Background: HIV in pregnant women presented a risk of transmission to newborns. This study was to determine HIV prevalence among pregnant women in the birthing rooms and give antiretrovirals to women infected and their newborns. Methods: A preliminary study was conducted from 2013 to 2015 at the Mother and Child Hospital. Pregnant women were counseled and tested for HIV-antibody according to the national algorithm using Determine HIV 1 & 2 and Immunocomb II Bispot HIV1 & 2. The women screened HIV-negative during the prenatal consultation and who accepted a second test were screened in the birth room. The data collected were processed using the Access Microsoft office 16 and SPSS software version 18. Results: A total of 6080 pregnant women were tested before and in the birth room. Of these, 5943 (97.4%) were detected as HIV-negative and 159 (2.6%) were HIV-positive. Of the 5943 with HIV-negative status, 1333 accepted the second test in the birth room, 10 of which have become HIV-positive. The rate of seroconversions was 0.75%. Conclusion: This study determined the prevalence of HIV in pregnant women. The result reveals the importance and necessity of repeating the screening test in the birth room because of the possibility of seroconversion or new infection during pregnancy.
References
[1]
Ngwej, D.T., Mukuku, O., Mudekereza, R., Karaj, E., Odimba, E.B., Luboya, O.N., Kakoma, J.B. and Wembonyama, S.O. (2015) Study of Risk Factors for HIV Transmission from Mother to Child in the Strategy Option A in Lubumbashi, Democratic Republic of Congo. Pan African Medical Journal, 22, Article No. 8. https://doi.org/10.11604/pamj.2015.22.18.7480
[2]
Aubry, P. (2013) Infection par le VIH/Sida et Tropiques. Actualité 2013, Médecine Tropicale, 17 p.
[3]
Kourtis, A.P., Bulterys, M., Nesheim, S.R. and Lee, F.K. (2001) Understanding the Timing of HIV Transmission from Mother to Infant. JAMA, 285, 709-712. https://doi.org/10.1001/jama.285.6.709
[4]
Boer, K., Nellen, J.F., Kreyenbroek, M.E. and Godfried, M.H. (2009) Treatment of HIV-Infected Pregnant Women: Prevention of Virus Transmission and Adverse Effects in Mother and Child. Nederlands Tijdschrift Voor Geneeskunde, 153, B410.
[5]
Reshi, P. and Lone, I.M. (2010) Human Immunodeficiency Virus and Pregnancy. Archive of Gynecology Obstetrics, 281, 781-792. https://doi.org/10.1007/s00404-009-1334-3
[6]
Ahoua, L., Ayikoru, H., Gnauck, K., Odaru, G., Odar, E., Ondoa-Onama, C., Pinoges, L., Balkan, S., Olson, D. and Pujades-Rodríguez, M. (2010) Evaluation of a 5-Year Program Prevents Mother-to-Child Transmission of HIV Infection in Northern Uganda. Journal of Tropical Pediatrics, 56, 43-52. https://doi.org/10.1093/tropej/fmp054
[7]
Ciaranello, A.L., Perez, F., Keatinge, J., Park, J.-E., Engelsmann, B., Maruva, M., Walensky, R.P., Dabis, F., Chu, J., Rusibamayila, A., Mushavi, A. and Freedberg, K.A. (2012) What Will It Take to Eliminate Pediatric HIV? Reaching WHO Target Rates of Mother-to-Child HIV Transmission in Zimbabwe: A Model-Based Analysis. PLOS Medicine, 9, e1001156. https://doi.org/10.1371/journal.pmed.1001156
[8]
