小青龙合二陈汤治疗AECOPD外寒内饮证的临床疗效观察
Clinical Observation of Xiaoqinglong Heerchen Decoction in the Treatment of AECOPD with Outer Cold and Inner Drink Syndrome

目的：本研究主要观察小青龙合二陈汤在治疗慢性阻塞性肺疾病急性加重期外寒内饮证的临床疗效和安全性。方法：回顾性分析2020年1月至2022年7月期间就诊于台州市黄岩区中医院的AECOPD外寒内饮证患者75例，并根据住院当天是否开始服用小青龙合二陈汤分为对照组和中药组。观察治疗前后两组患者的白细胞计数、超敏CRP、经皮血氧饱和度、血气分析，并进行生活质量评估、呼吸困难评估、中医临床症状评分表评估，最后对以上各指标和住院时间、住院费用等进行统计学处理和分析。结果：本研究结果显示，中药组的CAT评分、mMRC评分更低，住院费用、住院时间方面有优势，与对照组有显著的统计学差异。结论：小青龙合二陈汤治疗AECOPD外寒内饮证近期疗效较好，能改善其主要症状，缩短住院日期，减少住院费用，从而改善患者急性期的生活质量，提示中医药在缓解和治疗AECOPD外寒内饮证方面有一定优越性，值得推广。
Objective: This study mainly observes the clinical efficacy and safety of Xiaoqinglong Heerchen De-coction in the treatment of acute exacerbation of chronic obstructive pulmonary disease with outer cold and inner drink syndrome. Methods: A retrospective analysis was made of 75 patients with AECOPD who were treated in Huangyan District Traditional Chinese Medicine Hospital of Taizhou City from January 2020 to July 2022 with the syndrome of external cold and internal drinking, and they were divided into control group and traditional Chinese medicine group according to whether they started taking Xiaoqinglong Heerchen Decoction on the day of hospitalization. The white blood cell count, hypersensitivity CRP, transcutaneous oxygen saturation, blood gas analysis of the two groups of patients before and after treatment were observed, and the quality of life, dyspnea, and TCM clinical symptom scores were evaluated. Finally, the above indicators, length of hospital stay, hospitalization cost, etc. were statistically processed and analyzed. Results: The results of this study showed that the traditional Chinese medicine group had lower CAT scores and mMRC scores, and had advantages in terms of hospitalization costs and length of stay, which had significant statistical differences with the control group. Conclusion: Xiaoqinglong Heerchen Decoction has a good short-term curative effect in the treatment of AECOPD with outer cold and inner drink syndrome. It can improve its main symptoms, shorten the length of hospitalization, and reduce hospitalization costs, thereby improving the quality of life of patients in the acute phase, suggesting that traditional Chinese medicine is effective in remission and treatment. AECOPD Outer Cold Inner Drink Syn-drome has certain advantages and is worthy of promotion.