|
|
呼吸支持技术在新生儿呼吸窘迫综合征中的应用
|
Abstract:
新生儿呼吸窘迫综合征是新生儿尤其是早产儿出生后常见的呼吸系统疾病，也是导致新生儿死亡的重要原因之一。外源性肺泡表面物质联合呼吸机辅助通气是目前公认的针对新生儿呼吸窘迫综合征的核心治疗措施，该措施可以减少病死率及改善晚期预后。本文拟从新生儿呼吸窘迫综合征的病因、肺泡表面活性物质及辅助呼吸技术三个方面着手，对新生儿呼吸窘迫综合征的呼吸支持策略进行综述。
Neonatal respiratory distress syndrome (NRDS) is a common respiratory disease in newborns, es-pecially premature infants, and one of the main causes of neonatal death. It is acknowledged that exogenous surfactant therapy combined with ventilation support was the core treatment measure for NRDS and it can reduce the mortality and improve late outcomes. In this paper, respiratory support strategies for neonatal respiratory distress syndrome were reviewed from three aspects: etiology of neonatal respiratory distress syndrome, alveolar surfactant and assisted respiratory techniques.
| [1] | Lawn, J.E., Blencowe, H., et al. (2014) Every Newborn: Progress, Priorities, and Potential beyond Survival. The Lancet, 384, 189-205. https://doi.org/10.1016/S0140-6736(14)60496-7 |
| [2] | Sweet, D.G., Carnielli, V., et al. (2019) Euro-pean Consensus Guidelines on the Management of Respiratory Distress Syndrome—2019 Update. Neonatology, 115, 432-450. https://doi.org/10.1159/000499361 |
| [3] | Anadkat, J.S., Kuzniewicz, M.W., et al. (2012) Increased Risk for Respiratory Distress among White, Male, Late Preterm and Term Infants. Journal of Perinatology, 32, 780-785. https://doi.org/10.1038/jp.2011.191 |
| [4] | Grandi, C., Tapia, J.L., et al. (2015) Impact of Maternal Diabetes Mellitus on Mortality and Morbidity of Very Low Birth Weight Infants: A Multicenter Latin America Study. The Journal of Pedi-atrics (Rio J), 91, 234-241.
https://doi.org/10.1016/j.jped.2014.08.007 |
| [5] | Sardesai, S., Biniwale, M., et al. (2017) Evolution of Surfactant Therapy for Respiratory Distress Syndrome: Past, Present, and Future. Pediatric Research, 81, 240-248. https://doi.org/10.1038/pr.2016.203 |
| [6] | Verder, H., Agertoft, L., et al. (1992) Surfactant Treatment of Newborn Infants with Respiratory Distress Syndrome Primarily Treated with Nasal Continuous Positive Air Pressure. A Pilot Study. Ugeskrift for Laeger, 154, 2136-2139. |
| [7] | Aldana-Aguirre, J.C., Pinto, M., et al. (2017) Less Invasive Surfac-tant Administration versus Intubation for Surfactant Delivery in Preterm Infants with Respiratory Distress Syndrome: A Systematic Review and Meta-Analysis. Archives of Disease in Childhood. Fetal and Neonatal Edition, 102, F17-F23. https://doi.org/10.1136/archdischild-2015-310299 |
| [8] | Xu, C.C., Bao, Y.Y., et al. (2022) Effects of Less Invasive Surfactant Administration versus Intubation-Surfactant- Extubation on Bronchopulmonary Dysplasia in Preterm Infants with Respiratory Distress Syndrome: A Single-Center, Retrospective Study from China. BMC Pulmonary Medicine, 22, 462. https://doi.org/10.1186/s12890-022-02270-x |
| [9] | Guthrie, S.O. and Cummings, J.J. (2020) Not Sure? How Should We Give Exogenous Surfactant to Newborns with RDS? Pediatric Pulmonology, 55, 14-16. https://doi.org/10.1002/ppul.24543 |
| [10] | Wang, J., Liu, X., et al. (2015) Analysis of Neonatal Respiratory Distress Syndrome among Different Gestational Segments. International Journal of Clinical and Experimental Medicine, 8, 16273-16279. |
