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评估卵巢反应性指标的研究进展
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Abstract:
控制性超促排卵是辅助生殖技术中的重要环节，在控制性超促排卵过程中的卵巢反应性与助孕的安全性及成功率相关。因此，卵巢反应性是在IVF治疗中最常研究和关注的参数之一。在过去，众多学者应用多种生物标志物用于评估卵巢反应，但这些指标在临床中的应用价值有限。后续一直有学者不断提出新的指标以正确评估卵巢反应和改善周期结局，比如卵泡输出率，卵泡敏感指数和卵巢反应预测指数等组合因子指标。新提出的组合因子在卵巢反应性的评估方面各有优势，故结合目前的研究现状，对新提出的卵巢反应性评估的指标进行综述。
Controlled ovarian hyperstimulation is an integral part of assisted reproductive technology, ovarian responsiveness during controlled ovulation is associated with the safety and success of assisted conception. Therefore, ovarian responsiveness is one of the most frequently studied parameters in IVF treatment. In the past, many scholars have applied various biomarkers to assess ovarian re-sponse, but the value of these indicators in clinical practice has been limited. Subsequently, new metrics have been proposed to properly assess ovarian response and improve cycle outcomes, such as follicular output rate, follicular sensitivity index and ovarian response prediction index, among other combination factors. Since each of the newly proposed combination factors has advantages in assessing ovarian responsiveness, the freshly proposed indexes for ovarian responsiveness assess-ment are reviewed in the context of the current research status.
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