Known for their role in the manufacture of
eco-materials in buildings, Parkia biglobosa fruit husks are also used
in folk medicine. The present study focuses on the metabolites content and
antiradical, antibacterial activities of the hydroethanolic extract of P.
biglobosa husks. Secondary metabolites were identified using staining
and/or precipitation tests. The mineral content is determined according to the
standard NF EN 14082. The antioxidant activity performed by
2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging capacity, and antibacterial
activity strain against three Gram-negative and two Gram-positive strains by
microdilution for Minimal Inhibitory Concentration. Fruit husks contain
tannins, anthocyanins, leuco-anthocyanins, anthraquinones, saponins, reducing
compounds, sterols, terpenes, and 1.225% of potassium. The hydroethanolic
extract of P. biglobosa fruit husks scavenges the DPPH radical with an
EC50 = 64 μg/ml. The extract is more active in one Gram ？(Pseudomonas aeruginosa and Escherichia
coli) with a minimum inhibitory concentration of 1.25 mg/mL than the three
Gram + studied. This study showed that P. biglobosa fruit husks extract
could be used for its antioxidant and antibacterial activities.
References
[1]
Akoègninou, A., Van der Burg, W.J. and Van der Maesen, L.J.G. (2006) Flore analytique du Bénin. Many Line Drawings. XXII, 1034 p.
[2]
Balogun, W.G., Adebayo, I.A., Yusuf, U. and Seeni, A. (2018) A Review of the Phytochemistry and Medicinal Activities of the Popular African Food Additive: Parkia biglobosa Seed. Oriental Pharmacy and Experimental Medicine, 18, 271-279.
https://doi.org/10.1007/s13596-018-0337-7
[3]
Fifamè, G.N.V., Abiodoun, O.P., Adam, A.D., Goué, A.G., Virgile, B.A.E., et al. (2016) A Review on Medicinal Plants of Parkia biglobosa (Mimosaceae-Fabaceae) and Pterocarpus erinaceus (Leguminosae-Papilionoidea). Journal of Medicinal Plants Studies, 4, 132-137.
[4]
Azokpota, P., Hounhouigan, D.J. and Nago, M.C. (2006) Microbiological and Chemical Changes during the Fermentation of African Locust Bean (Parkia biglobosa) to Produce afitin, iru and sonru, Three Traditional Condiments Produced in Benin. International Journal of Food Microbiology, 107, 304-309.
https://doi.org/10.1016/j.ijfoodmicro.2005.10.026
[5]
Modupe, O., James, O.A. and Adesola, A. (2016) The Study of the Effect of Moisture Content on the Biochemical Deterioration of Stored Fermented Parkia biglobosa Seeds. Open Journal of Engineering Research and Technology, 1, 14-22.
[6]
Compaoré, S.C., Tapsoba, F.W., Parkouda, C., Tamboura, D., Traoré, E.M.A., et al. (2020) Development of Starter Cultures Carrier for the Production of High-Quality Soumbala, a Food Condiment Based on Parkia biglobosa Seeds. African Journal of Biotechnology, 19, 820-828. https://doi.org/10.5897/AJB2020.17244
[7]
Modupe, E.O., Benjamen, E., Ayodeji, A.A., Ajibola, T.O., et al. (2017) Termiticidal Effects of African Locust Bean (Parkia biglobosa) Seed Oil Extract. International Journal of Current Research, 9, 53929-53934.
[8]
Termote, C., Odongo, N.O., Dreyer, B.S., Guissou, B., Parkouda, C. and Vinceti, B. (2022) Nutrient Composition of Parkia biglobosa Pulp, Raw and Fermented Seeds: A Systematic Review. Critical Reviews in Food Science and Nutrition, 62, 119-144.
https://doi.org/10.1080/10408398.2020.1813072
[9]
Olalude, C.B., Adegboyega, A.M., Bamigboye, A.Y., Abiona, D.L., Anifowose, O.A. and Babatunde, S.Y. (2021) Proximate Analysis and Mineral Content Determination of Traditionally Processed Locust Bean (Parkia biglobosa) Fruit Pulp for Possible Industrial Application. Edelweiss Chemical Science Journal, 4, 10-13.
https://doi.org/10.33805/2641-7383.124
[10]
Adama, A.Y., Jimoh, Y.A. and Kolo, S.S. (2013) Effect of Locust Bean Pod Ash on Compaction Characteristics of Weak Sub Grade Soils. International Journal of Engineering Science Invention, 2, 27-34.
[11]
Banakinao, S., Tiem, S., Lolo, K., Koutsawa, Y. and Bedja, K.S. (2016) Dataset of the Use of Tannin of Néré (Parkia-biglobosa) as a Solution for the Sustainability of the soil Constructions in West Africa. Data in Brief, 8, 474-483.
https://doi.org/10.1016/j.dib.2016.05.072
[12]
Abagale, S.A., Twumasi, S.K. and Awudza, J. (2020) Chemical Analyses of Parkia biglobosa Fruit Husk Extract and Lateritic Soil Used in Ethnobotanical Preparation of Mud Wall Plaster in Some West African Countries. AASCIT Journal of Chemistry, 6, 14-19.
