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复发性阔韧带骨外尤文氏肉瘤1例报道并文献复习
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Abstract:
目的：探讨复发性骨外尤文氏肉瘤(EES)的疾病特征，了解其临床表现、诊断及治疗方案。方法：对1例阔韧带复发的EES患者的临床资料进行回顾性分析，复习相关文献并进行讨论。结果：该例EES患者临床表现及影像学特征缺乏特异性，确诊依赖于病理，其中免疫组化结果为CD99 (+)，基因检测EWSR1基因易位，复发性EES治疗采用综合治疗，现术后放化疗中，一般状况好。结论：阔韧带EES极其罕见，具有易复发、易转移的特点，宜采取多模式联合的治疗策略，但复发和转移性尤因肉瘤的治疗仍是巨大挑战。
Objective: To investigate the disease characteristics of recurrent extraskeletal Ewing’s sarcoma (EES), and to understand its clinical manifestations, diagnosis and treatment. Methods: The clinical data of one EES patient with parametrial recurrence were retrospectively analyzed, and relevant literatures were reviewed and discussed. Results: The clinical manifestations and imaging features of this EES patient lacked specificity, and the diagnosis depended on pathology. The immunohisto-chemical results were CD99 (+), and the gene detection of EWSR1 gene translocation was performed. The recurrent EES was treated with comprehensive treatment. During chemotherapy, the general condition is good. Conclusion: Parametrial EES is extremely rare, and has the characteristics of easy recurrence and metastasis. A multimodal combined treatment strategy should be adopted, but the treatment of recurrent and metastatic Ewing sarcoma is still a huge challenge.
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