| [11] | Chen, C.Y., Chou, A.K., et al. (2017) Quality Improvement of Nasal Continuous Positive Airway Pressure Therapy in Neonatal Intensive Care Unit. Pediatrics & Neonatology, 58, 229-235. https://doi.org/10.1016/j.pedneo.2016.04.005 |
| [12] | Lemyre, B., Laughon, M., et al. (2016) Early Nasal Intermittent Positive Pressure Ventilation (NIPPV) versus Early Nasal Continuous Positive Airway Pressure (NCPAP) for Preterm Infants. Cochrane Database of Systematic Reviews, 12, CD005384. https://doi.org/10.1002/14651858.CD005384.pub2 |
| [13] | Li, W., Long, C., et al. (2015) Nasal Intermittent Positive Pressure Ventilation versus Nasal Continuous Positive Airway Pressure for Preterm Infants with Respiratory Distress Syndrome: A Meta-Analysis and Up-Date. Pediatric Pulmonology, 50, 402-409. https://doi.org/10.1002/ppul.23130 |
| [14] | Gharehbaghi, M.M., Hosseini, M.B., et al. (2019) Comparing the Efficacy of Nasal Continuous Positive Airway Pressure and Nasal Intermittent Positive Pressure Ventilation in Early Management of Respiratory Distress Syndrome in Preterm Infants. Oman Medical Journal, 34, 99-104. https://doi.org/10.5001/omj.2019.20 |
| [15] | Cimino, C., Saporito, M.A.N., et al. (2020) N-BiPAP vs n-CPAP in Term Neonate with Respiratory Distress Syndrome. Early Human Development, 142, Article ID: 104965. https://doi.org/10.1016/j.earlhumdev.2020.104965 |
| [16] | Zhou, B., Zhai, J.F., et al. (2015) Usefulness of DuoPAP in the Treatment of Very Low Birth Weight Preterm Infants with Neonatal Respiratory Distress Syndrome. European Review for Medical and Pharmacological Sciences, 19, 573-577. |
| [17] | Sadeghnia, A., Barekateyn, B., et al. (2016) Analysis and Comparison of the Effects of N-BiPAP and Bubble-CPAP in Treatment of Preterm Newborns with the Weight of below 1500 Grams Affiliated with Respiratory Distress Syndrome: A Randomised Clinical Trial. Advanced Biomedical Research, 5, 3. https://doi.org/10.4103/2277-9175.174965 |
| [18] | Murki, S., Singh, J., et al. (2018) High-Flow Nasal Cannula versus Nasal Continuous Positive Airway Pressure for Primary Respiratory Support in Pre-term Infants with Respiratory Distress: A Randomized Controlled Trial. Neonatology, 113, 235-241. https://doi.org/10.1159/000484400 |
| [19] | Wilkinson, D., Andersen, C., et al. (2016) High Flow Nasal Cannula for Respiratory Support in Preterm Infants. Cochrane Database of Systematic Reviews, 2, CD006405. https://doi.org/10.1002/14651858.CD006405.pub3 |
| [20] | Bruet, S., Butin, M., et al. (2022) Systematic Review of High-Flow Nasal Cannula versus Continuous Positive Airway Pressure for Primary Support in Preterm Infants. Archives of Disease in Childhood. Fetal and Neonatal Edition, 107, 56-59. https://doi.org/10.1136/archdischild-2020-321094 |
| [21] | Conte, F., Orfeo, L., et al. (2018) Rapid Systematic Review Shows That Using a High-Flow Nasal Cannula Is Inferior to Nasal Continuous Positive Airway Pressure as First-Line Support in Preterm Neonates. Acta Paediatrica, 107, 1684-1696. https://doi.org/10.1111/apa.14396 |
| [22] | Colleti Junior, J., Azevedo, R., et al. (2020) High-Flow Nasal Cannula as a Post-Extubation Respiratory Support Strategy in Preterm Infants: A Systematic Review and Meta-Analysis. The Journal of Pediatrics (Rio J), 96, 422-431.
