从补虚化瘀论治糖尿病肾病及相关研究
Study on the Treatment of Diabetic Nephropathy from Tonifying Deficiency and Removing Stasis

糖尿病肾病的发病率逐年增加，研究其复杂的发病机制，有效治疗本病是医学界研究的热点。中医学认为脏腑虚损是引起糖尿病肾病的内在原因，瘀血作为糖尿病肾病主要的致病因素及病理产物贯穿于本病的始终，形成瘀的关键因素是虚，涉及脏腑本虚、阴虚、气阴两虚及阳虚。现代医学认为血流动力学改变是导致糖尿病肾病的重要机制之一，也从中医治疗糖尿病肾病的思路中发现中医瘀血理论与血流动力学改变密切相关。本文通过阐述“虚”、“瘀”是糖尿病肾病致病因素，结合“瘀血”的现代研究，提出补虚化瘀同治的治疗原则，以及对应用补虚化瘀法治疗糖尿病肾病的临床研究进行概述。
The incidence rate of diabetes nephropathy has increased year by year. Studying its complex pa-thogenesis and effective treatment of this disease is a hot topic in medical research. Traditional Chinese medicine believes that the deficiency of viscera is the internal cause of diabetes nephro-pathy. Diabetes is the main pathogenic factor and pathological product of diabetic nephropathy throughout the disease. The key factor of stasis is deficiency, which involves the deficiency of Zang Fu organs, yin deficiency, Qi Yin deficiency and yang deficiency. Modern medicine considers hemodynamic changes as one of the important mechanisms of diabetes nephropathy. It is also found that the theory of blood stasis in TCM is closely related to hemodynamic changes in the treatment of diabetes nephropathy. This article expounds the deficiency of diabetes and the pathogenesis of diabetes nephropathy. Combining the modern research of “blood stasis”, it puts forward the principles of treating deficiency and removing stasis and treating the same disease, and summarizes the clinical research of treating diabetes nephropathy by reinforcing deficiency and removing blood stasis.