, Y.H., Chung, J.H. and Min, Y.K. (2008) The Associations of Total and Differential White Blood Cell Counts with Obesity, Hypertension, Dyslipidemia and Glucose Intolerance in a Korean Population. Journal of Korean Medical Science, 23, 193-198.
https://doi.org/10.3346/jkms.2008.23.2.193
[14]  Babu, K.R., Kumar, N.L.G., Solepure, A.B. and Shaikh, R. (2015) Comparison of Haematological Parameters in Primary Hypertensives and Normotensives of Sangareddy. International Journal of Biomedical Research, 6, 309-315.
https://doi.org/10.7439/ijbr.v6i5.1994
[15]  Jadeja, U., Jadeja, J. and Naik, S. (2011) Comparative Study of Haemoglobin Concentration in Hypertensive and Normotensive Subjects. Indian Journal of Applied Basic Medical Sciences, 13, 7.
[16]  Reis, R.S., Bensenor, I.J. and Lotufo, P.A. (1999) Laboratory Assessment of the Hypertensive Individual. Value of the Main Guidelines for High Blood Pressure. Arquivos Brasileiros de Cardiologia, 73, 201-210.
https://doi.org/10.1590/S0066-782X1999000800008
[17]  Smebye, M.L., Iversen, E.K., Høieggen, A., Flaa, A., Os, I. and Kjeldsen, S.E. (2007) Effect of Hemoglobin Levels on Cardiovascular Outcomes in Patients with Isolated Systolic Hypertension and Left Ventricular Hypertrophy (from the LIFE Study). American Journal of Cardiology, 100, 855-859.
https://doi.org/10.1016/j.amjcard.2007.03.109
[18]  Karabulut, A. and Karadag, A. (2015) Clinical Implication of Hematological Indices in the Essential Hypertension. World Journal of Hypertension, 5, 93-97.
https://doi.org/10.5494/wjh.v5.i2.93
[19]  Schillaci, G., Pirro, M., Pucci, G., Ronti, T., Vaudo, G., Mannarino, M.R., Porcellati, C. and Mannarino, E. (2018) Prognostic Value of Elevated White Blood Cell Count in Hypertension. American Journal of Hypertension, 20, 364-369.
https://doi.org/10.1016/j.amjhyper.2006.10.007
[20]  Inanc, T., Kaya, M.G., Yarlioglues, M., Ardic, I., Ozdogru, I. and Dogan, A. (2010) The Mean Platelet Volume in Patients with Non-Dipper Hypertension Compared to Dippers and Normotensives. Blood Pressure, 19, 81-85.
https://doi.org/10.3109/08037050903516284
[21]  Bamlaku, E., Nigist, A., Betelihem, T., Fikir, A. and Mulugeta, M. (2017) A Comparative Cross-Sectional Study of Some Hematological Parameters of Hypertensive and Normotensive Individuals at the University of Gondar Hospital, Northwest Ethiopia. Boston Medical Center Hematology, 17, 93-99.
https://doi.org/10.1186/s12878-017-0093-9

Full-Text

Contact Us

service@oalib.com

QQ:3279437679

WhatsApp +8615387084133