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外科二尖瓣置换术中同时行左心耳闭合降低房颤有关缺血性脑卒中相关进展及研究
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Abstract:
心房颤动是心脏内形成血栓导致脑卒中的重要原因。目前主要的预防房颤相关脑卒中的措施为抗凝药物治疗，这种方法虽然降低了缺血性脑卒中的风险却增加了严重的出血风险。左心耳的闭合术已经发展为能够将左心耳与心脏内血液循环流动分离开来，且有多项研究也显示，左心耳闭合可以有效地降低术后心房颤动引发的脑卒中相关风险系数，且被多项实验及研究证明与抗凝治疗相比有相似的效果。心脏手术中同期行左心耳闭合更是提供了心脏术后除传统的口服抗凝药物治疗外的另一种安全、有效的选择。
Atrial fibrillation is an important cause of cardioembolic stroke. Anticoagulation is the mainstay of stroke prevention in patients with atrial fibrillation. Oral anticoagulants (OAC) reduce stroke risk but increase the risk of serious bleeding. Left atrial appendage (LAA) procedures have been devel-oped to isolate the LAA from circulating blood flow, and many studies have proved that Left Atrial Appendage Occlusion has the the same effect as OAC and has become an alternative as a treatmnet besides OAC after cardiac surgery.
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