[13]
Aguwa, J.I., Alhaji, B., Jiya, A. and Kareem, D.H. (2016) Effectiveness of Locust Bean Pod Solution (LBPS) in the Production of Sandcrete Blocks for Buildings. Nigerian Journal of Technological Development, 13, 13-16.
https://doi.org/10.4314/njtd.v13i1.3
[14]
Sorgho, B., Zerbo, L., Keita, I., Dembele, C., Plea, M., Sol, V., et al. (2014) Strength and Creep Behavior of Geomaterials for Building with Tannin Addition. Materials and Structures, 47, 937-946. https://doi.org/10.1617/s11527-013-0104-7
[15]
Kambou, G., Somé, N. and Ouedraogo, S. (2000) Effets des cosses de néré, Parkia biglobosa (Jacq.) R. Br. Ex. G. Ddon sur l’émergence du Striga hermonthica (Del.) Benth les propriétés agrochimiques du sol et le rendement du maïs. Bulletin de la Recherche Agronomique, 29, 16-30.
[16]
Jesse, Y., Sule, H. and Philip, C. (2006) Doruwa (Parkia biglobosa) Fruit Husk and Hyptis (Hyptis spicigera) Leaves for Controlling Root-Knot Nematodes (Meloidogyne incognita) in Tomato (Lycopersicon esculentum Mill C.V.) Journal of Tropical Agriculture, 44, 83-85.
[17]
Sereme, A., Millogo-Rasolodimby, J. and Guinko, S.N.M. (2008) Propriétés thérapeutiques des plantes à tanins du Burkina Faso. Pharmacopée Médecine Traditionnelle Africaines, 15, 41-49.
[18]
Dedehou, V., Olounladé, P., Adenilé, A., Azando, E., Alowanou, G., Daga, F., et al. (2014) Effets in vitro des feuilles de Pterocarpus erinaceus et des cosses de fruits de Parkia biglobosa sur deux stades du cycle de développement de Haemonchus contortus nématode parasite gastro-intestinal de petits ruminants. Journal of Animal and Plant Sciences, 22, 3368-3378.
[19]
Abagale Bagale, S.A., Twumasi, S.K. and Awudza, J.A.M. (2013) Chemical Analyses of Aqueous Extract of Parkia biglobosa Fruit Husk Collected from Northern Ghana. Scientific Research and Essays, 8, 589-595.
[20]
Salit, B.S., Emmanuel, U.O., Idongesit, J.M., Paul, N.O. and Labum, L. (2014) Parkia biglobosa Plants Parts: Phytochemical, Antimicrobial, Toxicity and Antioxidant Characteristics. Journal of Natural Science Research, 4, 130-133.
[21]
Sofowora, A., Ogunbodede, E. and Onayade, A. (2013) The Role and Place of Medicinal Plants in the Strategies for Disease Prevention. African Journal of Traditional, Complementary and Alternative Medicines, 10, 210-229.
https://doi.org/10.4314/ajtcam.v10i5.2
[22]
Bothon, F.T.D., Adovelande, J., Dossa, C.P.A., Avlessi, F., Wotto, D.V. and Sohounhloue, D.C.K. (2018) Phytochemical Study, Vitamins Content and Free Radical Scavenging Activity of Bixa orellana L. Leaves from Benin. Indo-American Journal of Pharmaceutical Sciences, 5, 9106-9113.
[23]
Aswathi, V.P. and Dhivya, R. (2017) Qualitative Phytochemical Screening and Mosquito Repellency of Chromolaena odorata (Asteraceae) Leaf Extract Against Adults of Culex quinquefasciatus (Diptera: Culicidae). Indo-American Journal of Pharmaceutical Sciences, 4, 698-705.
[24]
Atindehou, M., Lagnika, L., Guérold, B., Strub, J.M., Zhao M., Van Dorsselaer, A., et al. (2013) Isolation and Identification of Two Antibacterial Agents from Chromolaena odorata L. Active against Four Diarrheal Strains. Advances in Microbiology, 3, 115-121. https://doi.org/10.4236/aim.2013.31018
[25]
He, F.J. and MacGregor, G.A. (2008) Beneficial Effects of Potassium on Human Health. Physiologia Plantarum, 133, 725-735.
https://doi.org/10.1111/j.1399-3054.2007.01033.x
[26]
Houston, M.C. and Harper, K.J. (2008) Potassium, Magnesium, and Calcium: Their Role in Both the Cause and Treatment of Hypertension. Journal of Clinical Hypertension (Greenwich) 10, 3-11. https://doi.org/10.1111/j.1751-7176.2008.08575.x
[27]
Li, S., Medrano, J.A., Hessel, V. and Gallucci, F. (2018) Recent Progress of Plasma-Assisted Nitrogen Fixation Research: A Review. Processes, 6, Article 248.
https://doi.org/10.3390/pr6120248
[28]
Sroka, Z. (2005) Antioxidative and Antiradical Properties of Plant Phenolics. Zeitschrift für Naturforschung C, 60, 833-843.
