Objectives: This study aimed to determine the correlation between waist circumference and
fatty liver on ultrasonography among non-alcoholic Filipino adults. This will aid in detecting non-alcoholic
fatty liver disease in its earlycourse, hence improving our current therapeutic recommendations in preventing and managing the adverse health outcomes of NAFLD. Methods and Materials: A cross-sectional study with a total of 65 recruited participants. The data
collected were age, sex, waist-circumference, co-morbidities with maintenance medications, history of alcohol
intake with emphasis on the quantity and duration, and history of drug intake.
Waist circumference was measured and recorded. The presence of NAFLD was
determined through a review of the ultrasonography results of all subjects. The
demographic profile and waist circumference
of all subjects were described using descriptive statistics. Thechi-square test was utilized to test the
independence of the NAFLD and WCin the quartile. Pearson correlation was used to determine
the linear relationship between the variables. Pearson correlation
coefficient was statistically significant at
p<0.05. Results: Among the subjects, 26 (42%)
presented with fatty liver based on ultrasonography, 15(58%) and 11(42%), males and females, respectively. The mean
waist circumference of 97.5±
References
[1]
Manuel, J.J., Elaine Palugod, M.D., et al. (2007) The Association of Risk Factors in the Development of Non-Alcoholic Fatty Liver Disease (NAFLD) in Filipino Patients with Type 2 Diabetes Mellitus in a Tertiary Center. Philippine Journal of Internal Medicine, 45, 135-143.
[2]
Younossi, Z.M, et al. (2017) The Economic and Clinical Burden of Nonalcoholic Fatty Liver Disease in the United States and Europe. Hepatology, 64, 1577-1586. https://doi.org/10.1002/hep.28785
[3]
Kasper, D., et al. (2012) Harrison’s Principles of Internal Medicine. Vol. 2, 19th Edition, The McGraw-Hill Companies, Inc., New York, 2054-2057.
[4]
De Lusong, M.A., Labio, E., Daez, L. and Gloria, V. (2008) Non-Alcoholic Fatty Liver Disease in the Philippines: Comparable with Other Nations? World Journal of Gastroenterology, 14, 913-917.
[5]
Agrawal, R., Mishra, S., Dixit, V.K. and Rai, S. (2009) Association of Non-Alcoholic Liver Disorder with Obesity. Indian Journal of Preventive and Social Medicine, 40, 127-129.
[6]
Clemente, A.P., Netto, B.D., et al. (2015) Waist Circumference as a Marker for Screening Nonalcoholic Fatty Liver Disease in Obese Adolescents. Revista Paulista de Pediatria: Orgao Oficial da Sociedade de Pediatria de Sao Paulo, 34, 47-55.
[7]
Tsukiyama, H., et al. (2015) Proposed Cut-Off Values of the Waist Circumference for Metabolic Syndrome Based on Visceral Fat Volume in a Japanese Population. Journal of Diabetes Investigation, 7, 587-593. https://doi.org/10.1111/jdi.12454
[8]
Sheth, S.G. and Chopra, S. (2016) Epidemiology, Clinical Features, and Diagnosis of Nonalcoholic Fatty Liver in Adults. https://www.uptodate.com/contents/epidemiology-clinical-features-and-diagnosis-of-nonalcoholic-fatty-liver-disease-in-adults
[9]
Ishibashi, E., et al. (2008) Waist Circumference Correlates with Hepaticfat Accumulation in Male Japanese with Non-Alcoholic Fatty Liver Disease, But Not in females. Journal of Gastroenterology and Hepatology, 23, 908-913.