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基于微流控技术的纳米粒子合成自动化装置
Nanoparticle Synthesis Automation Device Based on Microfluidic Technology

DOI: 10.12677/NAT.2022.124028, PP. 283-287

Keywords: 纳米颗粒合成,微流控技术,微流控芯片,纳米粒子合成装置,自动化
Nanoparticle Synthesis
, Microfluidic Technology, Microfluidic Chip, Nanoparticle Synthesis Device, Automation

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Abstract:

纳米颗粒合成技术是实现纳米颗粒应用的关键步骤,传统合成方法在小尺寸大批量合成时,反应条件波动较大,不能精确控制影响反应的相关因素,导致合成结果不理想。采用微流控技术的方法,在微流控芯片中进行纳米粒子合成,可以实现小尺寸大批量合成,为了能很好地控制反应条件,我们设计开发了一种基于微流控技术的纳米粒子合成装置,该装置集成了微流控芯片的流量控制模块、反应温度调节模块、收集模块等,可以实现纳米粒子合成自动化。不但可以得到更加理想的纳米颗粒,而且操作方便,效率大大提高。
Nanoparticle synthesis technology is a key step to realize the application of nanoparticles. The traditional synthesis method is used in small size and mass syn-thesis, the reaction conditions fluctuate greatly, and the related factors affecting the reflection can-not be accurately controlled, resulting in unsatisfactory synthesis results. Using the methods of mi-crofluidic technology, the nanoparticle synthesis in the microfluidic chip can realize the synthesis of large quantities of small size, in order to be a very good control of reaction conditions, we designed and developed a kind of nanoparticle synthesis based on the technology of the microfluidic device, the device integrates the microfluidic chip flow control module, the reaction temperature control module, collection module, etc., nanoparticle synthesis can be automated. It not only can get more ideal nanoparticle particles, but also the operation is more convenient, and the efficiency is greatly improved.

References

[1]  Baker, I. (2018) Magnetic Nanoparticle Synthesis. Nanobiomaterials, 197-229.
https://doi.org/10.1016/B978-0-08-100716-7.00009-X
[2]  Kuhlbusch, T.A.J., Asbach, C., Fissan, H., G?hler, D. and Stintz, M. (2011) Nanoparticle Exposure at Nanotechnology Workplaces: A Review. Particle and Fibre Toxicology, 8, Article No. 22.
https://doi.org/10.1186/1743-8977-8-22
[3]  董广新, 蒋稼欢. 基于微流动混合的微纳米粒子合成进展[J]. 化工进展, 2010, 29(11): 2026-2033+2078.
[4]  Rao, S.V., Vani, D.B.S. and Padmalatha, K. (2021) Development and Characterization of Chitosan Based Flutamide Nanoparticles by Ionic Gelation Method. Research Journal of Pharmacy and Technology, 14, 1668-1672.
https://doi.org/10.5958/0974-360X.2021.00296.1
[5]  Nasir, A., Kausar, A. and Younus, A. (2015) A Review on Preparation, Properties and Applications of Polymeric Nanoparticle-Based Materials. Polymer-Plastics Technology and Engineering, 54, 325-341.
https://doi.org/10.1080/03602559.2014.958780
[6]  Indiarto, R., Indriana, L.P.A., Andoyo, R., Subroto, E. and Nurhadi, B. (2022) Bottom-Up Nanoparticle Synthesis: A Review of Techniques, Polyphenol-Based Core Materials, and Their Properties. European Food Research and Technology, 248, 1-24.
https://doi.org/10.1007/s00217-021-03867-y
[7]  Nie, Y., Jin, C.R. and Zhang, J.X.J. (2021) Microfluidic In Situ Patterning of Silver Nanoparticles for Surface-Enhanced Raman Spectroscopic Sensing of Biomolecules. ACS Sensors, 6, 2584-2592.
https://doi.org/10.1021/acssensors.1c00117
[8]  刘一寰, 胡欣, 朱宁, 等. 基于微流控技术制备微/纳米粒子材料[J]. 化学进展, 2018, 30(8): 1133-1142.
[9]  朱家艺, 贺军辉. 反应条件对乳液法自组装合成氧化锰纳米粒子结构、形貌和尺寸的影响[J]. 化学学报, 2010, 68(10): 961-968.
[10]  张璐. 基于微流控芯片技术的纳米颗粒可控合成[D]: [博士学位论文]. 北京: 中国科学院大学, 2015.

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