Soubeiga, S.T., Compaore, R., Djigma, F., Zagre, N., Assengone, E., Traore, L., Diarra, B., Bisseye, C., Ouermi, D., Sagna, T., Karou, S., Pietra, V. and Simpore, J. (2015) Evaluation of Antiretroviral Therapy on Mother to Child Transmission HIV in HIV-1 Positive Pregnant Women: Case of St. Camillus Medical Center in Ouagadougou, Burkina Faso. Pan African Medical Journal, 20, Article 399. https://doi.org/10.11604/pamj.2015.20.399.5627
[9]
Faye, A., Le Chenadec, J., Dollfus, C., Thuret, I., Douard, D., Firtion, G. and French Perinatal Study Group (2004) Early versus Deferred Antiretroviral Multidrug Therapy in Infants Infected with HIV Type 1. Clinical Infectious Diseases, 39, 1692-1698. https://doi.org/10.1086/425739
[10]
Goetghebuer, T., Haelterman, E., Le Chenadec, J., Dollfus, C., Gibb, D., Judd, A. and Levy, J. (2009) Effect of Early Antiretroviral Therapy on the Risk of AIDS/Death in HIV-Infected Infants. AIDS, 23, 597-604. https://doi.org/10.1097/QAD.0b013e328326ca37
[11]
WHO (2010) Antiretroviral Drugs for Treating Pregnant Women and Preventing HIV Infections in Infants. Recommendations for a Public Health Approach, 2010 Version. III, Antiretroviral Drugs for Treating Pregnant Women for Their Own Health and to Prevent HIV Infection in Their Infants. WHO, Geneva. https://www.ncbi.nlm.nih.gov/books/NBK304945/
[12]
Enquête Démographique et de Santé et à Indicateurs Multiples au Tchad (EDS-MICS) (2015) Rapport. 655 p. http://dhsprogram.com/pubs/pdf/FR317/FR317
[13]
Dirisu, J.O., Alli, T.O., Adegoke, A.O. and Osazuwa, F. (2011) A Survey of Prevalence of Serum Antibodies to Human Immunodeficiency Deficiency Virus (HIV), Hepatitis B Virus (HBV) and Hepatitis C Virus (HCV) among Blood Donors. North American Journal of Medical Sciences, 3, 35-38. https://doi.org/10.4297/najms.2011.335
[14]
Fouedjio, J.H., Fouelifack, F.Y., Fouelifa, L.D. and Mbu, R.E. (2017) Prevalence and Associated Factors of HIV Infection among Pregnant Women Attending Antenatal Care at the Yaoundé Central Hospital. International Journal of Reproduction Contraception Obstetrics and Gynecology, 6, 2698-2703. https://doi.org/10.18203/2320-1770.ijrcog20172897
[15]
Kabinda, J., Akilimali, T., Miyanga, A., Donnen, P. and Michèle, D. (2015) Hepatitis B, Hepatitis C and HIV in Pregnant Women in the Community in the Democratic Republic of Congo. World Journal of AIDS, 5, 124-130. https://doi.org/10.4236/wja.2015.52015
[16]
Kateng, A.W., Assumani, N.A., Shongo,Ya. P.M., Yansenda, M.P., Mutoke, N.G., Ilunga, M.P. and Luboya, N.O. (2013) Prévalence et facteurs de risque liés á la transmission verticale du VIH. Cas du centre PTME des cliniques universitaires de Lubumbashi. Revue de Médecine du Grands Lacs, 2.
[17]
Okerentugba, P.O., Uchendu, S.C. and Okonko, I.O. (2015) Prevalence of HIV among Pregnant Women in Rumubiakani, Port Harcourt, Nigeria. Public Health Research, 5, 58-65.
[18]
Patil, V.M., Moray, A.P. and Patil, S.P. (2016) Ten Years Trend of HIV Seroprevalence among Indian Pregnant Women Attending Antenatal Clinic at a Tertiary Hospital in Dhule, Maharashtra, India. International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 5, 1514-1519. https://doi.org/10.18203/2320-1770.ijrcog20161315
[19]
Khokar, N., Jethwa, D., Lunagaria, R. and Panchal, N. (2015) Seroprevalence of Hepatitis B, Hepatitis C, Syphilis and HIV in Pregnant Women in a Tertiary Care Hospital, Gujrat, India. International Journal of Current Microbiology and Applied Sciences, 4, 188-194.
