Natural Nanoskin Advance cell therapy (ACT) and Nanoskin ACT Soft have been established to be remarkably versatile biomaterials and can be used in a wide variety of applied scientific endeavors, especially for medical devices. In fact, the structure of Nanoskin materials can be adapted over length scales ranging from nano to macro by controlling the bio-fabrication process. The present paper describes Natural Nanoskin Advanced cell therapy (ACT) and Nanoskin ACT Soft production for wound care applications. ACT is produced from the bio-nanotechnology process. ACT is a highly hydrated pellicle with shaped fibers less than 2 nm wide. Nanoskin ACT Soft, like a paste, is designed to fill irregularities or recesses in the wound bed, and to absorb excess exudate from lesions by prolonging the used dressing's residence time and reducing the frequency of change.
References
[1]
Rayner, R., Carville, K., Keaton, J., Prentice, J. and Santamaria, X.N. (2009) Leg Ulcers: Atypical Presentations and Associated Comorbidities. Wound Practice and Research, 17, 168-185.
[2]
Rahman, G.A., Adigun, I.A. and Fadeyi, A. (2010) Epidemiology, Etiology, and Treatment of Chronic Leg Ulcer: Experience with Sixty Patients. Annals of African Medicine, 9, 1-4. https://doi.org/10.4103/1596-3519.62615
[3]
Faria, E., Blanes, L., Hochman, B., Filho, M.M. and Ferreira, L. (2011) Health-Related Quality of Life, Self-Esteem, and Functional Status of Patients with Leg Ulcers. Wounds, 23, 4-10.
[4]
Siddiqui, A.R. and Bernstein, J.M. (2010) Chronic Wound Infection: Facts and Controversies. Clinics in Dermatology, 28, 519-526. https://doi.org/10.1016/j.clindermatol.2010.03.009
[5]
Han, A., Zenilman, J.M., Melendez, J.H., Shirtliff, M.E., Agostinho, A., James, G., Stewart, P.S., Mongodin, E.F., Rao, D., Rickard, A.H. and Lazarus, G.S. (2011) The Importance of a Multi-Faceted Approach to Characterizing the Microbial Flora of Chronic Wounds. Wound Repair and Regeneration, 19, 532-541. https://doi.org/10.1111/j.1524-475X.2011.00720.x
[6]
Olyveira, G.M., Costa, L.M.M., Riccardi, C.S., Santos, M.L., Daltro, P.B., Basmaji, P., Daltro, G.C. and Guastaldi, A.C. (2016) Bacterial Cellulose for Advanced Medical Materials. In: Grumezescu, A.M., Ed., Nanobiomaterials in Soft Tissue Engineering, Elsevier, Romania, 57-82. https://doi.org/10.1016/B978-0-323-42865-1.00003-9
[7]
Olyveira, G.M., Santos, M.L., Riccardi, C.S., Costa, L.M.M., Daltro, P.B., Basmaji, P., Daltro, G.C. and Guastaldi, A.C. (2015) Bacterial Cellulose Biocomposites for Periodontology Treatment. Advanced Science, Engineering and Medicine, 7, 409-414. https://doi.org/10.1166/asem.2015.1641
[8]
Basmaji, P., Olyveira, G.M. and Costa, L.M.M. (2015) Nanoskin Extracellular Matrix Modified with Hyaluronic Acid and Chondroitin Sulfate for Regenerative Medicine Applications. Journal of Bionanoscience, 9, 306-310. https://doi.org/10.1166/jbns.2015.1304
[9]
Basmaji, P., Ambrizzi, D.R., Olyveira, G.M., Costa, L.M.M., Francozo, G.B. and Oliveira, J.D.C. (2016) Natural Extracellular Matrix Modified for Tissue Engineering Applications. Advanced Science, Engineering and Medicine, 8, 62-67. https://doi.org/10.1166/asem.2016.1817
[10]
Safi, B., Kanjou, M., De Olyveira, G., Basmaji, P. and Guastaldi A.C. (2022) Nanoskin?—The Impact of Natural Membrane on COVID-19 and Chronic Wound. Journal of Community Medicine and Public Health Reports, 3, 1-11.
[11]
Basmaji, P., Olyveira, G., Kanjou, M. and Reichert, H. (2022) Bacterial Cellulose for Several Medicine Areas: Future Insights. Materials Letters, 308, Article ID: 131109. https://doi.org/10.4236/jbnb.2022.131001
