Juvenile systemic lupus erythematosus is a rare entity,
affecting children under 16 years of age. Girls are more often affected than
boys and the female predominance increases significantly with age. The initial
manifestations are highly variable with an insidious and progressive onset.
Non-specific symptoms include fever, anorexia, weight loss and asthenia.
Pericarditis is the most common cardiac manifestation in systemic lupus
erythematosus (SLE), occurring in 10% to 40% of cases.The biological elements of the
diagnosis and follow-up of pediatric SLE are identical to those of adults and
are based on regular measurement of complement, native anti-DNA antibodies, and
inflammatory findings. Treatment is essentially based on corticosteroid therapy.
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