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Correlation of Abortus Imminence Cases in the First Trimester with Biochemical Markers

DOI: 10.4236/ojog.2023.132022, PP. 207-213

Keywords: Abortion, Biochemical Markers, Calcium, Copper, Magnesium, Missed Abor-tion, Spontaneous Abortion, Zinc

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Abstract:

Objective: In this study, we compared the biochemical markers of imminent abortion, missed abortion, and healthy pregnant women in the first trimester to see if there were any differences. Materials and Methods: The study method is prospective. Pregnant women who applied to the obstetrics clinic of Istanbul Training and Research Hospital between 01.04.22 and 31.10.22 were diagnosed with abortion imminens or missed abortion between 6 weeks and 12 weeks or had normal pregnancy follow-up, had no chronic diseases, and did not take magnesium and calcium supplements were included in the study. 20 pregnant women with missed abortion, 20 pregnant women with abortion imminens diagnosis and 20 normal pregnant women who met the criteria were included in the study. Magnesium (Mg), calcium (Ca), copper (Cu), zinc (Zn) and hemogram (CBC) levels were checked in pregnant women included in the study. Results: The Mg, Cu, Zn, and CBC values of the study participants women did not differ in a statistically significant way. When compared to pregnant women who had a normal pregnancy process, the difference in Ca value was found to be statistically substantially smaller in pregnant women who were diagnosed with abortion imminens and missed abortion. The findings of our study suggest that serum Ca levels be measured prior to conception or at the initial visit. Conclusion: Serum Ca levels were found to be significantly lower in the missed abortion group than in the abortus imminens and normal pregnant groups in our study (p < 0.05).

