一例头孢噻肟过敏性休克及疑似迟发型超敏反应的案例分析
A Case Analysis of Anaphylactic Shock and Suspected Delayed Type Hypersensitivity of Cefotaxime

抗菌药物过敏一直是临床中关注的重点，无论是在询问患者病史还是在使用药物前的皮试与用药时的核对等都体现出了对抗菌药物使用的重视。抗生素过敏多属于I型超敏反应，可累及多种器官系统产生各种临床症状，具有起病急，症状重且表现复杂的特点，其中过敏性休克是患者死亡的首要因素，有时也可出现少见的迟发性超敏反应，往往会在数天至数周出现，易被忽视、难以诊断及追踪过敏源。目前严重超敏反应并不多见，迟发性超敏反应尤甚，因此很多医务人员少有相关处理治疗经验，本文通过介绍一例济宁市第一人民医院心内科收治的头孢噻肟过敏病人，分析相关疾病及其治疗特点。
Antibacterial drug allergy has always been the focus of clinical attention. Whether it is inquiring about the patient’s medical history or checking the skin test before using the drug and the drug use, it reflects the importance of the use of antibacterial drugs. Antibiotic allergy mostly belongs to type I hypersensitivity reaction, which can involve multiple organ systems and produce various clinical symptoms. It has the characteristics of acute onset, severe symptoms and complex manifestations. Anaphylactic shock is the primary cause of death of patients, and sometimes it can also occur rare delayed hypersensitivity reactions, which often appear over a period of days to weeks, and are easi-ly overlooked and difficult to diagnose and trace. At present, severe hypersensitivity reactions are rare, especially delayed hypersensitivity reactions. Therefore, many medical staff have little expe-rience in related treatment. This article introduces a case of cefotaxime allergic patient admitted to the Department of Cardiology of Jining First People’s Hospital and the related diseases and their treatment characteristics are analyzed.