https://doi.org/10.1515/znc-2005-11-1204
[29]
Benzidia, B., Barbouchi, M., Hammouch, H., Belahbib, N., Zouarhi, M., Erramli, H., et al. (2019) Chemical Composition and Antioxidant Activity of Tannins Extract from Green Rind of Aloe vera (L.) Burm. F. Journal of King Saud University: Science, 31, 1175-1181. https://doi.org/10.1016/j.jksus.2018.05.022
[30]
Glevitzky, I., Dumitrel, G.A., Glevitzky, M., Pasca, B., Otrisal, P., Bungau, S., et al. (2019) Statistical Analysis of the Relationship between Antioxidant Activity and the Structure of Flavonoid Compounds. Revista de Chimie, 70, 3103-3107.
https://doi.org/10.37358/RC.19.9.7497
[31]
Di Meo, S. and Venditti, P. (2020) Evolution of the Knowledge of Free Radicals and Other Oxidants. Oxidative Medicine and Cellular Longevity, 2020, Article ID: 9829176. https://doi.org/10.1155/2020/9829176
[32]
Ali, S., Alam, M., Hasan, G.M. and Hassan, M.I. (2022) Potential Therapeutic Targets of Klebsiella pneumoniae: A Multi-Omics Review Perspective. Briefings in Functional Genomics, 21, 63-77. https://doi.org/10.1093/bfgp/elab038
[33]
Pachori, P., Gothalwal, R. and Gandhi, P. (2019) Emergence of Antibiotic Resistance Pseudomonas aeruginosa in Intensive Care Unit; A Critical Review. Genes & Diseases, 6, 109-119. https://doi.org/10.1016/j.gendis.2019.04.001
[34]
Bonten, M., Johnson, J.R., Van Den Biggelaar, A.H.J., Georgalis, L., Geurtsen, J., De Palacios, P.I., et al. (2021) Epidemiology of Escherichia coli Bacteremia: A Systematic Literature Review. Clinical Infectious Diseases, 72, 1211-1219.
https://doi.org/10.1093/cid/ciaa210
[35]
Allocati, N., Masulli, M., Alexeyev, M.F. and Di Ilio, C. (2013) Escherichia coli in Europe: An Overview. International Journal of Environmental Research and Public Health, 10, 6235-6254. https://doi.org/10.3390/ijerph10126235
[36]
Da Silva, R.A.G., Tay, W.H., Ho, F.K., Tanoto, F.R., Chong, K.K.L., Choo, P.Y., et al. (2022) Enterococcus faecalis Alters Endo-Lysosomal Trafficking to Replicate and Persist within Mammalian Cells. PLoS Pathogens, 18, e1010434.
https://doi.org/10.1371/journal.ppat.1010434
[37]
Tong, S.Y.C., Davis, J.S., Eichenberger, E., Holland, T.L. and Fowler, V.G. (2015) Staphylococcus aureus Infections: Epidemiology, Pathophysiology, Clinical Manifestations, and Management. Clinical Microbiology Reviews, 28, 603-661.
https://doi.org/10.1128/CMR.00134-14
[38]
Keith, A.R. and Kevin, W.M. (2014) Methicillin-Resistant Staphylococcus aureus Therapy: Past, Present, and Future. Clinical Infectious Diseases, 58, S20-S27.
https://doi.org/10.1093/cid/cit614
[39]
Shima, M.A., Adebayo, O.S., Mark, P. and Nicol, M.K. (2015) Molecular Epidemiology of Methicillin-Resistant Staphylococcus aureus in Africa: A Systematic Review. Frontiers in Microbiology, 6, Article 348.
https://doi.org/10.3389/fmicb.2015.00348
[40]
Badmos, A.A., Adeyemi, K.D., Oyeyinka, S.A., Ahmed, R.N., et al. (2018) Effect of Parkia biglobosa Husk Extracts and Honey Blend on the Chemical, Sensory and Bacterial Attributes of Traditional West African Soft Cheese. Croatian Journal of Food Technology, Biotechnology and Nutrition, 13, 19-23.
https://doi.org/10.31895/hcptbn.13.1-2.5
[41]
Atanasov, A., Karadjova, V., Andonova, A., Tsekova, D., Lozanov, V., Parashkevova, B., et al. (2022) Synthesis, Isolation and Biological Activity Studies of Galanthamine Derivatives Including Peptide Moiety and Tannins from Medicinal Plants. Journal of Chemical Technology and Metallurgy, 57, 32-38.
[42]
Tagousop, C.N., Tamokou, J.-de-D., Kengne, I.C., Ngnokam, D. and Voutquenne-Nazabadioko, L. (2018) Antimicrobial Activities of Saponins from Melanthera elliptica and Their Synergistic Effects with Antibiotics against Pathogenic Phenotypes. Chemistry Central Journal, 12, Article No. 97.
https://doi.org/10.1186/s13065-018-0466-6
[43]
Khanna, V.G., Kuppusamy, A., Devarajan, S. and Kumar, K.K.A. (2019) Review on Medicinal Potential of Alkaloids and Saponins. Pharmacology OnLine, 1, 1-20.