[20]
Preetkanwal, S., Mohi, M. and Kumar, A. (2016) Seroprevalence of Human Immunodeficiency Virus among Antenatal Women in One of the Institute of Northern India. Journal of Clinical Diagnostic Research, 10, QC08-QC09. https://doi.org/10.7860/JCDR/2016/20615.8421
[21]
Zeba, M.T., Karou, S.D., Sagna, T., Djigma, F., Bisseye, C., Ouermi, D., Pietra, V., Pignatelli, S., Gnoula, C., Sia, J.D., Moret, R., Nikiema, J.B. and Simpore, J. (2011) HCV Prevalence and Co-Infection with HIV among Pregnant Women in Saint Camille Medical Centre, Ouagadougou. Tropical Medicine and International Health, 16, 1392-1396. https://doi.org/10.1111/j.1365-3156.2011.02845.x
[22]
Billong, S.C., Fokam, J., Billong, E.J., Nguefack-Tsague, G., Essi, M.J., Fodjo, R., Sosso, S.M., Gomba, A., Mosoko-Jembia, J., Loni-Ekali, G., Colizzi, V., Zoung-Kani AC., Bissek, M.F. and Elat Nfetam, J.B. (2015) Distribution épidémiologique de l’infection à VIH chez les femmes enceintes dans les dix régions du Cameroun et implications stratégiques pour les programmes de prévention. Pan African Medical Journal, 20, Article No. 79. https://doi.org/10.11604/pamj.2015.20.79.4216
[23]
Sayare, P.C, Ambhore, N.A., Mantri, R.S. and Karyakarte, R.P. (2017) Prevalence of HIV Infection among Pregnant Women in a Tertiary Care Hospital Akola, India. International Journal of Current Microbiology and Applied Sciences, 6, 691-696. https://doi.org/10.20546/ijcmas.2017.601.083
[24]
Frank-Peterside, N., Okonko, I.O., Okerentugba, P.O. and Jaja, N. (2012) Detection of HIV 1 and 2 Antibodies among Pregnant Women in Port Harcourt, Rivers State, Nigeria. World Applied Sciences Journal, 16, 589-598.
[25]
Ajit, K.N., Manju, K.J., Dhivya, S. and Sumitra, H. (2017) A Study on the Prevalence of HIV Infection among Pregnant Women Attending Antenatal Clinic in a Tertiary Care Hospital, Cuttack, India. International Journal of Community Medicine and Public Health, 4, 1504-1509. https://doi.org/10.18203/2394-6040.ijcmph20171547
[26]
Adebayo, S.B., Olukolade, R.I., Idogho, O., Anyanti, J. and Ankomah, A. (2013) Marital Status and HIV Prevalence in Nigeria: Implications for Effective Prevention Prprogramsor Women. Advances in Infectious Diseases, 3, 3-9. https://doi.org/10.4236/aid.2013.33031
[27]
Maan, M.A., Hussain, F. and Jamil, M. (2014) Prevalence and Risk Factors of HIV in Faisalabad, Pakistan a Retrospective Study. Pakistan Journal of Medical Sciences, 30, 32-35. https://doi.org/10.12669/pjms.301.4176
[28]
Kapulisa, E. (2019) Risk Factors Associated with HIV Seroconversion among Pregnant Women in Southern Province-Zambia. Doctoral Dissertation, The University of Zambia, Lusaka.
[29]
Kinuthia, J., Kiarie, J.N., Farquhar, C., Richardson, B., Nduati, R., Mbori-Ngacha, D. and John-Stewart, G. (2010) Cofactors for HIV-1 Incidence during Pregnancy and the Postpartum Period. Current HIV Research, 8, 510-514. https://doi.org/10.2174/157016210793499213
[30]
Mbena, H., Seni, J., Kajura, A., Matovelo, D. and Kihunrwa, A. (2014) Human Immunodeficiency Virus Seroconversion and Associated Risk Factors among Pregnant Women Delivering at Bugando Medical Center in Mwanza, Tanzania. Annals of Medical and Health Sciences Research, 4, 733-737. https://doi.org/10.4103/2141-9248.141539
[31]
Mbizvo, M.T., Kasule, J., Mahomed, K. and Nathoo, K. (2001) HIV-1 Seroconversion Incidence Following Pregnancy and Delivery among Women Seronegative at Recruitment in Harare, Zimbabwe. Central African Journal of Medicine, 47, 115-118. https://doi.org/10.4314/cajm.v47i5.8600