https://doi.org/10.1016/j.jped.2019.11.004 |
| [23] | Firestone, K.S., Beck, J., et al. (2016) Neurally Adjusted Ventila-tory Assist for Noninvasive Support in Neonates. Clinics in Perinatology, 43, 707-724. https://doi.org/10.1016/j.clp.2016.07.007 |
| [24] | Vignaux, L., Grazioli, S., et al. (2013) Patient-Ventilator Asyn-chrony during Noninvasive Pressure Support Ventilation and Neurally Adjusted Ventilatory Assist in Infants and Chil-dren. Pediatric Critical Care Medicine, 14, e357-e364.
https://doi.org/10.1097/PCC.0b013e3182917922 |
| [25] | Kallio, M., Mahlman, M., et al. (2019) NIV NAVA versus Nasal CPAP in Premature Infants: A Randomized Clinical Trial. Neonatology, 116, 380-384. https://doi.org/10.1159/000502341 |
| [26] | Parashar, N., Amidon, M., et al. (2019) Noninvasive Neurally Adjusted Ventilatory Assist versus High Flow Cannula Support after Congenital Heart Surgery. World Journal for Pediatric and Congenital Heart Surgery, 10, 565-571.
https://doi.org/10.1177/2150135119859879 |
| [27] | F. Committee on Newborn, et al. (2014) Respiratory Support in Preterm Infants at Birth. Pediatrics, 133, 171-174.
https://doi.org/10.1542/peds.2013-3442 |
| [28] | Liu, C.Z., Huang, B.Y., et al. (2016) Efficacy of Volume-Targeted Ventilation for the Treatment of Neonatal Respiratory Distress Syndrome. Chinese Journal of Contemporary Pediatrics, 18, 6-9. |
| [29] | Klingenberg, C., Wheeler, K.I., et al. (2017) Volume-Targeted versus Pressure-Limited Ventilation in Ne-onates. Cochrane Database of Systematic Reviews, 10, CD003666. https://doi.org/10.1002/14651858.CD003666.pub4 |
| [30] | Cools, F., Offringa, M., et al. (2015) Elective High Fre-quency Oscillatory Ventilation versus Conventional Ventilation for Acute Pulmonary Dysfunction in Preterm Infants. Cochrane Database of Systematic Reviews, 3, CD000104.
https://doi.org/10.1002/14651858.CD000104.pub4 |
| [31] | Yao, Y.T. and Shi, Y. (2022) Efficacy of Vol-ume-Targeted Ventilation versus High-Frequency Oscillatory Ventilation in the Treatment of Neonatal Respiratory Dis-tress Syndrome. Chinese Journal of Contemporary Pediatrics, 24, 1321-1325. |
| [32] | Zhu, X., Qi, H., et al. (2022) Non-invasive High-Frequency Oscillatory Ventilation vs Nasal Continuous Positive Airway Pressure vs Nasal Intermittent Positive Pressure Ventilation as Postextubation Support for Preterm Neonates in China: A Randomized Clinical Trial. JAMA Pediatrics, 176, 551-559.
https://doi.org/10.1001/jamapediatrics.2022.0710 |
| [33] | Pan, S. and Zhang, Z. (2020) Less Invasive Surfactant Ad-ministration Combined with Nasal High Frequency Oscillatory Ventilation for an Extremely Low Birth Weight Infant with Severe Hypercapnia: A Case Report. Medicine (Baltimore), 99, e22796. https://doi.org/10.1097/MD.0000000000022796 |
| [34] | Zhu, X., Feng, Z., et al. (2021) Nasal High-Frequency Os-cillatory Ventilation in Preterm Infants with Moderate Respiratory Distress Syndrome: A Multicenter Randomized Clini-cal Trial. Neonatology, 118, 325-331.
https://doi.org/10.1159/000515226 |
