中药防治抑郁症的研究进展
Research Progress of Depression Prevention and Treatment with Chinese Medicine

抑郁症是一种常见且严重的精神疾病，临床表现为情绪低落、思维迟缓、意志活动、减退嗜睡、食欲减退、疲劳乏力、性欲减退、失眠等，甚者自杀。其患者的功能残疾程度高于糖尿病、高血压、冠状动脉疾病或关节炎等慢性疾病患者。预计到2030年抑郁症成为世界第二大疾病。目前抑郁症的发病机制尚未定论。临床以西药为主的抗抑郁药，出现时效长，疗效差，副作用明显等问题。而中药在中医辨证与整体的指导思路下，因多靶点、多途径、整体调节且不良反应小的特点，医生和患者逐渐接受中医药治疗。本文主要探讨抑郁症在常用中药的组方、单药和中药提取化合物的治疗方面的研究进展，为未来对其进行深入研究可为抗抑郁治疗提供新思路。
Depression is a common and serious mental disease, with clinical manifestations such as depressed mood, slow thinking, willpower activity, decreased drowsiness, decreased appetite, fatigue, de-creased libido, insomnia, and even suicide. Their patients had a higher degree of functional disabil-ity than those with chronic conditions such as diabetes, hypertension, coronary artery disease or arthritis. Depression is expected to become the world’s second largest disease by 2030. At present, the pathogenesis of depression has not yet been determined. Antidepressants, which are mainly western medicine in clinic, have such problems as long time effect, poor curative effect, obvious side effects, etc. Under the guidance of TCM syndrome differentiation and holism, doctors and patients of traditional Chinese medicine (TCM) are gradually receiving TCM treatment due to the characteris-tics of multiple targets, multiple pathways, overall regulation and small adverse reactions. This pa-per mainly discusses the research progress of depression in the treatment of commonly used tradi-tional Chinese medicine (TCM) formula, single drug and Chinese medicine extract compounds, to provide new ideas for further research and antidepressant treatment in the future.