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人工关节假体周围感染的抗生素应用
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Abstract:
人工关节置换术已经改善了世界各地数百万人的生活。该手术的效果包括功能恢复和疼痛减轻。人工关节假体周围感染(Periprosthetic joint infection, PJI)目前仍然是人工关节翻修术最常见的原因之一。因PJI感染复发率较高，故假体周围感染常伴随着长期反复的治疗，对患者及其家属带来极大的痛苦与经济负担。同时假体周围感染的病原菌常为耐药菌且常伴有多种病原菌的混合感染，故治疗难度较高。治疗感染抗生素的应用尤为重要，因此本文将结合国内外最新的指南以及相关的研究成果，对假体周围感染的抗生素应用进行总结和归纳，对骨科医生治疗假体周围感染给予一定的帮助。
Artificial joint replacement has improved the lives of millions of people around the world. The re-sults of the procedure include functional recovery and pain reduction. Periprosthetic joint infection (PJI) remains one of the most common causes of revision surgery. Because of the high recurrence rate of PJI infection, periprosthesis infection is often accompanied by long-term repeated treatment, which brings great pain and economic burden to patients and their families. At the same time, the pathogens around the prosthesis infection are often drug-resistant bacteria and often accompanied by a variety of pathogens mixed with infection, so the treatment is relatively difficult. The applica-tion of antibiotics in the treatment of infection is particularly important. Therefore, this paper will combine the latest domestic and foreign guidelines and relevant research results to summarize and conclude the application of antibiotics in the treatment of periprosthesis infection, so as to give cer-tain help to orthopedic surgeons in the treatment of periprosthesis infection.
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