References

[1]  Cunningham, F.G., Leveno, K.J., Bloom, S.L., et al. (2020) Wıllıams Obstetrik 25.baskı. 18. Bölüm, ss: 350-356.
[2]  Scott, J.R., Disaia, P.J., Hammond, C.B. and Spellacy, W.N. (1999) Danforth’s Obstetrics and Gynecology. 8th Edition, Lippincott Williams & Wilkins, Philadelphia, 179.
[3]  Deniz, R., Baykuş, Y. and Kavak, E.Ç. (2016) Tekrarlayan erken gebelik kayıplarına yaklaşım; Kafkas üniversitesi Tıp Fakültesi, Kadın Hastalıkları ve Doğum Anabilim Dalı, Kars; Fırat üniversitesi Tıp Fakültesi, Kadın Hastalıkları ve Doğum Anabilim Dalı, Elazığ.
[4]  Durmuşoğlu, H., Paşaoğlu, Ö.T., Şen, B., et al. (2018) Gebelik Komplikasyonlarında Serum Çinko, Bakır ve Serüloplazminin Önemi. Firat Medical Journal, 23, 158-163.
[5]  Türkiye ye Özgü Beslenme Rehberi (TüBER) (2016) T.C. Sağlık Bakanlığı. Türkiye’ye Özgü Beslenme Rehberi. Sağlık Bakanlığı Yayınları. 2. Baskı.
[6]  DSÖ (2016) Avrupa Bölge Ofisi İyi Anne Beslenmesi Hayata En İyi Başlangıçtır.
https://www.euro.who.int/en/health-topics/disease
[7]  Paşaoğlu, H. (2017) Temel/Klinik Biyokimya. PelikanYayınevi; 193-212.
[8]  Rostan, E.F., DeBuys, H.V., Madey, D.L. and Pinnell, S.R. (2002) Evidence Supporting Zinc as an Important Antioxidant for Skin. International Journal of Dermatology, 41, 606-611.
https://doi.org/10.1046/j.1365-4362.2002.01567.x
[9]  Velie, E.M., Block, G.S., Shaw, G.M., et al. (1999) Maternal Supplemental and Dietary Zinc Intake and the Occurence of Neural Tube Defects in California. American Journal of Epidemiology, 150, 605-616.
https://doi.org/10.1093/oxfordjournals.aje.a010059
[10]  Olivares, M. and Uauy, R. (1996) Copper as an Essential Nutrient. The American Journal of Clinical Nutrition, 63, 791-796.
https://doi.org/10.1093/ajcn/63.5.791
[11]  Vukelić, J., Aleksandra, K.A., Petrović, D., et al. (2012) Variations of Serum Copper Values in Pregnancy. Srpski Arhiv za Celokupno Lekarstvo, 140, 42-46.
https://doi.org/10.2298/SARH1202042V
[12]  Skoog, D.A. and West, D.M. (1980) Principles of Instrumental Analysis. 2nd Edition, Saunders, Philadelphia, 169-197.
[13]  Sami, A.S., Suat, E., Ismet, A., et al. (2019) The Role of Trace Element, Mineral, Vitamin and Total Antioxidant Status in Women with Habitual Abortion. The Journal of Maternal-Fetal & Neonatal Medicine, 34, 1055-1062.
https://doi.org/10.1080/14767058.2019.1623872
[14]  Şahin, T.G., Mihmanlı, V., Çetinkaya, N., et al. (2013) Erken Doğum Tehdidi Olan Gebelerde Maternal Magnezyum, Kalsiyum ve C-reaktif Protein Seviyelerinin Değerlendirilmesi. Okmeydanı Tıp Dergisi, 29, 94-97.
[15]  Borella, P., Szilagyi, A., Than, G., et al. (1990) Maternal Plasma Concentrations of Magnesium, Calcium, Zinc and Copper in Normal and Pathological Pregnancies. Science of the Total Environment, 99, 67-76.
https://doi.org/10.1016/0048-9697(90)90212-D
[16]  Smolarczyk, R., Romejko, E., Wójcicka-Jagodzińska, J., et al. (1997) Homeostaza wapniowo-fosforanowo-magnezowa u kobiet z poronieniem zagrazajacym [Calcium-Phosphorus-Magnesium Homeostasis in Women with Threatened Abortion]. Ginekologia Polska, 68, 11-16.
[17]  Norman, J., Politz, D. and Politz, L. (2009) Hyperparathyroidism during Pregnancy and the Effect of Rising Calcium on Pregnancy Loss: A Call for Earlier Intervention. Clinical Endocrinology (Oxford), 71, 104-109.
https://doi.org/10.1111/j.1365-2265.2008.03495.x
[18]  Hirsch, D., Kopel, V., Nadler, V., et al. (2015) Pregnancy Outcomes in Women with Primary Hyperparathyroidism. The Journal of Clinical Endocrinology & Metabolism, 100, 2115-2122.
https://doi.org/10.1210/jc.2015-1110
[19]  Kasim, T., Ayşe, A., Kazim, U., et al. (2019) Change of the Levels of Trace Elements and Heavy Metals in Threatened Abortion. Journal of the Chinese Medical Association, 82, 7.
https://doi.org/10.1097/JCMA.0000000000000077
[20]  Omeljaniuk, J.W., Socha, K., Borawska, H.M., et al. (2015) Antioxidant Status in Women Who Have Had a Miscarriage. Advances in Medical Sciences, 60, 329-334.
https://doi.org/10.1016/j.advms.2015.06.003
[21]  Thaker, R., Oza, H., Shaikh, I. and Kumar, S. (2019) Correlation of Copper and Zinc in Spontaneous Abortion. International Journal of Fertility and Sterility, 13, 97-101.
[22]  Skalnaya, M.G., Tinkov, A.A., Lobanova, Y.N., Chang, J.S. and Skalny, A.V. (2019) Serum Levels of Copper, Iron, and Manganese in Women with Pregnancy, Miscarriage, and Primary Infertility. Journal of Trace Elements in Medicine and Biology, 56, 124-130.
https://doi.org/10.1016/j.jtemb.2019.08.009
[23]  Alvarez, I.S., Castañón, S.G., Ruata, M.L., et al. (2007) Updating of Normal Levels of Copper, Zinc and Selenium in Serum of Pregnant Women. Journal of Trace Elements in Medicine and Biology, 21, 49-52.
https://doi.org/10.1016/j.jtemb.2007.09.023
[24]  Wang, R., Zhang, L., Chen, Y., et al. (2020) Elevated Nonessential Metals and the Disordered Metabolism of Essential Metals Are Associated to Abnormal Pregnancy with Spontaneous Abortion. Environment International, 144, Article ID: 106061.
https://doi.org/10.1016/j.envint.2020.106061

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