Objective:
To study the epidemiological, clinical and therapeutic aspects of sickle cell disease in children admitted to
the pediatric emergency department of the Gabriel Toure University Hospital.
Materials and methods: This was a prospective study over 12 months in sickle
cell children aged 6 months to 15 years. Results: The frequency of sickle cell
disease was 4.67% with
71.1% of SS form. The age range of 60-120
months predominated with 43.4% and the sex ratio 1.4. Vaso-occlusive crises
(VOC) were the most frequent reason for consultation (50.6%) and osteoarticular
pain was the main symptom followed by fever and pallor with respectively 67.5%,
60.2%, 39.8%. The pain subsided in less than 72 hours in 39.8% and hyper
hydration was performed in 85.1% of patients. Analgesic treatment was given in
90.4%, antibiotic therapy in 51.8% and phenotyped red blood cells transfusion
was performed in 36.1%. The average duration of treatment was 10 days.
Conclusion: Vaso-occlusive crisis remains the main reason for consultation in
sickle cell disease children at Gabriel Toure University Hospital. The
management consisted, in addition to the correction of the triggering factors,
of hyper hydration and the administration of analgesics and blood products.
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